| Full name: zinc finger and BTB domain containing 41 | Alias Symbol: FRBZ1|FLJ36199|DKFZp686C06120|ZNF924 | ||
| Type: protein-coding gene | Cytoband: 1q31.3 | ||
| Entrez ID: 360023 | HGNC ID: HGNC:24819 | Ensembl Gene: ENSG00000177888 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB41:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB41 | 360023 | 226962_at | 0.7175 | 0.0294 | |
| GSE26886 | ZBTB41 | 360023 | 226962_at | 0.8195 | 0.0030 | |
| GSE45670 | ZBTB41 | 360023 | 226962_at | 0.2324 | 0.2882 | |
| GSE53622 | ZBTB41 | 360023 | 15106 | 0.3537 | 0.0004 | |
| GSE53624 | ZBTB41 | 360023 | 19955 | 0.5773 | 0.0000 | |
| GSE63941 | ZBTB41 | 360023 | 226962_at | -0.8678 | 0.0920 | |
| GSE77861 | ZBTB41 | 360023 | 226962_at | 0.9846 | 0.0063 | |
| GSE97050 | ZBTB41 | 360023 | A_32_P108826 | 0.0222 | 0.9234 | |
| SRP007169 | ZBTB41 | 360023 | RNAseq | 0.9726 | 0.0215 | |
| SRP008496 | ZBTB41 | 360023 | RNAseq | 1.2427 | 0.0002 | |
| SRP064894 | ZBTB41 | 360023 | RNAseq | 0.4897 | 0.0602 | |
| SRP133303 | ZBTB41 | 360023 | RNAseq | 0.6953 | 0.0000 | |
| SRP159526 | ZBTB41 | 360023 | RNAseq | 0.5663 | 0.1162 | |
| SRP193095 | ZBTB41 | 360023 | RNAseq | 0.2598 | 0.0608 | |
| SRP219564 | ZBTB41 | 360023 | RNAseq | 0.3701 | 0.3011 | |
| TCGA | ZBTB41 | 360023 | RNAseq | 0.0778 | 0.2047 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZBTB41 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB41:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB41 | 360023 | 6 | 1 | 23 | |
| GSE20123 | ZBTB41 | 360023 | 6 | 1 | 23 | |
| GSE43470 | ZBTB41 | 360023 | 5 | 1 | 37 | |
| GSE46452 | ZBTB41 | 360023 | 3 | 1 | 55 | |
| GSE47630 | ZBTB41 | 360023 | 14 | 0 | 26 | |
| GSE54993 | ZBTB41 | 360023 | 0 | 6 | 64 | |
| GSE54994 | ZBTB41 | 360023 | 16 | 0 | 37 | |
| GSE60625 | ZBTB41 | 360023 | 0 | 0 | 11 | |
| GSE74703 | ZBTB41 | 360023 | 5 | 1 | 30 | |
| GSE74704 | ZBTB41 | 360023 | 2 | 1 | 17 | |
| TCGA | ZBTB41 | 360023 | 41 | 6 | 49 |
Total number of gains: 98; Total number of losses: 18; Total Number of normals: 372.
Somatic mutations of ZBTB41:
Generating mutation plots.
Highly correlated genes for ZBTB41:
Showing top 20/1312 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB41 | CDCA2 | 0.794193 | 3 | 0 | 3 |
| ZBTB41 | KIAA0100 | 0.784964 | 3 | 0 | 3 |
| ZBTB41 | CENPBD1 | 0.768975 | 3 | 0 | 3 |
| ZBTB41 | ZDHHC17 | 0.762649 | 4 | 0 | 4 |
| ZBTB41 | SENP1 | 0.75258 | 3 | 0 | 3 |
| ZBTB41 | TMEM201 | 0.742547 | 3 | 0 | 3 |
| ZBTB41 | DFFA | 0.741636 | 3 | 0 | 3 |
| ZBTB41 | SLC38A6 | 0.741595 | 5 | 0 | 5 |
| ZBTB41 | LMNB2 | 0.738144 | 3 | 0 | 3 |
| ZBTB41 | ACVR1C | 0.732317 | 4 | 0 | 4 |
| ZBTB41 | TUBA1B | 0.730318 | 3 | 0 | 3 |
| ZBTB41 | NOL9 | 0.725484 | 4 | 0 | 4 |
| ZBTB41 | DSCC1 | 0.724786 | 4 | 0 | 3 |
| ZBTB41 | ACBD6 | 0.722088 | 6 | 0 | 6 |
| ZBTB41 | JADE2 | 0.721649 | 4 | 0 | 3 |
| ZBTB41 | KLF13 | 0.720146 | 4 | 0 | 4 |
| ZBTB41 | NAA25 | 0.719846 | 3 | 0 | 3 |
| ZBTB41 | BORA | 0.718436 | 4 | 0 | 3 |
| ZBTB41 | MAPKAPK5 | 0.718248 | 5 | 0 | 4 |
| ZBTB41 | PPP1R16A | 0.717777 | 3 | 0 | 3 |
For details and further investigation, click here
