| Full name: jade family PHD finger 2 | Alias Symbol: KIAA0239|JADE-2 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 23338 | HGNC ID: HGNC:22984 | Ensembl Gene: ENSG00000043143 | OMIM ID: 610515 |
| Drug and gene relationship at DGIdb | |||
Expression of JADE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JADE2 | 23338 | 212660_at | 1.3730 | 0.0947 | |
| GSE20347 | JADE2 | 23338 | 212660_at | 1.3526 | 0.0000 | |
| GSE23400 | JADE2 | 23338 | 212660_at | 0.6842 | 0.0000 | |
| GSE26886 | JADE2 | 23338 | 212660_at | 0.7340 | 0.0609 | |
| GSE29001 | JADE2 | 23338 | 212660_at | 1.4291 | 0.0007 | |
| GSE38129 | JADE2 | 23338 | 212660_at | 0.9171 | 0.0004 | |
| GSE45670 | JADE2 | 23338 | 212660_at | 0.3454 | 0.3001 | |
| GSE53622 | JADE2 | 23338 | 23536 | 0.4955 | 0.0001 | |
| GSE53624 | JADE2 | 23338 | 23536 | 1.0821 | 0.0000 | |
| GSE63941 | JADE2 | 23338 | 212660_at | 0.8871 | 0.2572 | |
| GSE77861 | JADE2 | 23338 | 212660_at | 2.1526 | 0.0006 | |
| SRP007169 | JADE2 | 23338 | RNAseq | 2.5574 | 0.0064 | |
| SRP008496 | JADE2 | 23338 | RNAseq | 3.4914 | 0.0000 | |
| SRP064894 | JADE2 | 23338 | RNAseq | 0.8411 | 0.0003 | |
| SRP133303 | JADE2 | 23338 | RNAseq | 0.7329 | 0.0047 | |
| SRP159526 | JADE2 | 23338 | RNAseq | 1.9428 | 0.0000 | |
| SRP193095 | JADE2 | 23338 | RNAseq | 1.5904 | 0.0000 | |
| SRP219564 | JADE2 | 23338 | RNAseq | 0.7581 | 0.0916 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by JADE2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of JADE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JADE2 | 23338 | 2 | 11 | 17 | |
| GSE20123 | JADE2 | 23338 | 3 | 11 | 16 | |
| GSE43470 | JADE2 | 23338 | 2 | 8 | 33 | |
| GSE46452 | JADE2 | 23338 | 0 | 27 | 32 | |
| GSE47630 | JADE2 | 23338 | 0 | 21 | 19 | |
| GSE54993 | JADE2 | 23338 | 9 | 1 | 60 | |
| GSE54994 | JADE2 | 23338 | 2 | 14 | 37 | |
| GSE60625 | JADE2 | 23338 | 0 | 0 | 11 | |
| GSE74703 | JADE2 | 23338 | 2 | 5 | 29 | |
| GSE74704 | JADE2 | 23338 | 2 | 5 | 13 |
Total number of gains: 22; Total number of losses: 103; Total Number of normals: 267.
Somatic mutations of JADE2:
Generating mutation plots.
Highly correlated genes for JADE2:
Showing top 20/827 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JADE2 | LRRC58 | 0.773043 | 3 | 0 | 3 |
| JADE2 | UHRF1 | 0.744733 | 3 | 0 | 3 |
| JADE2 | ZBTB41 | 0.721649 | 4 | 0 | 3 |
| JADE2 | SDCCAG8 | 0.717988 | 4 | 0 | 4 |
| JADE2 | BORA | 0.693285 | 3 | 0 | 3 |
| JADE2 | NUF2 | 0.673121 | 3 | 0 | 3 |
| JADE2 | HPS3 | 0.668108 | 4 | 0 | 3 |
| JADE2 | CLSPN | 0.665587 | 4 | 0 | 3 |
| JADE2 | BIRC5 | 0.66273 | 5 | 0 | 5 |
| JADE2 | GORAB | 0.658914 | 4 | 0 | 3 |
| JADE2 | DTL | 0.656106 | 6 | 0 | 5 |
| JADE2 | SLC38A6 | 0.650795 | 7 | 0 | 6 |
| JADE2 | TIGD7 | 0.64922 | 3 | 0 | 3 |
| JADE2 | EN1 | 0.649038 | 4 | 0 | 3 |
| JADE2 | FLVCR1 | 0.647609 | 4 | 0 | 4 |
| JADE2 | SMYD5 | 0.647478 | 4 | 0 | 3 |
| JADE2 | FAM131A | 0.64733 | 3 | 0 | 3 |
| JADE2 | ACBD6 | 0.645792 | 4 | 0 | 3 |
| JADE2 | PARP1 | 0.643611 | 9 | 0 | 8 |
| JADE2 | SLC41A1 | 0.640792 | 4 | 0 | 4 |
For details and further investigation, click here
