| Full name: proteasomal ATPase associated factor 1 | Alias Symbol: FLJ11848|Rpn14 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 80227 | HGNC ID: HGNC:25687 | Ensembl Gene: ENSG00000175575 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PAAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAAF1 | 80227 | 218957_s_at | -0.0376 | 0.9740 | |
| GSE20347 | PAAF1 | 80227 | 218957_s_at | 0.1701 | 0.4373 | |
| GSE23400 | PAAF1 | 80227 | 218957_s_at | 0.3436 | 0.0038 | |
| GSE26886 | PAAF1 | 80227 | 218957_s_at | -0.8855 | 0.0146 | |
| GSE29001 | PAAF1 | 80227 | 218957_s_at | -0.0183 | 0.9746 | |
| GSE38129 | PAAF1 | 80227 | 218957_s_at | 0.0046 | 0.9807 | |
| GSE45670 | PAAF1 | 80227 | 218957_s_at | 0.1107 | 0.7604 | |
| GSE53622 | PAAF1 | 80227 | 21966 | -0.0993 | 0.3840 | |
| GSE53624 | PAAF1 | 80227 | 21966 | 0.1014 | 0.2782 | |
| GSE63941 | PAAF1 | 80227 | 218957_s_at | 0.4050 | 0.5734 | |
| GSE77861 | PAAF1 | 80227 | 218957_s_at | -0.1084 | 0.8018 | |
| GSE97050 | PAAF1 | 80227 | A_33_P3374643 | -0.5063 | 0.1553 | |
| SRP007169 | PAAF1 | 80227 | RNAseq | 1.3886 | 0.0229 | |
| SRP064894 | PAAF1 | 80227 | RNAseq | 0.1243 | 0.6061 | |
| SRP133303 | PAAF1 | 80227 | RNAseq | 0.0085 | 0.9732 | |
| SRP159526 | PAAF1 | 80227 | RNAseq | -0.7522 | 0.0431 | |
| SRP193095 | PAAF1 | 80227 | RNAseq | 0.1312 | 0.4688 | |
| SRP219564 | PAAF1 | 80227 | RNAseq | 0.1104 | 0.7955 | |
| TCGA | PAAF1 | 80227 | RNAseq | -0.1126 | 0.2462 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PAAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAAF1 | 80227 | 5 | 9 | 16 | |
| GSE20123 | PAAF1 | 80227 | 5 | 8 | 17 | |
| GSE43470 | PAAF1 | 80227 | 6 | 4 | 33 | |
| GSE46452 | PAAF1 | 80227 | 9 | 20 | 30 | |
| GSE47630 | PAAF1 | 80227 | 6 | 14 | 20 | |
| GSE54993 | PAAF1 | 80227 | 8 | 3 | 59 | |
| GSE54994 | PAAF1 | 80227 | 8 | 15 | 30 | |
| GSE60625 | PAAF1 | 80227 | 0 | 7 | 4 | |
| GSE74703 | PAAF1 | 80227 | 5 | 3 | 28 | |
| GSE74704 | PAAF1 | 80227 | 3 | 4 | 13 | |
| TCGA | PAAF1 | 80227 | 28 | 27 | 41 |
Total number of gains: 83; Total number of losses: 114; Total Number of normals: 291.
Somatic mutations of PAAF1:
Generating mutation plots.
Highly correlated genes for PAAF1:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAAF1 | MRFAP1L1 | 0.754961 | 3 | 0 | 3 |
| PAAF1 | OCIAD1 | 0.751975 | 3 | 0 | 3 |
| PAAF1 | SKA2 | 0.732964 | 3 | 0 | 3 |
| PAAF1 | AK4 | 0.729435 | 3 | 0 | 3 |
| PAAF1 | DCTN4 | 0.726878 | 3 | 0 | 3 |
| PAAF1 | ROCK2 | 0.723655 | 3 | 0 | 3 |
| PAAF1 | CLIP4 | 0.69941 | 4 | 0 | 3 |
| PAAF1 | CYYR1 | 0.697411 | 3 | 0 | 3 |
| PAAF1 | AMOTL1 | 0.69104 | 4 | 0 | 3 |
| PAAF1 | PIK3R1 | 0.689398 | 3 | 0 | 3 |
| PAAF1 | ZNF571 | 0.686435 | 4 | 0 | 4 |
| PAAF1 | PARP8 | 0.685319 | 3 | 0 | 3 |
| PAAF1 | KLHDC1 | 0.68277 | 3 | 0 | 3 |
| PAAF1 | TBC1D20 | 0.678809 | 3 | 0 | 3 |
| PAAF1 | ZCCHC14 | 0.673072 | 3 | 0 | 3 |
| PAAF1 | ENDOD1 | 0.670282 | 4 | 0 | 3 |
| PAAF1 | RND3 | 0.670269 | 4 | 0 | 4 |
| PAAF1 | DNAJC15 | 0.669607 | 3 | 0 | 3 |
| PAAF1 | HIBCH | 0.669573 | 3 | 0 | 3 |
| PAAF1 | SRSF8 | 0.668408 | 5 | 0 | 4 |
For details and further investigation, click here
