| Full name: neuronal differentiation 4 | Alias Symbol: Atoh3|ATH-3|MATH-3|bHLHa4 | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 58158 | HGNC ID: HGNC:13802 | Ensembl Gene: ENSG00000123307 | OMIM ID: 611635 |
| Drug and gene relationship at DGIdb | |||
Expression of NEUROD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEUROD4 | 58158 | 221318_at | -0.0626 | 0.8647 | |
| GSE20347 | NEUROD4 | 58158 | 221318_at | 0.0105 | 0.9127 | |
| GSE23400 | NEUROD4 | 58158 | 221318_at | -0.0665 | 0.0811 | |
| GSE26886 | NEUROD4 | 58158 | 221318_at | 0.1176 | 0.4795 | |
| GSE29001 | NEUROD4 | 58158 | 221318_at | -0.2030 | 0.3642 | |
| GSE38129 | NEUROD4 | 58158 | 221318_at | -0.1415 | 0.0973 | |
| GSE45670 | NEUROD4 | 58158 | 221318_at | 0.0227 | 0.8138 | |
| GSE63941 | NEUROD4 | 58158 | 221318_at | 0.0979 | 0.5612 | |
| GSE77861 | NEUROD4 | 58158 | 221318_at | -0.0383 | 0.7566 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEUROD4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NEUROD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEUROD4 | 58158 | 4 | 1 | 25 | |
| GSE20123 | NEUROD4 | 58158 | 4 | 1 | 25 | |
| GSE43470 | NEUROD4 | 58158 | 4 | 0 | 39 | |
| GSE46452 | NEUROD4 | 58158 | 7 | 1 | 51 | |
| GSE47630 | NEUROD4 | 58158 | 10 | 2 | 28 | |
| GSE54993 | NEUROD4 | 58158 | 0 | 5 | 65 | |
| GSE54994 | NEUROD4 | 58158 | 4 | 1 | 48 | |
| GSE60625 | NEUROD4 | 58158 | 0 | 0 | 11 | |
| GSE74703 | NEUROD4 | 58158 | 4 | 0 | 32 | |
| GSE74704 | NEUROD4 | 58158 | 3 | 1 | 16 | |
| TCGA | NEUROD4 | 58158 | 16 | 10 | 70 |
Total number of gains: 56; Total number of losses: 22; Total Number of normals: 410.
Somatic mutations of NEUROD4:
Generating mutation plots.
Highly correlated genes for NEUROD4:
Showing top 20/954 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEUROD4 | CACNA1S | 0.739144 | 5 | 0 | 5 |
| NEUROD4 | GPR4 | 0.714896 | 4 | 0 | 4 |
| NEUROD4 | CDH10 | 0.688811 | 5 | 0 | 5 |
| NEUROD4 | TM4SF5 | 0.687771 | 7 | 0 | 7 |
| NEUROD4 | PRSS53 | 0.686686 | 4 | 0 | 4 |
| NEUROD4 | UBE2D4 | 0.685496 | 4 | 0 | 4 |
| NEUROD4 | LINC00474 | 0.682128 | 4 | 0 | 4 |
| NEUROD4 | CNR2 | 0.679242 | 6 | 0 | 6 |
| NEUROD4 | CDC25C | 0.677726 | 3 | 0 | 3 |
| NEUROD4 | PLG | 0.677171 | 5 | 0 | 4 |
| NEUROD4 | CHRM2 | 0.675978 | 5 | 0 | 5 |
| NEUROD4 | IFNA5 | 0.674681 | 3 | 0 | 3 |
| NEUROD4 | KIR2DS5 | 0.673098 | 6 | 0 | 5 |
| NEUROD4 | RHAG | 0.670797 | 4 | 0 | 3 |
| NEUROD4 | NR1I2 | 0.670757 | 5 | 0 | 5 |
| NEUROD4 | TP53I11 | 0.669766 | 3 | 0 | 3 |
| NEUROD4 | LYPLA2 | 0.668355 | 3 | 0 | 3 |
| NEUROD4 | ADRB1 | 0.668224 | 3 | 0 | 3 |
| NEUROD4 | CAMK2B | 0.667896 | 7 | 0 | 5 |
| NEUROD4 | GLRA1 | 0.664173 | 3 | 0 | 3 |
For details and further investigation, click here
