| Full name: translin | Alias Symbol: TRSLN|BCLF-1|REHF-1 | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 7247 | HGNC ID: HGNC:12379 | Ensembl Gene: ENSG00000211460 | OMIM ID: 600575 |
| Drug and gene relationship at DGIdb | |||
Expression of TSN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSN | 7247 | 201515_s_at | 0.7923 | 0.0985 | |
| GSE20347 | TSN | 7247 | 201515_s_at | 0.4746 | 0.0020 | |
| GSE23400 | TSN | 7247 | 201515_s_at | 0.7751 | 0.0000 | |
| GSE26886 | TSN | 7247 | 201515_s_at | -0.0371 | 0.8677 | |
| GSE29001 | TSN | 7247 | 201515_s_at | 0.6555 | 0.0375 | |
| GSE38129 | TSN | 7247 | 201515_s_at | 0.6742 | 0.0000 | |
| GSE45670 | TSN | 7247 | 201515_s_at | 0.4169 | 0.0041 | |
| GSE53622 | TSN | 7247 | 128890 | 0.5667 | 0.0000 | |
| GSE53624 | TSN | 7247 | 128890 | 0.7259 | 0.0000 | |
| GSE63941 | TSN | 7247 | 201515_s_at | 0.0224 | 0.9570 | |
| GSE77861 | TSN | 7247 | 201515_s_at | 0.6544 | 0.0505 | |
| GSE97050 | TSN | 7247 | A_24_P242820 | 0.4712 | 0.2112 | |
| SRP007169 | TSN | 7247 | RNAseq | 0.8916 | 0.0360 | |
| SRP008496 | TSN | 7247 | RNAseq | 0.9329 | 0.0003 | |
| SRP064894 | TSN | 7247 | RNAseq | 0.4809 | 0.0001 | |
| SRP133303 | TSN | 7247 | RNAseq | 0.4935 | 0.0024 | |
| SRP159526 | TSN | 7247 | RNAseq | 0.3146 | 0.0410 | |
| SRP193095 | TSN | 7247 | RNAseq | 0.1672 | 0.1804 | |
| SRP219564 | TSN | 7247 | RNAseq | 0.0690 | 0.8188 | |
| TCGA | TSN | 7247 | RNAseq | 0.2195 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSN | 7247 | 6 | 3 | 21 | |
| GSE20123 | TSN | 7247 | 6 | 3 | 21 | |
| GSE43470 | TSN | 7247 | 3 | 1 | 39 | |
| GSE46452 | TSN | 7247 | 1 | 3 | 55 | |
| GSE47630 | TSN | 7247 | 6 | 0 | 34 | |
| GSE54993 | TSN | 7247 | 0 | 6 | 64 | |
| GSE54994 | TSN | 7247 | 12 | 0 | 41 | |
| GSE60625 | TSN | 7247 | 0 | 3 | 8 | |
| GSE74703 | TSN | 7247 | 3 | 1 | 32 | |
| GSE74704 | TSN | 7247 | 3 | 2 | 15 | |
| TCGA | TSN | 7247 | 31 | 5 | 60 |
Total number of gains: 71; Total number of losses: 27; Total Number of normals: 390.
Somatic mutations of TSN:
Generating mutation plots.
Highly correlated genes for TSN:
Showing top 20/1923 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSN | EME1 | 0.765092 | 3 | 0 | 3 |
| TSN | ISY1 | 0.76172 | 4 | 0 | 4 |
| TSN | LRRC58 | 0.755031 | 4 | 0 | 4 |
| TSN | WDR89 | 0.752877 | 4 | 0 | 4 |
| TSN | FAM161A | 0.75083 | 4 | 0 | 4 |
| TSN | UCK2 | 0.745238 | 3 | 0 | 3 |
| TSN | STARD7 | 0.745062 | 12 | 0 | 12 |
| TSN | REST | 0.741881 | 3 | 0 | 3 |
| TSN | CENPL | 0.741729 | 6 | 0 | 6 |
| TSN | MCM6 | 0.740835 | 10 | 0 | 10 |
| TSN | MMS22L | 0.740701 | 3 | 0 | 3 |
| TSN | C1orf112 | 0.736604 | 8 | 0 | 8 |
| TSN | RANBP1 | 0.736443 | 9 | 0 | 9 |
| TSN | USP42 | 0.735979 | 4 | 0 | 4 |
| TSN | SMYD5 | 0.734513 | 4 | 0 | 4 |
| TSN | GNG10 | 0.733994 | 3 | 0 | 3 |
| TSN | RCN2 | 0.733919 | 7 | 0 | 7 |
| TSN | MED30 | 0.727545 | 6 | 0 | 6 |
| TSN | MRPS23 | 0.727501 | 6 | 0 | 6 |
| TSN | PPT1 | 0.726349 | 11 | 0 | 10 |
For details and further investigation, click here
