| Full name: xin actin binding repeat containing 1 | Alias Symbol: DKFZp451D042|Xin | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 165904 | HGNC ID: HGNC:14301 | Ensembl Gene: ENSG00000168334 | OMIM ID: 609777 |
| Drug and gene relationship at DGIdb | |||
Expression of XIRP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XIRP1 | 165904 | 235042_at | -0.0926 | 0.7181 | |
| GSE26886 | XIRP1 | 165904 | 235042_at | -0.2140 | 0.0738 | |
| GSE45670 | XIRP1 | 165904 | 235042_at | 0.0761 | 0.4742 | |
| GSE53622 | XIRP1 | 165904 | 72077 | 0.7105 | 0.0003 | |
| GSE53624 | XIRP1 | 165904 | 72077 | 1.0404 | 0.0000 | |
| GSE63941 | XIRP1 | 165904 | 235042_at | -0.0152 | 0.9412 | |
| GSE77861 | XIRP1 | 165904 | 235042_at | -0.0355 | 0.7796 | |
| GSE97050 | XIRP1 | 165904 | A_32_P345659 | -0.6437 | 0.4934 | |
| SRP133303 | XIRP1 | 165904 | RNAseq | 3.5119 | 0.0000 | |
| TCGA | XIRP1 | 165904 | RNAseq | -0.4493 | 0.2459 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by XIRP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XIRP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XIRP1 | 165904 | 0 | 19 | 11 | |
| GSE20123 | XIRP1 | 165904 | 0 | 19 | 11 | |
| GSE43470 | XIRP1 | 165904 | 0 | 20 | 23 | |
| GSE46452 | XIRP1 | 165904 | 2 | 17 | 40 | |
| GSE47630 | XIRP1 | 165904 | 1 | 25 | 14 | |
| GSE54993 | XIRP1 | 165904 | 7 | 2 | 61 | |
| GSE54994 | XIRP1 | 165904 | 1 | 33 | 19 | |
| GSE60625 | XIRP1 | 165904 | 5 | 0 | 6 | |
| GSE74703 | XIRP1 | 165904 | 0 | 16 | 20 | |
| GSE74704 | XIRP1 | 165904 | 0 | 13 | 7 | |
| TCGA | XIRP1 | 165904 | 2 | 70 | 24 |
Total number of gains: 18; Total number of losses: 234; Total Number of normals: 236.
Somatic mutations of XIRP1:
Generating mutation plots.
Highly correlated genes for XIRP1:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XIRP1 | SPEF2 | 0.708256 | 3 | 0 | 3 |
| XIRP1 | ZGLP1 | 0.701704 | 3 | 0 | 3 |
| XIRP1 | AMHR2 | 0.676549 | 3 | 0 | 3 |
| XIRP1 | RAPGEF4-AS1 | 0.673753 | 3 | 0 | 3 |
| XIRP1 | PRAMEF12 | 0.665801 | 4 | 0 | 3 |
| XIRP1 | NEURL2 | 0.665537 | 3 | 0 | 3 |
| XIRP1 | LINC00382 | 0.656554 | 3 | 0 | 3 |
| XIRP1 | CACNA1G | 0.645187 | 3 | 0 | 3 |
| XIRP1 | SLC22A8 | 0.642013 | 3 | 0 | 3 |
| XIRP1 | CD300LB | 0.618659 | 3 | 0 | 3 |
| XIRP1 | DPP6 | 0.618232 | 3 | 0 | 3 |
| XIRP1 | CD1B | 0.615453 | 3 | 0 | 3 |
| XIRP1 | OPTC | 0.606468 | 4 | 0 | 3 |
| XIRP1 | CD300LG | 0.605798 | 4 | 0 | 3 |
| XIRP1 | CCDC157 | 0.60291 | 3 | 0 | 3 |
| XIRP1 | TMEM108 | 0.599336 | 3 | 0 | 3 |
| XIRP1 | C22orf39 | 0.598527 | 4 | 0 | 3 |
| XIRP1 | SRCIN1 | 0.593649 | 3 | 0 | 3 |
| XIRP1 | MYOZ3 | 0.590798 | 4 | 0 | 3 |
| XIRP1 | ZNF568 | 0.590555 | 3 | 0 | 3 |
For details and further investigation, click here
