| Full name: zinc finger CCCH-type containing 4 | Alias Symbol: KIAA1064 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 23211 | HGNC ID: HGNC:17808 | Ensembl Gene: ENSG00000130749 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZC3H4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZC3H4 | 23211 | 213390_at | 0.0043 | 0.9916 | |
| GSE20347 | ZC3H4 | 23211 | 213390_at | -0.1668 | 0.1624 | |
| GSE23400 | ZC3H4 | 23211 | 213390_at | -0.0087 | 0.8985 | |
| GSE26886 | ZC3H4 | 23211 | 213390_at | -0.1090 | 0.6050 | |
| GSE29001 | ZC3H4 | 23211 | 213390_at | -0.0763 | 0.7685 | |
| GSE38129 | ZC3H4 | 23211 | 213390_at | -0.1173 | 0.1601 | |
| GSE45670 | ZC3H4 | 23211 | 213390_at | 0.0186 | 0.8907 | |
| GSE63941 | ZC3H4 | 23211 | 213390_at | 0.5831 | 0.0260 | |
| GSE77861 | ZC3H4 | 23211 | 213390_at | 0.0982 | 0.5587 | |
| GSE97050 | ZC3H4 | 23211 | A_24_P220618 | -0.2306 | 0.3710 | |
| SRP007169 | ZC3H4 | 23211 | RNAseq | 0.5420 | 0.1490 | |
| SRP008496 | ZC3H4 | 23211 | RNAseq | 0.5156 | 0.0482 | |
| SRP064894 | ZC3H4 | 23211 | RNAseq | -0.2549 | 0.1201 | |
| SRP133303 | ZC3H4 | 23211 | RNAseq | -0.0558 | 0.7019 | |
| SRP159526 | ZC3H4 | 23211 | RNAseq | 0.0379 | 0.8917 | |
| SRP193095 | ZC3H4 | 23211 | RNAseq | 0.1094 | 0.3877 | |
| SRP219564 | ZC3H4 | 23211 | RNAseq | -0.4371 | 0.1168 | |
| TCGA | ZC3H4 | 23211 | RNAseq | -0.0007 | 0.9884 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZC3H4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZC3H4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZC3H4 | 23211 | 4 | 4 | 22 | |
| GSE20123 | ZC3H4 | 23211 | 4 | 3 | 23 | |
| GSE43470 | ZC3H4 | 23211 | 3 | 11 | 29 | |
| GSE46452 | ZC3H4 | 23211 | 45 | 1 | 13 | |
| GSE47630 | ZC3H4 | 23211 | 8 | 7 | 25 | |
| GSE54993 | ZC3H4 | 23211 | 17 | 4 | 49 | |
| GSE54994 | ZC3H4 | 23211 | 4 | 14 | 35 | |
| GSE60625 | ZC3H4 | 23211 | 9 | 0 | 2 | |
| GSE74703 | ZC3H4 | 23211 | 3 | 7 | 26 | |
| GSE74704 | ZC3H4 | 23211 | 4 | 1 | 15 | |
| TCGA | ZC3H4 | 23211 | 15 | 18 | 63 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of ZC3H4:
Generating mutation plots.
Highly correlated genes for ZC3H4:
Showing top 20/202 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZC3H4 | CA11 | 0.789746 | 3 | 0 | 3 |
| ZC3H4 | ZNF613 | 0.725133 | 3 | 0 | 3 |
| ZC3H4 | EXOC6 | 0.703337 | 3 | 0 | 3 |
| ZC3H4 | PHIP | 0.699229 | 3 | 0 | 3 |
| ZC3H4 | ZFP37 | 0.696446 | 3 | 0 | 3 |
| ZC3H4 | ZNF10 | 0.69511 | 3 | 0 | 3 |
| ZC3H4 | CCNL1 | 0.67999 | 3 | 0 | 3 |
| ZC3H4 | ZNF614 | 0.679201 | 4 | 0 | 3 |
| ZC3H4 | USP10 | 0.676574 | 3 | 0 | 3 |
| ZC3H4 | SNAPC2 | 0.674109 | 3 | 0 | 3 |
| ZC3H4 | AFTPH | 0.667418 | 3 | 0 | 3 |
| ZC3H4 | SLC6A8 | 0.664702 | 3 | 0 | 3 |
| ZC3H4 | PPM1A | 0.663339 | 3 | 0 | 3 |
| ZC3H4 | RBBP7 | 0.663282 | 3 | 0 | 3 |
| ZC3H4 | ANP32B | 0.659699 | 4 | 0 | 3 |
| ZC3H4 | ASXL1 | 0.654681 | 3 | 0 | 3 |
| ZC3H4 | ZNF317 | 0.649547 | 5 | 0 | 5 |
| ZC3H4 | TMCO4 | 0.648232 | 4 | 0 | 3 |
| ZC3H4 | ALG12 | 0.642602 | 4 | 0 | 3 |
| ZC3H4 | HDAC6 | 0.640931 | 3 | 0 | 3 |
For details and further investigation, click here
