| Full name: zinc finger CCHC-type containing 14 | Alias Symbol: BDG29|MGC14139 | ||
| Type: protein-coding gene | Cytoband: 16q24.2 | ||
| Entrez ID: 23174 | HGNC ID: HGNC:24134 | Ensembl Gene: ENSG00000140948 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZCCHC14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZCCHC14 | 23174 | 212655_at | 0.3465 | 0.3227 | |
| GSE20347 | ZCCHC14 | 23174 | 212655_at | 0.5120 | 0.0005 | |
| GSE23400 | ZCCHC14 | 23174 | 212655_at | 0.5152 | 0.0000 | |
| GSE26886 | ZCCHC14 | 23174 | 212655_at | -0.1409 | 0.7244 | |
| GSE29001 | ZCCHC14 | 23174 | 212655_at | 0.3480 | 0.2552 | |
| GSE38129 | ZCCHC14 | 23174 | 212655_at | 0.3776 | 0.0051 | |
| GSE45670 | ZCCHC14 | 23174 | 212655_at | -0.1905 | 0.2186 | |
| GSE53622 | ZCCHC14 | 23174 | 61160 | 0.3627 | 0.0000 | |
| GSE53624 | ZCCHC14 | 23174 | 61160 | 0.4814 | 0.0000 | |
| GSE63941 | ZCCHC14 | 23174 | 212655_at | -1.1459 | 0.0118 | |
| GSE77861 | ZCCHC14 | 23174 | 212655_at | 0.3663 | 0.0780 | |
| GSE97050 | ZCCHC14 | 23174 | A_23_P100420 | -0.3800 | 0.1791 | |
| SRP007169 | ZCCHC14 | 23174 | RNAseq | 1.3561 | 0.0005 | |
| SRP008496 | ZCCHC14 | 23174 | RNAseq | 1.5826 | 0.0000 | |
| SRP064894 | ZCCHC14 | 23174 | RNAseq | 0.0801 | 0.7327 | |
| SRP133303 | ZCCHC14 | 23174 | RNAseq | 0.6266 | 0.0085 | |
| SRP159526 | ZCCHC14 | 23174 | RNAseq | 0.2988 | 0.3679 | |
| SRP193095 | ZCCHC14 | 23174 | RNAseq | 0.2878 | 0.0017 | |
| SRP219564 | ZCCHC14 | 23174 | RNAseq | 0.0354 | 0.8669 | |
| TCGA | ZCCHC14 | 23174 | RNAseq | -0.0576 | 0.2239 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by ZCCHC14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZCCHC14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZCCHC14 | 23174 | 4 | 2 | 24 | |
| GSE20123 | ZCCHC14 | 23174 | 4 | 2 | 24 | |
| GSE43470 | ZCCHC14 | 23174 | 1 | 13 | 29 | |
| GSE46452 | ZCCHC14 | 23174 | 38 | 1 | 20 | |
| GSE47630 | ZCCHC14 | 23174 | 11 | 9 | 20 | |
| GSE54993 | ZCCHC14 | 23174 | 3 | 4 | 63 | |
| GSE54994 | ZCCHC14 | 23174 | 9 | 11 | 33 | |
| GSE60625 | ZCCHC14 | 23174 | 4 | 0 | 7 | |
| GSE74703 | ZCCHC14 | 23174 | 1 | 9 | 26 | |
| GSE74704 | ZCCHC14 | 23174 | 3 | 2 | 15 | |
| TCGA | ZCCHC14 | 23174 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 68; Total Number of normals: 314.
Somatic mutations of ZCCHC14:
Generating mutation plots.
Highly correlated genes for ZCCHC14:
Showing top 20/657 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZCCHC14 | SLC7A6OS | 0.805314 | 3 | 0 | 3 |
| ZCCHC14 | KIAA0513 | 0.745473 | 3 | 0 | 3 |
| ZCCHC14 | RRM2B | 0.730157 | 3 | 0 | 3 |
| ZCCHC14 | SNX18 | 0.714449 | 3 | 0 | 3 |
| ZCCHC14 | MED17 | 0.711976 | 3 | 0 | 3 |
| ZCCHC14 | JMY | 0.707689 | 3 | 0 | 3 |
| ZCCHC14 | TEX10 | 0.704429 | 3 | 0 | 3 |
| ZCCHC14 | NDRG3 | 0.700379 | 3 | 0 | 3 |
| ZCCHC14 | VPS45 | 0.698322 | 3 | 0 | 3 |
| ZCCHC14 | TOR1A | 0.695875 | 3 | 0 | 3 |
| ZCCHC14 | DLD | 0.695213 | 3 | 0 | 3 |
| ZCCHC14 | ARL13B | 0.694675 | 3 | 0 | 3 |
| ZCCHC14 | ELMOD2 | 0.692106 | 3 | 0 | 3 |
| ZCCHC14 | ZZZ3 | 0.685764 | 5 | 0 | 5 |
| ZCCHC14 | MED26 | 0.681189 | 3 | 0 | 3 |
| ZCCHC14 | ACACA | 0.68023 | 4 | 0 | 3 |
| ZCCHC14 | RB1CC1 | 0.675308 | 3 | 0 | 3 |
| ZCCHC14 | ULK1 | 0.674268 | 4 | 0 | 4 |
| ZCCHC14 | SYNC | 0.673957 | 3 | 0 | 3 |
| ZCCHC14 | PAAF1 | 0.673072 | 3 | 0 | 3 |
For details and further investigation, click here
