| Full name: zinc finger and BTB domain containing 3 | Alias Symbol: FLJ23392 | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 79842 | HGNC ID: HGNC:22918 | Ensembl Gene: ENSG00000185670 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB3 | 79842 | 1553858_at | -0.1490 | 0.7140 | |
| GSE20347 | ZBTB3 | 79842 | 220391_at | -0.3477 | 0.0010 | |
| GSE23400 | ZBTB3 | 79842 | 220391_at | 0.0077 | 0.6908 | |
| GSE26886 | ZBTB3 | 79842 | 1553858_at | 0.5155 | 0.0149 | |
| GSE29001 | ZBTB3 | 79842 | 220391_at | -0.0739 | 0.8701 | |
| GSE38129 | ZBTB3 | 79842 | 220391_at | -0.3219 | 0.0011 | |
| GSE45670 | ZBTB3 | 79842 | 1553858_at | 0.1440 | 0.3193 | |
| GSE53622 | ZBTB3 | 79842 | 30976 | -0.0805 | 0.3053 | |
| GSE53624 | ZBTB3 | 79842 | 22446 | 0.0689 | 0.2170 | |
| GSE63941 | ZBTB3 | 79842 | 1553858_at | 0.0936 | 0.7477 | |
| GSE77861 | ZBTB3 | 79842 | 1553858_at | -0.0948 | 0.2536 | |
| GSE97050 | ZBTB3 | 79842 | A_23_P430181 | 0.2315 | 0.3143 | |
| SRP007169 | ZBTB3 | 79842 | RNAseq | 0.0420 | 0.9239 | |
| SRP008496 | ZBTB3 | 79842 | RNAseq | -0.1306 | 0.6520 | |
| SRP064894 | ZBTB3 | 79842 | RNAseq | 0.1225 | 0.5390 | |
| SRP133303 | ZBTB3 | 79842 | RNAseq | -0.0569 | 0.6626 | |
| SRP159526 | ZBTB3 | 79842 | RNAseq | -0.3517 | 0.2092 | |
| SRP193095 | ZBTB3 | 79842 | RNAseq | -0.1719 | 0.0355 | |
| SRP219564 | ZBTB3 | 79842 | RNAseq | 0.4011 | 0.2427 | |
| TCGA | ZBTB3 | 79842 | RNAseq | -0.3549 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB3 | 79842 | 6 | 5 | 19 | |
| GSE20123 | ZBTB3 | 79842 | 6 | 5 | 19 | |
| GSE43470 | ZBTB3 | 79842 | 1 | 6 | 36 | |
| GSE46452 | ZBTB3 | 79842 | 8 | 4 | 47 | |
| GSE47630 | ZBTB3 | 79842 | 3 | 7 | 30 | |
| GSE54993 | ZBTB3 | 79842 | 3 | 0 | 67 | |
| GSE54994 | ZBTB3 | 79842 | 4 | 5 | 44 | |
| GSE60625 | ZBTB3 | 79842 | 0 | 3 | 8 | |
| GSE74703 | ZBTB3 | 79842 | 1 | 3 | 32 | |
| GSE74704 | ZBTB3 | 79842 | 4 | 3 | 13 | |
| TCGA | ZBTB3 | 79842 | 12 | 11 | 73 |
Total number of gains: 48; Total number of losses: 52; Total Number of normals: 388.
Somatic mutations of ZBTB3:
Generating mutation plots.
Highly correlated genes for ZBTB3:
Showing all 18 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB3 | ZCCHC18 | 0.710678 | 3 | 0 | 3 |
| ZBTB3 | PPA2 | 0.700523 | 3 | 0 | 3 |
| ZBTB3 | ZNF852 | 0.684042 | 3 | 0 | 3 |
| ZBTB3 | MYL4 | 0.667386 | 3 | 0 | 3 |
| ZBTB3 | SERTM1 | 0.639271 | 3 | 0 | 3 |
| ZBTB3 | PRDM6 | 0.611928 | 3 | 0 | 3 |
| ZBTB3 | PAX8 | 0.590314 | 3 | 0 | 3 |
| ZBTB3 | YIPF5 | 0.585385 | 3 | 0 | 3 |
| ZBTB3 | CROT | 0.581385 | 3 | 0 | 3 |
| ZBTB3 | ZMYND12 | 0.576432 | 5 | 0 | 4 |
| ZBTB3 | FBXO34 | 0.574072 | 3 | 0 | 3 |
| ZBTB3 | ERCC5 | 0.573654 | 3 | 0 | 3 |
| ZBTB3 | PEX12 | 0.565723 | 4 | 0 | 3 |
| ZBTB3 | TDRD9 | 0.558869 | 4 | 0 | 3 |
| ZBTB3 | SCN5A | 0.556 | 3 | 0 | 3 |
| ZBTB3 | PHYHIP | 0.5528 | 4 | 0 | 3 |
| ZBTB3 | ZNF14 | 0.530608 | 4 | 0 | 3 |
| ZBTB3 | KIR2DS4 | 0.501689 | 4 | 0 | 3 |
For details and further investigation, click here
