| Full name: ubiquitin specific peptidase 10 | Alias Symbol: UBPO|KIAA0190 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 9100 | HGNC ID: HGNC:12608 | Ensembl Gene: ENSG00000103194 | OMIM ID: 609818 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of USP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP10 | 9100 | 209137_s_at | 0.4520 | 0.0997 | |
| GSE20347 | USP10 | 9100 | 209137_s_at | 0.3359 | 0.0222 | |
| GSE23400 | USP10 | 9100 | 209137_s_at | 0.4390 | 0.0000 | |
| GSE26886 | USP10 | 9100 | 209137_s_at | -0.0904 | 0.6687 | |
| GSE29001 | USP10 | 9100 | 209137_s_at | 0.5043 | 0.1353 | |
| GSE38129 | USP10 | 9100 | 209137_s_at | 0.4512 | 0.0000 | |
| GSE45670 | USP10 | 9100 | 209137_s_at | 0.4686 | 0.0005 | |
| GSE53622 | USP10 | 9100 | 100654 | 0.6462 | 0.0000 | |
| GSE53624 | USP10 | 9100 | 100654 | 0.8177 | 0.0000 | |
| GSE63941 | USP10 | 9100 | 209137_s_at | 1.9823 | 0.0000 | |
| GSE77861 | USP10 | 9100 | 209137_s_at | 0.6483 | 0.0114 | |
| GSE97050 | USP10 | 9100 | A_32_P26330 | 0.3810 | 0.1420 | |
| SRP007169 | USP10 | 9100 | RNAseq | 0.8571 | 0.0052 | |
| SRP008496 | USP10 | 9100 | RNAseq | 0.7039 | 0.0167 | |
| SRP064894 | USP10 | 9100 | RNAseq | 0.1679 | 0.1802 | |
| SRP133303 | USP10 | 9100 | RNAseq | 0.7182 | 0.0002 | |
| SRP159526 | USP10 | 9100 | RNAseq | 0.5882 | 0.0252 | |
| SRP193095 | USP10 | 9100 | RNAseq | 0.4504 | 0.0000 | |
| SRP219564 | USP10 | 9100 | RNAseq | 0.1626 | 0.4928 | |
| TCGA | USP10 | 9100 | RNAseq | 0.1296 | 0.0035 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by USP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP10 | 9100 | 4 | 5 | 21 | |
| GSE20123 | USP10 | 9100 | 4 | 5 | 21 | |
| GSE43470 | USP10 | 9100 | 2 | 10 | 31 | |
| GSE46452 | USP10 | 9100 | 37 | 2 | 20 | |
| GSE47630 | USP10 | 9100 | 11 | 9 | 20 | |
| GSE54993 | USP10 | 9100 | 3 | 4 | 63 | |
| GSE54994 | USP10 | 9100 | 8 | 10 | 35 | |
| GSE60625 | USP10 | 9100 | 4 | 0 | 7 | |
| GSE74703 | USP10 | 9100 | 2 | 7 | 27 | |
| GSE74704 | USP10 | 9100 | 3 | 3 | 14 | |
| TCGA | USP10 | 9100 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 71; Total Number of normals: 313.
Somatic mutations of USP10:
Generating mutation plots.
Highly correlated genes for USP10:
Showing top 20/1540 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP10 | CCDC124 | 0.782058 | 3 | 0 | 3 |
| USP10 | EFTUD2 | 0.769663 | 7 | 0 | 7 |
| USP10 | ZC3H18 | 0.746175 | 5 | 0 | 4 |
| USP10 | C1orf56 | 0.744795 | 3 | 0 | 3 |
| USP10 | SIX4 | 0.74328 | 6 | 0 | 6 |
| USP10 | PTCD1 | 0.735207 | 3 | 0 | 3 |
| USP10 | FADS1 | 0.729076 | 3 | 0 | 3 |
| USP10 | EMC8 | 0.727312 | 10 | 0 | 10 |
| USP10 | STK35 | 0.726319 | 3 | 0 | 3 |
| USP10 | BOLA3 | 0.724935 | 5 | 0 | 5 |
| USP10 | NUF2 | 0.719504 | 7 | 0 | 7 |
| USP10 | TMEM41A | 0.719011 | 3 | 0 | 3 |
| USP10 | CTU2 | 0.71832 | 5 | 0 | 5 |
| USP10 | FAM89A | 0.717225 | 3 | 0 | 3 |
| USP10 | RAB34 | 0.713995 | 3 | 0 | 3 |
| USP10 | CMSS1 | 0.709705 | 6 | 0 | 6 |
| USP10 | EBNA1BP2 | 0.70641 | 3 | 0 | 3 |
| USP10 | NOP56 | 0.703158 | 3 | 0 | 3 |
| USP10 | TMEM205 | 0.698188 | 3 | 0 | 3 |
| USP10 | NUP93 | 0.697556 | 10 | 0 | 9 |
For details and further investigation, click here
