| Full name: PR/SET domain 6 | Alias Symbol: PRISM|KMT8C | ||
| Type: protein-coding gene | Cytoband: 5q23.2 | ||
| Entrez ID: 93166 | HGNC ID: HGNC:9350 | Ensembl Gene: ENSG00000061455 | OMIM ID: 616982 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM6 | 93166 | 230311_s_at | -0.2877 | 0.3416 | |
| GSE26886 | PRDM6 | 93166 | 230311_s_at | 0.1908 | 0.2595 | |
| GSE45670 | PRDM6 | 93166 | 230311_s_at | -0.5681 | 0.0088 | |
| GSE53622 | PRDM6 | 93166 | 47762 | -0.5910 | 0.0019 | |
| GSE53624 | PRDM6 | 93166 | 47762 | -0.2362 | 0.1274 | |
| GSE63941 | PRDM6 | 93166 | 230311_s_at | -0.5434 | 0.1886 | |
| GSE77861 | PRDM6 | 93166 | 230311_s_at | 0.1268 | 0.3792 | |
| GSE97050 | PRDM6 | 93166 | A_32_P222684 | 0.0383 | 0.9326 | |
| SRP007169 | PRDM6 | 93166 | RNAseq | 1.8175 | 0.0853 | |
| SRP064894 | PRDM6 | 93166 | RNAseq | 0.0941 | 0.7628 | |
| SRP133303 | PRDM6 | 93166 | RNAseq | -0.4133 | 0.0600 | |
| SRP159526 | PRDM6 | 93166 | RNAseq | -0.7356 | 0.0794 | |
| SRP219564 | PRDM6 | 93166 | RNAseq | 0.7113 | 0.3097 | |
| TCGA | PRDM6 | 93166 | RNAseq | -0.5392 | 0.0170 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRDM6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM6 | 93166 | 1 | 13 | 16 | |
| GSE20123 | PRDM6 | 93166 | 1 | 13 | 16 | |
| GSE43470 | PRDM6 | 93166 | 3 | 8 | 32 | |
| GSE46452 | PRDM6 | 93166 | 0 | 27 | 32 | |
| GSE47630 | PRDM6 | 93166 | 0 | 21 | 19 | |
| GSE54993 | PRDM6 | 93166 | 9 | 1 | 60 | |
| GSE54994 | PRDM6 | 93166 | 2 | 14 | 37 | |
| GSE60625 | PRDM6 | 93166 | 0 | 0 | 11 | |
| GSE74703 | PRDM6 | 93166 | 2 | 6 | 28 | |
| GSE74704 | PRDM6 | 93166 | 1 | 7 | 12 | |
| TCGA | PRDM6 | 93166 | 2 | 41 | 53 |
Total number of gains: 21; Total number of losses: 151; Total Number of normals: 316.
Somatic mutations of PRDM6:
Generating mutation plots.
Highly correlated genes for PRDM6:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM6 | NRXN1 | 0.725656 | 3 | 0 | 3 |
| PRDM6 | ALDH8A1 | 0.708462 | 3 | 0 | 3 |
| PRDM6 | MAGEE2 | 0.696851 | 3 | 0 | 3 |
| PRDM6 | SHC2 | 0.649894 | 4 | 0 | 3 |
| PRDM6 | ALAS2 | 0.649016 | 3 | 0 | 3 |
| PRDM6 | GARNL3 | 0.648911 | 4 | 0 | 3 |
| PRDM6 | STAC2 | 0.645929 | 3 | 0 | 3 |
| PRDM6 | GSTM5 | 0.644069 | 4 | 0 | 3 |
| PRDM6 | TRAK2 | 0.63502 | 3 | 0 | 3 |
| PRDM6 | VIPR2 | 0.634412 | 5 | 0 | 3 |
| PRDM6 | SAMD4A | 0.63025 | 4 | 0 | 3 |
| PRDM6 | TPO | 0.626373 | 4 | 0 | 3 |
| PRDM6 | FSIP1 | 0.62464 | 4 | 0 | 3 |
| PRDM6 | PGPEP1 | 0.619971 | 6 | 0 | 4 |
| PRDM6 | NXPH3 | 0.615788 | 4 | 0 | 3 |
| PRDM6 | ZC3H6 | 0.615227 | 5 | 0 | 4 |
| PRDM6 | ZBTB3 | 0.611928 | 3 | 0 | 3 |
| PRDM6 | ATP6AP1L | 0.611583 | 5 | 0 | 3 |
| PRDM6 | OSBPL5 | 0.611572 | 4 | 0 | 3 |
| PRDM6 | RSPH4A | 0.607228 | 4 | 0 | 3 |
For details and further investigation, click here
