| Full name: WW domain containing E3 ubiquitin protein ligase 2 | Alias Symbol: AIP2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 11060 | HGNC ID: HGNC:16804 | Ensembl Gene: ENSG00000198373 | OMIM ID: 602308 |
| Drug and gene relationship at DGIdb | |||
Expression of WWP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WWP2 | 11060 | 204022_at | 0.0006 | 0.9994 | |
| GSE20347 | WWP2 | 11060 | 204022_at | -0.3617 | 0.0023 | |
| GSE23400 | WWP2 | 11060 | 210200_at | -0.2020 | 0.0000 | |
| GSE26886 | WWP2 | 11060 | 204022_at | -0.3330 | 0.0610 | |
| GSE29001 | WWP2 | 11060 | 204022_at | -0.2099 | 0.5444 | |
| GSE38129 | WWP2 | 11060 | 204022_at | -0.2129 | 0.1042 | |
| GSE45670 | WWP2 | 11060 | 204022_at | -0.0225 | 0.8789 | |
| GSE53622 | WWP2 | 11060 | 46681 | -0.2448 | 0.0002 | |
| GSE53624 | WWP2 | 11060 | 46681 | -0.2506 | 0.0000 | |
| GSE63941 | WWP2 | 11060 | 204022_at | -0.3495 | 0.3486 | |
| GSE77861 | WWP2 | 11060 | 204022_at | -0.1326 | 0.3967 | |
| GSE97050 | WWP2 | 11060 | A_23_P206684 | -0.0040 | 0.9885 | |
| SRP007169 | WWP2 | 11060 | RNAseq | -0.7330 | 0.0991 | |
| SRP008496 | WWP2 | 11060 | RNAseq | -0.7143 | 0.0220 | |
| SRP064894 | WWP2 | 11060 | RNAseq | -0.7549 | 0.0000 | |
| SRP133303 | WWP2 | 11060 | RNAseq | -0.2923 | 0.0725 | |
| SRP193095 | WWP2 | 11060 | RNAseq | -0.2306 | 0.0645 | |
| SRP219564 | WWP2 | 11060 | RNAseq | -0.2642 | 0.5114 | |
| TCGA | WWP2 | 11060 | RNAseq | -0.1464 | 0.0016 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WWP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WWP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WWP2 | 11060 | 8 | 1 | 21 | |
| GSE20123 | WWP2 | 11060 | 8 | 1 | 21 | |
| GSE43470 | WWP2 | 11060 | 2 | 8 | 33 | |
| GSE46452 | WWP2 | 11060 | 38 | 1 | 20 | |
| GSE47630 | WWP2 | 11060 | 11 | 8 | 21 | |
| GSE54993 | WWP2 | 11060 | 2 | 4 | 64 | |
| GSE54994 | WWP2 | 11060 | 8 | 10 | 35 | |
| GSE60625 | WWP2 | 11060 | 4 | 0 | 7 | |
| GSE74703 | WWP2 | 11060 | 2 | 5 | 29 | |
| GSE74704 | WWP2 | 11060 | 4 | 0 | 16 | |
| TCGA | WWP2 | 11060 | 28 | 13 | 55 |
Total number of gains: 115; Total number of losses: 51; Total Number of normals: 322.
Somatic mutations of WWP2:
Generating mutation plots.
Highly correlated genes for WWP2:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WWP2 | PSG6 | 0.704999 | 3 | 0 | 3 |
| WWP2 | IL9R | 0.699175 | 3 | 0 | 3 |
| WWP2 | DDX4 | 0.683596 | 3 | 0 | 3 |
| WWP2 | OR10H2 | 0.681053 | 3 | 0 | 3 |
| WWP2 | DNMT3L | 0.677649 | 3 | 0 | 3 |
| WWP2 | MED8 | 0.661737 | 5 | 0 | 5 |
| WWP2 | HTR5A | 0.656181 | 3 | 0 | 3 |
| WWP2 | DESI1 | 0.654484 | 3 | 0 | 3 |
| WWP2 | TREML2 | 0.646914 | 4 | 0 | 3 |
| WWP2 | LTB4R2 | 0.642132 | 3 | 0 | 3 |
| WWP2 | ASL | 0.637326 | 6 | 0 | 5 |
| WWP2 | PIGO | 0.63574 | 4 | 0 | 3 |
| WWP2 | GNPTG | 0.633497 | 3 | 0 | 3 |
| WWP2 | CEACAM21 | 0.633325 | 3 | 0 | 3 |
| WWP2 | NR1H4 | 0.632946 | 3 | 0 | 3 |
| WWP2 | ZNF671 | 0.631287 | 3 | 0 | 3 |
| WWP2 | S100A5 | 0.627724 | 3 | 0 | 3 |
| WWP2 | SCYL2 | 0.624941 | 5 | 0 | 4 |
| WWP2 | GPR50 | 0.616698 | 3 | 0 | 3 |
| WWP2 | GEMIN7 | 0.609797 | 4 | 0 | 3 |
For details and further investigation, click here
