| Full name: chromosome 22 open reading frame 39 | Alias Symbol: MGC74441 | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 128977 | HGNC ID: HGNC:27012 | Ensembl Gene: ENSG00000242259 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C22orf39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C22orf39 | 128977 | 1553974_at | -0.5475 | 0.3190 | |
| GSE26886 | C22orf39 | 128977 | 227086_at | -0.1081 | 0.4876 | |
| GSE45670 | C22orf39 | 128977 | 1553974_at | -0.4597 | 0.0405 | |
| GSE53622 | C22orf39 | 128977 | 111413 | -0.3960 | 0.0053 | |
| GSE53624 | C22orf39 | 128977 | 111413 | 0.0358 | 0.7544 | |
| GSE63941 | C22orf39 | 128977 | 1553974_at | 0.0432 | 0.9510 | |
| GSE77861 | C22orf39 | 128977 | 227086_at | 0.1479 | 0.1368 | |
| GSE97050 | C22orf39 | A_21_P0000062 | -0.0587 | 0.7921 | ||
| SRP007169 | C22orf39 | 128977 | RNAseq | 0.7663 | 0.1398 | |
| SRP008496 | C22orf39 | 128977 | RNAseq | 0.6885 | 0.0480 | |
| SRP064894 | C22orf39 | 128977 | RNAseq | 0.2440 | 0.2384 | |
| SRP133303 | C22orf39 | 128977 | RNAseq | -0.2434 | 0.1917 | |
| SRP159526 | C22orf39 | 128977 | RNAseq | 0.2120 | 0.2766 | |
| SRP193095 | C22orf39 | 128977 | RNAseq | -0.1800 | 0.0600 | |
| SRP219564 | C22orf39 | 128977 | RNAseq | -0.3620 | 0.4190 | |
| TCGA | C22orf39 | 128977 | RNAseq | -0.2855 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C22orf39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C22orf39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C22orf39 | 128977 | 4 | 7 | 19 | |
| GSE20123 | C22orf39 | 128977 | 4 | 7 | 19 | |
| GSE43470 | C22orf39 | 128977 | 4 | 6 | 33 | |
| GSE46452 | C22orf39 | 128977 | 33 | 1 | 25 | |
| GSE47630 | C22orf39 | 128977 | 8 | 5 | 27 | |
| GSE54993 | C22orf39 | 128977 | 3 | 7 | 60 | |
| GSE54994 | C22orf39 | 128977 | 12 | 7 | 34 | |
| GSE60625 | C22orf39 | 128977 | 5 | 0 | 6 | |
| GSE74703 | C22orf39 | 128977 | 4 | 4 | 28 | |
| GSE74704 | C22orf39 | 128977 | 2 | 4 | 14 | |
| TCGA | C22orf39 | 128977 | 27 | 17 | 52 |
Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.
Somatic mutations of C22orf39:
Generating mutation plots.
Highly correlated genes for C22orf39:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C22orf39 | NXPH3 | 0.764985 | 3 | 0 | 3 |
| C22orf39 | PGPEP1 | 0.758514 | 3 | 0 | 3 |
| C22orf39 | C22orf23 | 0.749123 | 3 | 0 | 3 |
| C22orf39 | MYL4 | 0.719969 | 3 | 0 | 3 |
| C22orf39 | PLB1 | 0.716283 | 3 | 0 | 3 |
| C22orf39 | ADRA1B | 0.712556 | 3 | 0 | 3 |
| C22orf39 | MUC8 | 0.694359 | 3 | 0 | 3 |
| C22orf39 | ADAP1 | 0.688712 | 3 | 0 | 3 |
| C22orf39 | SP7 | 0.678404 | 3 | 0 | 3 |
| C22orf39 | CTIF | 0.667396 | 3 | 0 | 3 |
| C22orf39 | ROS1 | 0.667379 | 3 | 0 | 3 |
| C22orf39 | CALCOCO1 | 0.667147 | 4 | 0 | 3 |
| C22orf39 | LY6H | 0.658648 | 4 | 0 | 3 |
| C22orf39 | SLC2A11 | 0.656203 | 4 | 0 | 3 |
| C22orf39 | GRIN2A | 0.651611 | 3 | 0 | 3 |
| C22orf39 | ATP6AP1L | 0.650883 | 4 | 0 | 3 |
| C22orf39 | FIGLA | 0.649775 | 3 | 0 | 3 |
| C22orf39 | VIPR2 | 0.645924 | 4 | 0 | 3 |
| C22orf39 | RAX | 0.639315 | 3 | 0 | 3 |
| C22orf39 | IL17D | 0.635646 | 4 | 0 | 3 |
For details and further investigation, click here
