| Full name: proteasome subunit alpha 4 | Alias Symbol: HC9|HsT17706 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 5685 | HGNC ID: HGNC:9533 | Ensembl Gene: ENSG00000041357 | OMIM ID: 176846 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMA4 | 5685 | 203396_at | 0.3580 | 0.2089 | |
| GSE20347 | PSMA4 | 5685 | 203396_at | 0.4469 | 0.0043 | |
| GSE23400 | PSMA4 | 5685 | 203396_at | 0.6778 | 0.0000 | |
| GSE26886 | PSMA4 | 5685 | 203396_at | 0.0344 | 0.8462 | |
| GSE29001 | PSMA4 | 5685 | 203396_at | 0.3638 | 0.0930 | |
| GSE38129 | PSMA4 | 5685 | 203396_at | 0.6258 | 0.0000 | |
| GSE45670 | PSMA4 | 5685 | 203396_at | 0.5689 | 0.0000 | |
| GSE53622 | PSMA4 | 5685 | 145317 | 0.7047 | 0.0000 | |
| GSE53624 | PSMA4 | 5685 | 145317 | 0.7593 | 0.0000 | |
| GSE63941 | PSMA4 | 5685 | 203396_at | 0.6124 | 0.0128 | |
| GSE77861 | PSMA4 | 5685 | 203396_at | 0.4277 | 0.1417 | |
| GSE97050 | PSMA4 | 5685 | A_24_P124992 | 0.1985 | 0.3828 | |
| SRP007169 | PSMA4 | 5685 | RNAseq | 0.6702 | 0.0913 | |
| SRP008496 | PSMA4 | 5685 | RNAseq | 0.7985 | 0.0011 | |
| SRP064894 | PSMA4 | 5685 | RNAseq | 0.5490 | 0.0015 | |
| SRP133303 | PSMA4 | 5685 | RNAseq | 0.7959 | 0.0004 | |
| SRP159526 | PSMA4 | 5685 | RNAseq | 0.4833 | 0.0336 | |
| SRP193095 | PSMA4 | 5685 | RNAseq | 0.1644 | 0.3004 | |
| SRP219564 | PSMA4 | 5685 | RNAseq | 0.4199 | 0.1797 | |
| TCGA | PSMA4 | 5685 | RNAseq | 0.2457 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMA4 | 5685 | 7 | 1 | 22 | |
| GSE20123 | PSMA4 | 5685 | 7 | 1 | 22 | |
| GSE43470 | PSMA4 | 5685 | 4 | 5 | 34 | |
| GSE46452 | PSMA4 | 5685 | 3 | 7 | 49 | |
| GSE47630 | PSMA4 | 5685 | 8 | 10 | 22 | |
| GSE54993 | PSMA4 | 5685 | 5 | 6 | 59 | |
| GSE54994 | PSMA4 | 5685 | 5 | 6 | 42 | |
| GSE60625 | PSMA4 | 5685 | 4 | 0 | 7 | |
| GSE74703 | PSMA4 | 5685 | 4 | 3 | 29 | |
| GSE74704 | PSMA4 | 5685 | 3 | 1 | 16 | |
| TCGA | PSMA4 | 5685 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of PSMA4:
Generating mutation plots.
Highly correlated genes for PSMA4:
Showing top 20/1633 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMA4 | OSBPL6 | 0.764054 | 3 | 0 | 3 |
| PSMA4 | C6orf141 | 0.76342 | 3 | 0 | 3 |
| PSMA4 | KREMEN1 | 0.750748 | 3 | 0 | 3 |
| PSMA4 | KIF23 | 0.748417 | 12 | 0 | 12 |
| PSMA4 | ROMO1 | 0.742181 | 3 | 0 | 3 |
| PSMA4 | BOLA3 | 0.740573 | 6 | 0 | 6 |
| PSMA4 | RNGTT | 0.736713 | 3 | 0 | 3 |
| PSMA4 | PRC1 | 0.735899 | 12 | 0 | 12 |
| PSMA4 | PSMD14 | 0.735568 | 11 | 0 | 10 |
| PSMA4 | KNSTRN | 0.735255 | 6 | 0 | 6 |
| PSMA4 | MMS22L | 0.735232 | 3 | 0 | 3 |
| PSMA4 | CCT6A | 0.730662 | 9 | 0 | 9 |
| PSMA4 | FAM89A | 0.730114 | 3 | 0 | 3 |
| PSMA4 | LRRC28 | 0.718382 | 3 | 0 | 3 |
| PSMA4 | CDK1 | 0.718225 | 10 | 0 | 10 |
| PSMA4 | TIPIN | 0.711916 | 12 | 0 | 11 |
| PSMA4 | SUMO2 | 0.711022 | 3 | 0 | 3 |
| PSMA4 | ANKS6 | 0.710462 | 3 | 0 | 3 |
| PSMA4 | SNRPG | 0.708435 | 12 | 0 | 10 |
| PSMA4 | LSM5 | 0.705841 | 12 | 0 | 10 |
For details and further investigation, click here
