YWHAQ

 

Full name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta Alias Symbol: HS1|14-3-3
Type: protein-coding gene Cytoband: 2p25.1
Entrez ID: 10971 HGNC ID: HGNC:12854 Ensembl Gene: ENSG00000134308 OMIM ID: 609009
Drug and gene relationship at DGIdb

 

YWHAQ involved pathways:

KEGG pathway Description View
hsa04110Cell cycle
hsa04114Oocyte meiosis
hsa04151PI3K-Akt signaling pathway
hsa04390Hippo signaling pathway

 

Expression of YWHAQ:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 YWHAQ 10971 213699_s_at 0.1581 0.6135
GSE20347 YWHAQ 10971 213699_s_at 0.2472 0.0341
GSE23400 YWHAQ 10971 213699_s_at 0.4263 0.0000
GSE26886 YWHAQ 10971 212426_s_at -0.1085 0.4249
GSE29001 YWHAQ 10971 213699_s_at 0.2629 0.0835
GSE38129 YWHAQ 10971 213699_s_at 0.3358 0.0001
GSE45670 YWHAQ 10971 213699_s_at 0.3275 0.0038
GSE53622 YWHAQ 10971 34278 0.5820 0.0000
GSE53624 YWHAQ 10971 34278 0.4804 0.0000
GSE63941 YWHAQ 10971 213699_s_at -0.4284 0.0655
GSE77861 YWHAQ 10971 213699_s_at 0.2838 0.0859
GSE97050 YWHAQ 10971 A_23_P131723 0.5069 0.1344
SRP007169 YWHAQ 10971 RNAseq -0.5774 0.1012
SRP008496 YWHAQ 10971 RNAseq -0.3756 0.1842
SRP064894 YWHAQ 10971 RNAseq 0.1176 0.4685
SRP133303 YWHAQ 10971 RNAseq 0.6560 0.0003
SRP159526 YWHAQ 10971 RNAseq 0.5254 0.0288
SRP193095 YWHAQ 10971 RNAseq 0.3251 0.0649
SRP219564 YWHAQ 10971 RNAseq 0.1540 0.6480
TCGA YWHAQ 10971 RNAseq 0.1356 0.0005

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by YWHAQ expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of YWHAQ:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 YWHAQ 10971 11 2 17
GSE20123 YWHAQ 10971 11 2 17
GSE43470 YWHAQ 10971 2 1 40
GSE46452 YWHAQ 10971 3 4 52
GSE47630 YWHAQ 10971 7 0 33
GSE54993 YWHAQ 10971 0 7 63
GSE54994 YWHAQ 10971 11 0 42
GSE60625 YWHAQ 10971 0 3 8
GSE74703 YWHAQ 10971 2 0 34
GSE74704 YWHAQ 10971 9 1 10
TCGA YWHAQ 10971 34 5 57

Total number of gains: 90; Total number of losses: 25; Total Number of normals: 373.  

 

Somatic mutations of YWHAQ:

 

Generating mutation plots.

 

Highly correlated genes for YWHAQ:

 

Showing top 20/573 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
YWHAQALPK20.693328303
YWHAQTUBA4A0.673311303
YWHAQLINC006210.666576303
YWHAQGLIS20.666433303
YWHAQADAM170.6626691009
YWHAQSPRY4-IT10.661853303
YWHAQSH2D50.65302505
YWHAQSPRR2G0.64997403
YWHAQC16orf740.647041404
YWHAQKRTDAP0.646627403
YWHAQSH3RF30.641898303
YWHAQMSANTD30.629716605
YWHAQFBLIM10.628981504
YWHAQSH3KBP10.627241303
YWHAQPRIM20.625735705
YWHAQADAMTS120.623771605
YWHAQSNRPG0.6208031009
YWHAQTUBG10.620445908
YWHAQCKAP2L0.620148604
YWHAQPSMA40.6195491009

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