| Full name: xylulokinase | Alias Symbol: FLJ10343|FLJ12539 | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 9942 | HGNC ID: HGNC:12839 | Ensembl Gene: ENSG00000093217 | OMIM ID: 604049 |
| Drug and gene relationship at DGIdb | |||
Expression of XYLB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XYLB | 9942 | 208318_s_at | 0.3793 | 0.2419 | |
| GSE20347 | XYLB | 9942 | 208318_s_at | 0.0159 | 0.8488 | |
| GSE23400 | XYLB | 9942 | 208318_s_at | -0.0292 | 0.4014 | |
| GSE26886 | XYLB | 9942 | 208318_s_at | -0.0254 | 0.8177 | |
| GSE29001 | XYLB | 9942 | 208318_s_at | 0.0267 | 0.8646 | |
| GSE38129 | XYLB | 9942 | 208318_s_at | 0.0391 | 0.5972 | |
| GSE45670 | XYLB | 9942 | 208318_s_at | 0.1087 | 0.3574 | |
| GSE53622 | XYLB | 9942 | 58054 | -0.2677 | 0.0396 | |
| GSE53624 | XYLB | 9942 | 58054 | -0.1650 | 0.1249 | |
| GSE63941 | XYLB | 9942 | 1569683_at | 0.1290 | 0.3937 | |
| GSE77861 | XYLB | 9942 | 1569683_at | -0.1320 | 0.3374 | |
| GSE97050 | XYLB | 9942 | A_23_P212423 | -0.0357 | 0.8922 | |
| SRP007169 | XYLB | 9942 | RNAseq | 0.5394 | 0.3434 | |
| SRP064894 | XYLB | 9942 | RNAseq | 0.0974 | 0.5963 | |
| SRP133303 | XYLB | 9942 | RNAseq | -0.1307 | 0.3753 | |
| SRP159526 | XYLB | 9942 | RNAseq | 0.4220 | 0.3325 | |
| SRP193095 | XYLB | 9942 | RNAseq | -0.1344 | 0.2641 | |
| SRP219564 | XYLB | 9942 | RNAseq | 0.2963 | 0.5575 | |
| TCGA | XYLB | 9942 | RNAseq | -0.1679 | 0.1629 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by XYLB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XYLB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XYLB | 9942 | 0 | 19 | 11 | |
| GSE20123 | XYLB | 9942 | 0 | 19 | 11 | |
| GSE43470 | XYLB | 9942 | 0 | 20 | 23 | |
| GSE46452 | XYLB | 9942 | 2 | 17 | 40 | |
| GSE47630 | XYLB | 9942 | 1 | 25 | 14 | |
| GSE54993 | XYLB | 9942 | 6 | 3 | 61 | |
| GSE54994 | XYLB | 9942 | 0 | 34 | 19 | |
| GSE60625 | XYLB | 9942 | 5 | 0 | 6 | |
| GSE74703 | XYLB | 9942 | 0 | 16 | 20 | |
| GSE74704 | XYLB | 9942 | 0 | 13 | 7 | |
| TCGA | XYLB | 9942 | 1 | 71 | 24 |
Total number of gains: 15; Total number of losses: 237; Total Number of normals: 236.
Somatic mutations of XYLB:
Generating mutation plots.
Highly correlated genes for XYLB:
Showing top 20/131 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XYLB | SLFNL1 | 0.748425 | 3 | 0 | 3 |
| XYLB | SCML4 | 0.727194 | 3 | 0 | 3 |
| XYLB | CCDC85C | 0.708041 | 4 | 0 | 3 |
| XYLB | TRIM47 | 0.703345 | 3 | 0 | 3 |
| XYLB | SPIC | 0.701714 | 3 | 0 | 3 |
| XYLB | TRMT2B | 0.681392 | 3 | 0 | 3 |
| XYLB | HS6ST1 | 0.679905 | 5 | 0 | 5 |
| XYLB | TMEM86B | 0.679104 | 3 | 0 | 3 |
| XYLB | EIF4A2 | 0.67409 | 3 | 0 | 3 |
| XYLB | SERPIND1 | 0.671844 | 3 | 0 | 3 |
| XYLB | FAM76A | 0.671588 | 4 | 0 | 4 |
| XYLB | SIDT1 | 0.66607 | 3 | 0 | 3 |
| XYLB | GNL3L | 0.663542 | 3 | 0 | 3 |
| XYLB | KCNC4 | 0.654832 | 5 | 0 | 4 |
| XYLB | NEK6 | 0.654084 | 3 | 0 | 3 |
| XYLB | STAT2 | 0.642698 | 4 | 0 | 4 |
| XYLB | AVPR1A | 0.637321 | 3 | 0 | 3 |
| XYLB | PPP4R4 | 0.633903 | 3 | 0 | 3 |
| XYLB | KLRC4 | 0.6332 | 4 | 0 | 3 |
| XYLB | IQCG | 0.633068 | 3 | 0 | 3 |
For details and further investigation, click here
