| Full name: cytoskeleton associated protein 2 like | Alias Symbol: FLJ40629|radmis | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 150468 | HGNC ID: HGNC:26877 | Ensembl Gene: ENSG00000169607 | OMIM ID: 616174 |
| Drug and gene relationship at DGIdb | |||
Expression of CKAP2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CKAP2L | 150468 | 229610_at | 1.3676 | 0.0325 | |
| GSE26886 | CKAP2L | 150468 | 229610_at | 0.3059 | 0.1989 | |
| GSE45670 | CKAP2L | 150468 | 229610_at | 1.0755 | 0.0005 | |
| GSE53622 | CKAP2L | 150468 | 21047 | 1.1735 | 0.0000 | |
| GSE53624 | CKAP2L | 150468 | 21047 | 1.5643 | 0.0000 | |
| GSE63941 | CKAP2L | 150468 | 229610_at | 2.7846 | 0.0000 | |
| GSE77861 | CKAP2L | 150468 | 229610_at | 0.5608 | 0.0070 | |
| GSE97050 | CKAP2L | 150468 | A_23_P388812 | 0.5643 | 0.1782 | |
| SRP007169 | CKAP2L | 150468 | RNAseq | 1.8636 | 0.0001 | |
| SRP008496 | CKAP2L | 150468 | RNAseq | 1.8837 | 0.0000 | |
| SRP064894 | CKAP2L | 150468 | RNAseq | 1.4877 | 0.0000 | |
| SRP133303 | CKAP2L | 150468 | RNAseq | 1.6727 | 0.0000 | |
| SRP159526 | CKAP2L | 150468 | RNAseq | 1.2443 | 0.0005 | |
| SRP193095 | CKAP2L | 150468 | RNAseq | 1.0150 | 0.0000 | |
| SRP219564 | CKAP2L | 150468 | RNAseq | 0.8376 | 0.2346 | |
| TCGA | CKAP2L | 150468 | RNAseq | 1.4030 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by CKAP2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CKAP2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CKAP2L | 150468 | 6 | 2 | 22 | |
| GSE20123 | CKAP2L | 150468 | 6 | 2 | 22 | |
| GSE43470 | CKAP2L | 150468 | 3 | 1 | 39 | |
| GSE46452 | CKAP2L | 150468 | 1 | 4 | 54 | |
| GSE47630 | CKAP2L | 150468 | 7 | 0 | 33 | |
| GSE54993 | CKAP2L | 150468 | 0 | 6 | 64 | |
| GSE54994 | CKAP2L | 150468 | 10 | 0 | 43 | |
| GSE60625 | CKAP2L | 150468 | 0 | 3 | 8 | |
| GSE74703 | CKAP2L | 150468 | 3 | 1 | 32 | |
| GSE74704 | CKAP2L | 150468 | 3 | 2 | 15 | |
| TCGA | CKAP2L | 150468 | 31 | 6 | 59 |
Total number of gains: 70; Total number of losses: 27; Total Number of normals: 391.
Somatic mutations of CKAP2L:
Generating mutation plots.
Highly correlated genes for CKAP2L:
Showing top 20/1738 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CKAP2L | GINS4 | 0.849068 | 4 | 0 | 4 |
| CKAP2L | NCAPH | 0.816917 | 5 | 0 | 5 |
| CKAP2L | CDK1 | 0.797268 | 8 | 0 | 8 |
| CKAP2L | BUB1 | 0.796144 | 9 | 0 | 9 |
| CKAP2L | SPAG5 | 0.783595 | 8 | 0 | 8 |
| CKAP2L | TIMELESS | 0.78023 | 7 | 0 | 7 |
| CKAP2L | CDC45 | 0.778318 | 8 | 0 | 8 |
| CKAP2L | RFC2 | 0.776398 | 7 | 0 | 7 |
| CKAP2L | NCAPG2 | 0.776165 | 7 | 0 | 7 |
| CKAP2L | HMMR | 0.775385 | 9 | 0 | 9 |
| CKAP2L | KIF4A | 0.774406 | 7 | 0 | 7 |
| CKAP2L | BUB1B | 0.773694 | 5 | 0 | 5 |
| CKAP2L | ATAD2 | 0.773134 | 8 | 0 | 8 |
| CKAP2L | POLR2D | 0.772706 | 7 | 0 | 7 |
| CKAP2L | CEP55 | 0.771344 | 9 | 0 | 9 |
| CKAP2L | KIF23 | 0.771266 | 8 | 0 | 8 |
| CKAP2L | PCNA | 0.770898 | 7 | 0 | 7 |
| CKAP2L | PLK1 | 0.770518 | 7 | 0 | 7 |
| CKAP2L | TTK | 0.767227 | 9 | 0 | 9 |
| CKAP2L | RAD51 | 0.763302 | 7 | 0 | 7 |
For details and further investigation, click here
