| Full name: carbonic anhydrase 11 | Alias Symbol: CARP2|CARPX1 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 770 | HGNC ID: HGNC:1370 | Ensembl Gene: ENSG00000063180 | OMIM ID: 604644 |
| Drug and gene relationship at DGIdb | |||
Expression of CA11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CA11 | 770 | 209726_at | -0.4997 | 0.5762 | |
| GSE20347 | CA11 | 770 | 209726_at | 0.0036 | 0.9810 | |
| GSE23400 | CA11 | 770 | 209726_at | -0.0151 | 0.7898 | |
| GSE26886 | CA11 | 770 | 209726_at | 0.3383 | 0.1930 | |
| GSE29001 | CA11 | 770 | 209726_at | -0.0138 | 0.9593 | |
| GSE38129 | CA11 | 770 | 209726_at | -0.0309 | 0.9141 | |
| GSE45670 | CA11 | 770 | 209726_at | -0.1350 | 0.5322 | |
| GSE53622 | CA11 | 770 | 76637 | -0.0082 | 0.9480 | |
| GSE53624 | CA11 | 770 | 76637 | 0.0781 | 0.3708 | |
| GSE63941 | CA11 | 770 | 209726_at | 1.9409 | 0.0284 | |
| GSE77861 | CA11 | 770 | 209726_at | 0.2354 | 0.1809 | |
| GSE97050 | CA11 | 770 | A_23_P78782 | -0.2085 | 0.6367 | |
| SRP064894 | CA11 | 770 | RNAseq | 0.3600 | 0.3543 | |
| SRP133303 | CA11 | 770 | RNAseq | -0.0829 | 0.7262 | |
| SRP159526 | CA11 | 770 | RNAseq | -0.2366 | 0.5451 | |
| SRP193095 | CA11 | 770 | RNAseq | 0.0970 | 0.6901 | |
| SRP219564 | CA11 | 770 | RNAseq | -0.4644 | 0.5089 | |
| TCGA | CA11 | 770 | RNAseq | -0.1715 | 0.2384 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CA11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CA11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CA11 | 770 | 4 | 4 | 22 | |
| GSE20123 | CA11 | 770 | 4 | 3 | 23 | |
| GSE43470 | CA11 | 770 | 4 | 10 | 29 | |
| GSE46452 | CA11 | 770 | 45 | 1 | 13 | |
| GSE47630 | CA11 | 770 | 8 | 7 | 25 | |
| GSE54993 | CA11 | 770 | 17 | 4 | 49 | |
| GSE54994 | CA11 | 770 | 4 | 14 | 35 | |
| GSE60625 | CA11 | 770 | 9 | 0 | 2 | |
| GSE74703 | CA11 | 770 | 4 | 7 | 25 | |
| GSE74704 | CA11 | 770 | 4 | 1 | 15 | |
| TCGA | CA11 | 770 | 14 | 18 | 64 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of CA11:
Generating mutation plots.
Highly correlated genes for CA11:
Showing top 20/293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CA11 | ZC3H4 | 0.789746 | 3 | 0 | 3 |
| CA11 | EPDR1 | 0.756243 | 3 | 0 | 3 |
| CA11 | APLP2 | 0.754596 | 3 | 0 | 3 |
| CA11 | CLYBL | 0.719343 | 3 | 0 | 3 |
| CA11 | RPRD2 | 0.707027 | 3 | 0 | 3 |
| CA11 | NFIB | 0.702929 | 3 | 0 | 3 |
| CA11 | HSPA6 | 0.698939 | 3 | 0 | 3 |
| CA11 | MACROD2 | 0.695822 | 3 | 0 | 3 |
| CA11 | RNF150 | 0.693727 | 3 | 0 | 3 |
| CA11 | BEND5 | 0.693254 | 3 | 0 | 3 |
| CA11 | DAPK1 | 0.68414 | 5 | 0 | 4 |
| CA11 | VIPR1 | 0.67858 | 3 | 0 | 3 |
| CA11 | CCDC136 | 0.666981 | 4 | 0 | 4 |
| CA11 | MZF1 | 0.665751 | 3 | 0 | 3 |
| CA11 | MPPED2 | 0.66308 | 3 | 0 | 3 |
| CA11 | SOX5 | 0.661189 | 3 | 0 | 3 |
| CA11 | TLN2 | 0.65925 | 4 | 0 | 3 |
| CA11 | STOX1 | 0.656168 | 4 | 0 | 3 |
| CA11 | LIFR | 0.654603 | 3 | 0 | 3 |
| CA11 | EEF1D | 0.653066 | 3 | 0 | 3 |
For details and further investigation, click here
