| Full name: POM121 and ZP3 fusion | Alias Symbol: POM-ZP3|POM121 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 22932 | HGNC ID: HGNC:9203 | Ensembl Gene: ENSG00000146707 | OMIM ID: 600587 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of POMZP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POMZP3 | 22932 | 210910_s_at | 0.3297 | 0.6635 | |
| GSE20347 | POMZP3 | 22932 | 210910_s_at | 0.9108 | 0.0001 | |
| GSE23400 | POMZP3 | 22932 | 210910_s_at | 0.3713 | 0.0000 | |
| GSE26886 | POMZP3 | 22932 | 210910_s_at | 1.3556 | 0.0022 | |
| GSE29001 | POMZP3 | 22932 | 210910_s_at | 0.4459 | 0.0980 | |
| GSE38129 | POMZP3 | 22932 | 210910_s_at | 0.7553 | 0.0001 | |
| GSE45670 | POMZP3 | 22932 | 210910_s_at | 0.9447 | 0.0004 | |
| GSE63941 | POMZP3 | 22932 | 210910_s_at | 0.7031 | 0.3100 | |
| GSE77861 | POMZP3 | 22932 | 210910_s_at | 0.7906 | 0.1107 | |
| GSE97050 | POMZP3 | 22932 | A_33_P3412233 | 0.2331 | 0.4625 | |
| SRP007169 | POMZP3 | 22932 | RNAseq | -1.2817 | 0.0132 | |
| SRP008496 | POMZP3 | 22932 | RNAseq | -1.0050 | 0.0016 | |
| SRP064894 | POMZP3 | 22932 | RNAseq | 0.2064 | 0.5000 | |
| SRP133303 | POMZP3 | 22932 | RNAseq | 0.2796 | 0.2515 | |
| SRP159526 | POMZP3 | 22932 | RNAseq | 0.4153 | 0.1141 | |
| SRP193095 | POMZP3 | 22932 | RNAseq | 0.4202 | 0.0142 | |
| SRP219564 | POMZP3 | 22932 | RNAseq | -0.0659 | 0.8869 | |
| TCGA | POMZP3 | 22932 | RNAseq | 0.0893 | 0.3975 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by POMZP3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of POMZP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POMZP3 | 22932 | 15 | 1 | 14 | |
| GSE20123 | POMZP3 | 22932 | 15 | 1 | 14 | |
| GSE43470 | POMZP3 | 22932 | 3 | 2 | 38 | |
| GSE46452 | POMZP3 | 22932 | 11 | 0 | 48 | |
| GSE47630 | POMZP3 | 22932 | 7 | 3 | 30 | |
| GSE54993 | POMZP3 | 22932 | 2 | 7 | 61 | |
| GSE54994 | POMZP3 | 22932 | 15 | 3 | 35 | |
| GSE60625 | POMZP3 | 22932 | 0 | 0 | 11 | |
| GSE74703 | POMZP3 | 22932 | 3 | 1 | 32 | |
| GSE74704 | POMZP3 | 22932 | 8 | 1 | 11 | |
| TCGA | POMZP3 | 22932 | 44 | 5 | 47 |
Total number of gains: 123; Total number of losses: 24; Total Number of normals: 341.
Somatic mutations of POMZP3:
Generating mutation plots.
Highly correlated genes for POMZP3:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POMZP3 | MZT1 | 0.837943 | 3 | 0 | 3 |
| POMZP3 | USP28 | 0.782941 | 3 | 0 | 3 |
| POMZP3 | C12orf65 | 0.770772 | 3 | 0 | 3 |
| POMZP3 | CENPV | 0.76242 | 3 | 0 | 3 |
| POMZP3 | RICTOR | 0.759027 | 3 | 0 | 3 |
| POMZP3 | PTDSS2 | 0.754102 | 3 | 0 | 3 |
| POMZP3 | CBLL1 | 0.753674 | 3 | 0 | 3 |
| POMZP3 | CTBP2 | 0.749226 | 4 | 0 | 4 |
| POMZP3 | CERS5 | 0.741465 | 3 | 0 | 3 |
| POMZP3 | HIBADH | 0.740264 | 3 | 0 | 3 |
| POMZP3 | ZBTB2 | 0.737276 | 3 | 0 | 3 |
| POMZP3 | NOM1 | 0.730789 | 4 | 0 | 3 |
| POMZP3 | CREB5 | 0.728153 | 3 | 0 | 3 |
| POMZP3 | SLC37A3 | 0.723818 | 3 | 0 | 3 |
| POMZP3 | PPP2R2D | 0.720531 | 3 | 0 | 3 |
| POMZP3 | SFT2D3 | 0.719645 | 3 | 0 | 3 |
| POMZP3 | ZC3H12C | 0.719198 | 3 | 0 | 3 |
| POMZP3 | PDP1 | 0.719106 | 3 | 0 | 3 |
| POMZP3 | MRPL48 | 0.712487 | 3 | 0 | 3 |
| POMZP3 | WDR72 | 0.711243 | 3 | 0 | 3 |
For details and further investigation, click here
