| Full name: cyclin L1 | Alias Symbol: ania-6a | ||
| Type: protein-coding gene | Cytoband: 3q25.31 | ||
| Entrez ID: 57018 | HGNC ID: HGNC:20569 | Ensembl Gene: ENSG00000163660 | OMIM ID: 613384 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCNL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCNL1 | 57018 | 220046_s_at | -0.0061 | 0.9954 | |
| GSE20347 | CCNL1 | 57018 | 220046_s_at | 0.7454 | 0.0000 | |
| GSE23400 | CCNL1 | 57018 | 220046_s_at | 0.4015 | 0.0000 | |
| GSE26886 | CCNL1 | 57018 | 220046_s_at | -0.0899 | 0.7478 | |
| GSE29001 | CCNL1 | 57018 | 220046_s_at | 0.5211 | 0.0655 | |
| GSE38129 | CCNL1 | 57018 | 220046_s_at | 0.4712 | 0.0407 | |
| GSE45670 | CCNL1 | 57018 | 1555411_a_at | 0.2594 | 0.2066 | |
| GSE53622 | CCNL1 | 57018 | 12334 | 0.5402 | 0.0000 | |
| GSE53624 | CCNL1 | 57018 | 12334 | 0.3666 | 0.0000 | |
| GSE63941 | CCNL1 | 57018 | 1555411_a_at | 0.7334 | 0.1226 | |
| GSE77861 | CCNL1 | 57018 | 220046_s_at | 0.7491 | 0.0061 | |
| GSE97050 | CCNL1 | 57018 | A_33_P3347928 | 0.0998 | 0.7673 | |
| SRP007169 | CCNL1 | 57018 | RNAseq | 0.0847 | 0.8095 | |
| SRP008496 | CCNL1 | 57018 | RNAseq | 0.1559 | 0.5046 | |
| SRP064894 | CCNL1 | 57018 | RNAseq | 0.1655 | 0.4998 | |
| SRP133303 | CCNL1 | 57018 | RNAseq | 0.5076 | 0.0212 | |
| SRP159526 | CCNL1 | 57018 | RNAseq | 0.5344 | 0.0503 | |
| SRP193095 | CCNL1 | 57018 | RNAseq | 0.4784 | 0.0024 | |
| SRP219564 | CCNL1 | 57018 | RNAseq | 0.0413 | 0.9045 | |
| TCGA | CCNL1 | 57018 | RNAseq | 0.1143 | 0.0434 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCNL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCNL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCNL1 | 57018 | 21 | 1 | 8 | |
| GSE20123 | CCNL1 | 57018 | 21 | 1 | 8 | |
| GSE43470 | CCNL1 | 57018 | 23 | 0 | 20 | |
| GSE46452 | CCNL1 | 57018 | 18 | 2 | 39 | |
| GSE47630 | CCNL1 | 57018 | 19 | 3 | 18 | |
| GSE54993 | CCNL1 | 57018 | 1 | 11 | 58 | |
| GSE54994 | CCNL1 | 57018 | 38 | 1 | 14 | |
| GSE60625 | CCNL1 | 57018 | 0 | 6 | 5 | |
| GSE74703 | CCNL1 | 57018 | 20 | 0 | 16 | |
| GSE74704 | CCNL1 | 57018 | 14 | 0 | 6 | |
| TCGA | CCNL1 | 57018 | 75 | 1 | 20 |
Total number of gains: 250; Total number of losses: 26; Total Number of normals: 212.
Somatic mutations of CCNL1:
Generating mutation plots.
Highly correlated genes for CCNL1:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCNL1 | JUND | 0.76292 | 3 | 0 | 3 |
| CCNL1 | SCRN1 | 0.709598 | 4 | 0 | 4 |
| CCNL1 | RHOB | 0.681113 | 3 | 0 | 3 |
| CCNL1 | ZC3H4 | 0.67999 | 3 | 0 | 3 |
| CCNL1 | COL4A5 | 0.678169 | 5 | 0 | 4 |
| CCNL1 | PRNP | 0.670427 | 4 | 0 | 3 |
| CCNL1 | LENG8 | 0.662929 | 3 | 0 | 3 |
| CCNL1 | KIF13A | 0.662658 | 4 | 0 | 4 |
| CCNL1 | SRSF4 | 0.651695 | 3 | 0 | 3 |
| CCNL1 | KIAA1324L | 0.636664 | 3 | 0 | 3 |
| CCNL1 | STX16 | 0.635524 | 7 | 0 | 6 |
| CCNL1 | TTC7B | 0.631893 | 3 | 0 | 3 |
| CCNL1 | NOM1 | 0.626677 | 3 | 0 | 3 |
| CCNL1 | U2SURP | 0.621891 | 8 | 0 | 7 |
| CCNL1 | DVL3 | 0.618421 | 9 | 0 | 8 |
| CCNL1 | PRSS23 | 0.613827 | 4 | 0 | 3 |
| CCNL1 | IFNGR1 | 0.611818 | 6 | 0 | 4 |
| CCNL1 | SUGP2 | 0.609982 | 3 | 0 | 3 |
| CCNL1 | PHLDB2 | 0.607398 | 5 | 0 | 5 |
| CCNL1 | KDM6B | 0.605848 | 5 | 0 | 5 |
For details and further investigation, click here
