| Full name: submaxillary gland androgen regulated protein 3A | Alias Symbol: PBI|PRL5 | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 26952 | HGNC ID: HGNC:19216 | Ensembl Gene: ENSG00000109208 | OMIM ID: 618340 |
| Drug and gene relationship at DGIdb | |||
Expression of SMR3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMR3A | 26952 | 214566_at | -0.2131 | 0.3911 | |
| GSE20347 | SMR3A | 26952 | 214566_at | -0.0217 | 0.7488 | |
| GSE23400 | SMR3A | 26952 | 214566_at | -0.1438 | 0.0001 | |
| GSE26886 | SMR3A | 26952 | 214566_at | 0.0428 | 0.6847 | |
| GSE29001 | SMR3A | 26952 | 214566_at | -0.1963 | 0.2103 | |
| GSE38129 | SMR3A | 26952 | 214566_at | -0.0906 | 0.0661 | |
| GSE45670 | SMR3A | 26952 | 214566_at | -0.0517 | 0.5421 | |
| GSE53622 | SMR3A | 26952 | 42315 | -0.2671 | 0.0207 | |
| GSE53624 | SMR3A | 26952 | 42315 | -0.1686 | 0.1884 | |
| GSE63941 | SMR3A | 26952 | 214566_at | 0.0950 | 0.5061 | |
| GSE77861 | SMR3A | 26952 | 214566_at | -0.1138 | 0.2634 | |
| GSE97050 | SMR3A | 26952 | A_23_P41365 | 0.2362 | 0.4152 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMR3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMR3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMR3A | 26952 | 0 | 11 | 19 | |
| GSE20123 | SMR3A | 26952 | 0 | 12 | 18 | |
| GSE43470 | SMR3A | 26952 | 0 | 13 | 30 | |
| GSE46452 | SMR3A | 26952 | 2 | 35 | 22 | |
| GSE47630 | SMR3A | 26952 | 1 | 18 | 21 | |
| GSE54993 | SMR3A | 26952 | 7 | 0 | 63 | |
| GSE54994 | SMR3A | 26952 | 1 | 9 | 43 | |
| GSE60625 | SMR3A | 26952 | 0 | 0 | 11 | |
| GSE74703 | SMR3A | 26952 | 0 | 11 | 25 | |
| GSE74704 | SMR3A | 26952 | 0 | 7 | 13 | |
| TCGA | SMR3A | 26952 | 15 | 28 | 53 |
Total number of gains: 26; Total number of losses: 144; Total Number of normals: 318.
Somatic mutations of SMR3A:
Generating mutation plots.
Highly correlated genes for SMR3A:
Showing top 20/550 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMR3A | MATN1 | 0.702399 | 4 | 0 | 3 |
| SMR3A | DCC | 0.680153 | 4 | 0 | 4 |
| SMR3A | TRIM10 | 0.678856 | 7 | 0 | 6 |
| SMR3A | KRTAP4-7 | 0.674311 | 3 | 0 | 3 |
| SMR3A | GFRA4 | 0.669719 | 5 | 0 | 4 |
| SMR3A | IFNA4 | 0.666917 | 5 | 0 | 5 |
| SMR3A | IFNA14 | 0.663619 | 4 | 0 | 3 |
| SMR3A | ZNF835 | 0.660582 | 6 | 0 | 5 |
| SMR3A | GPR25 | 0.660372 | 4 | 0 | 4 |
| SMR3A | PEX5L | 0.660338 | 3 | 0 | 3 |
| SMR3A | CBLN1 | 0.65967 | 5 | 0 | 5 |
| SMR3A | LMX1B | 0.650451 | 6 | 0 | 5 |
| SMR3A | GPR22 | 0.649916 | 4 | 0 | 3 |
| SMR3A | FERD3L | 0.649138 | 3 | 0 | 3 |
| SMR3A | CACNB3 | 0.648469 | 4 | 0 | 3 |
| SMR3A | ADRA1A | 0.648143 | 3 | 0 | 3 |
| SMR3A | MPL | 0.643839 | 6 | 0 | 5 |
| SMR3A | GJB4 | 0.641933 | 6 | 0 | 6 |
| SMR3A | TNFSF11 | 0.64037 | 6 | 0 | 5 |
| SMR3A | NNAT | 0.639131 | 6 | 0 | 6 |
For details and further investigation, click here
