| Full name: acidic nuclear phosphoprotein 32 family member B | Alias Symbol: SSP29|PHAPI2|APRIL | ||
| Type: protein-coding gene | Cytoband: 9q22.33 | ||
| Entrez ID: 10541 | HGNC ID: HGNC:16677 | Ensembl Gene: ENSG00000136938 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ANP32B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANP32B | 10541 | 201306_s_at | 0.1215 | 0.5643 | |
| GSE20347 | ANP32B | 10541 | 201306_s_at | 0.4160 | 0.0017 | |
| GSE23400 | ANP32B | 10541 | 201306_s_at | 0.4364 | 0.0000 | |
| GSE26886 | ANP32B | 10541 | 201306_s_at | 0.5052 | 0.0005 | |
| GSE29001 | ANP32B | 10541 | 201306_s_at | 0.4893 | 0.0034 | |
| GSE38129 | ANP32B | 10541 | 201306_s_at | 0.4204 | 0.0000 | |
| GSE45670 | ANP32B | 10541 | 201306_s_at | -0.0129 | 0.9363 | |
| GSE53622 | ANP32B | 10541 | 41357 | 0.3258 | 0.0000 | |
| GSE53624 | ANP32B | 10541 | 41357 | 0.4475 | 0.0000 | |
| GSE63941 | ANP32B | 10541 | 201306_s_at | 1.6876 | 0.0000 | |
| GSE77861 | ANP32B | 10541 | 201306_s_at | 0.4330 | 0.0145 | |
| GSE97050 | ANP32B | 10541 | A_23_P20615 | -0.0232 | 0.9307 | |
| SRP007169 | ANP32B | 10541 | RNAseq | 1.1334 | 0.0019 | |
| SRP008496 | ANP32B | 10541 | RNAseq | 1.1702 | 0.0000 | |
| SRP064894 | ANP32B | 10541 | RNAseq | 0.6324 | 0.0054 | |
| SRP133303 | ANP32B | 10541 | RNAseq | 0.1509 | 0.1807 | |
| SRP159526 | ANP32B | 10541 | RNAseq | 0.4470 | 0.1711 | |
| SRP193095 | ANP32B | 10541 | RNAseq | 0.2423 | 0.0803 | |
| SRP219564 | ANP32B | 10541 | RNAseq | 0.3723 | 0.2861 | |
| TCGA | ANP32B | 10541 | RNAseq | 0.1275 | 0.0053 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ANP32B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANP32B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANP32B | 10541 | 7 | 8 | 15 | |
| GSE20123 | ANP32B | 10541 | 7 | 7 | 16 | |
| GSE43470 | ANP32B | 10541 | 6 | 3 | 34 | |
| GSE46452 | ANP32B | 10541 | 6 | 14 | 39 | |
| GSE47630 | ANP32B | 10541 | 1 | 17 | 22 | |
| GSE54993 | ANP32B | 10541 | 3 | 3 | 64 | |
| GSE54994 | ANP32B | 10541 | 8 | 11 | 34 | |
| GSE60625 | ANP32B | 10541 | 0 | 0 | 11 | |
| GSE74703 | ANP32B | 10541 | 5 | 3 | 28 | |
| GSE74704 | ANP32B | 10541 | 3 | 5 | 12 | |
| TCGA | ANP32B | 10541 | 27 | 22 | 47 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of ANP32B:
Generating mutation plots.
Highly correlated genes for ANP32B:
Showing top 20/1466 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANP32B | MOB3A | 0.807295 | 3 | 0 | 3 |
| ANP32B | SPTAN1 | 0.802334 | 3 | 0 | 3 |
| ANP32B | C2orf69 | 0.794435 | 3 | 0 | 3 |
| ANP32B | ZNF567 | 0.766086 | 3 | 0 | 3 |
| ANP32B | ZNF579 | 0.76557 | 3 | 0 | 3 |
| ANP32B | RHOB | 0.757214 | 3 | 0 | 3 |
| ANP32B | ZFP90 | 0.756832 | 3 | 0 | 3 |
| ANP32B | NR1H2 | 0.756209 | 3 | 0 | 3 |
| ANP32B | NFIB | 0.754771 | 3 | 0 | 3 |
| ANP32B | CPT1A | 0.752521 | 3 | 0 | 3 |
| ANP32B | ZNF362 | 0.74751 | 4 | 0 | 4 |
| ANP32B | MIER2 | 0.745459 | 3 | 0 | 3 |
| ANP32B | CCNT1 | 0.743005 | 4 | 0 | 4 |
| ANP32B | NOTCH3 | 0.739853 | 3 | 0 | 3 |
| ANP32B | COMMD7 | 0.739317 | 3 | 0 | 3 |
| ANP32B | WDR54 | 0.736128 | 5 | 0 | 5 |
| ANP32B | NACC1 | 0.732275 | 4 | 0 | 4 |
| ANP32B | TRPM4 | 0.729861 | 3 | 0 | 3 |
| ANP32B | AKR1E2 | 0.723309 | 3 | 0 | 3 |
| ANP32B | DYRK2 | 0.72235 | 3 | 0 | 3 |
For details and further investigation, click here
