| Full name: protein Z, vitamin K dependent plasma glycoprotein | Alias Symbol: PZ | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 8858 | HGNC ID: HGNC:9460 | Ensembl Gene: ENSG00000126231 | OMIM ID: 176895 |
| Related drugs: MENADIONE... [more] | |||
Expression of PROZ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PROZ | 8858 | 208034_s_at | -0.0275 | 0.9391 | |
| GSE20347 | PROZ | 8858 | 208034_s_at | 0.1022 | 0.1961 | |
| GSE23400 | PROZ | 8858 | 208034_s_at | 0.0071 | 0.8644 | |
| GSE26886 | PROZ | 8858 | 208034_s_at | -0.0218 | 0.8228 | |
| GSE29001 | PROZ | 8858 | 208034_s_at | -0.0342 | 0.8493 | |
| GSE38129 | PROZ | 8858 | 208034_s_at | 0.0309 | 0.7461 | |
| GSE45670 | PROZ | 8858 | 208034_s_at | 0.1192 | 0.0894 | |
| GSE53622 | PROZ | 8858 | 147531 | 0.7433 | 0.0000 | |
| GSE53624 | PROZ | 8858 | 147531 | 1.4090 | 0.0000 | |
| GSE63941 | PROZ | 8858 | 208034_s_at | 0.0060 | 0.9751 | |
| GSE77861 | PROZ | 8858 | 208034_s_at | -0.0367 | 0.7680 | |
| TCGA | PROZ | 8858 | RNAseq | -1.0759 | 0.0302 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PROZ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PROZ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PROZ | 8858 | 7 | 12 | 11 | |
| GSE20123 | PROZ | 8858 | 7 | 11 | 12 | |
| GSE43470 | PROZ | 8858 | 4 | 15 | 24 | |
| GSE46452 | PROZ | 8858 | 3 | 31 | 25 | |
| GSE47630 | PROZ | 8858 | 3 | 26 | 11 | |
| GSE54993 | PROZ | 8858 | 11 | 4 | 55 | |
| GSE54994 | PROZ | 8858 | 10 | 9 | 34 | |
| GSE60625 | PROZ | 8858 | 0 | 3 | 8 | |
| GSE74703 | PROZ | 8858 | 3 | 11 | 22 | |
| GSE74704 | PROZ | 8858 | 4 | 9 | 7 | |
| TCGA | PROZ | 8858 | 20 | 31 | 45 |
Total number of gains: 72; Total number of losses: 162; Total Number of normals: 254.
Somatic mutations of PROZ:
Generating mutation plots.
Highly correlated genes for PROZ:
Showing top 20/586 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PROZ | ATG10 | 0.705116 | 4 | 0 | 4 |
| PROZ | PRR34 | 0.695122 | 5 | 0 | 4 |
| PROZ | CAMK2B | 0.692072 | 5 | 0 | 5 |
| PROZ | PEAK1 | 0.690908 | 4 | 0 | 4 |
| PROZ | RFPL3 | 0.688859 | 4 | 0 | 4 |
| PROZ | KIR2DS5 | 0.684112 | 5 | 0 | 5 |
| PROZ | ZNF221 | 0.669992 | 3 | 0 | 3 |
| PROZ | AQP2 | 0.668329 | 4 | 0 | 4 |
| PROZ | CGA | 0.668235 | 6 | 0 | 5 |
| PROZ | IFNA17 | 0.667572 | 4 | 0 | 4 |
| PROZ | MEPE | 0.666404 | 5 | 0 | 5 |
| PROZ | RPGRIP1 | 0.662948 | 5 | 0 | 5 |
| PROZ | KHDRBS2 | 0.660593 | 4 | 0 | 4 |
| PROZ | GP2 | 0.655627 | 3 | 0 | 3 |
| PROZ | LRTM1 | 0.655223 | 4 | 0 | 4 |
| PROZ | ESR1 | 0.651724 | 3 | 0 | 3 |
| PROZ | GP1BA | 0.651486 | 5 | 0 | 5 |
| PROZ | C8A | 0.650768 | 4 | 0 | 4 |
| PROZ | PRAMEF12 | 0.649903 | 5 | 0 | 5 |
| PROZ | SNAP91 | 0.647989 | 3 | 0 | 3 |
For details and further investigation, click here
