| Full name: heme binding protein 2 | Alias Symbol: SOUL | ||
| Type: protein-coding gene | Cytoband: 6q24.1 | ||
| Entrez ID: 23593 | HGNC ID: HGNC:15716 | Ensembl Gene: ENSG00000051620 | OMIM ID: 605825 |
| Drug and gene relationship at DGIdb | |||
Expression of HEBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEBP2 | 23593 | 203430_at | -0.8136 | 0.1697 | |
| GSE20347 | HEBP2 | 23593 | 203430_at | -1.5204 | 0.0000 | |
| GSE23400 | HEBP2 | 23593 | 203430_at | -1.1923 | 0.0000 | |
| GSE26886 | HEBP2 | 23593 | 203430_at | -0.7494 | 0.0014 | |
| GSE29001 | HEBP2 | 23593 | 203430_at | -1.5251 | 0.0000 | |
| GSE38129 | HEBP2 | 23593 | 203430_at | -1.1288 | 0.0000 | |
| GSE45670 | HEBP2 | 23593 | 203430_at | -0.6219 | 0.0079 | |
| GSE53622 | HEBP2 | 23593 | 101151 | -1.1023 | 0.0000 | |
| GSE53624 | HEBP2 | 23593 | 101151 | -1.0906 | 0.0000 | |
| GSE63941 | HEBP2 | 23593 | 203430_at | -0.5910 | 0.2939 | |
| GSE77861 | HEBP2 | 23593 | 203430_at | -1.3011 | 0.0038 | |
| GSE97050 | HEBP2 | 23593 | A_23_P19691 | -0.2919 | 0.3625 | |
| SRP007169 | HEBP2 | 23593 | RNAseq | -3.1949 | 0.0000 | |
| SRP008496 | HEBP2 | 23593 | RNAseq | -2.8666 | 0.0000 | |
| SRP064894 | HEBP2 | 23593 | RNAseq | -1.7086 | 0.0000 | |
| SRP133303 | HEBP2 | 23593 | RNAseq | -1.0904 | 0.0000 | |
| SRP159526 | HEBP2 | 23593 | RNAseq | -1.7144 | 0.0000 | |
| SRP193095 | HEBP2 | 23593 | RNAseq | -1.7831 | 0.0000 | |
| SRP219564 | HEBP2 | 23593 | RNAseq | -1.5759 | 0.0001 | |
| TCGA | HEBP2 | 23593 | RNAseq | -0.0400 | 0.5633 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by HEBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEBP2 | 23593 | 3 | 4 | 23 | |
| GSE20123 | HEBP2 | 23593 | 3 | 3 | 24 | |
| GSE43470 | HEBP2 | 23593 | 5 | 0 | 38 | |
| GSE46452 | HEBP2 | 23593 | 3 | 10 | 46 | |
| GSE47630 | HEBP2 | 23593 | 9 | 4 | 27 | |
| GSE54993 | HEBP2 | 23593 | 3 | 2 | 65 | |
| GSE54994 | HEBP2 | 23593 | 8 | 8 | 37 | |
| GSE60625 | HEBP2 | 23593 | 0 | 1 | 10 | |
| GSE74703 | HEBP2 | 23593 | 4 | 0 | 32 | |
| GSE74704 | HEBP2 | 23593 | 1 | 1 | 18 | |
| TCGA | HEBP2 | 23593 | 11 | 17 | 68 |
Total number of gains: 50; Total number of losses: 50; Total Number of normals: 388.
Somatic mutations of HEBP2:
Generating mutation plots.
Highly correlated genes for HEBP2:
Showing top 20/1711 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEBP2 | CHP1 | 0.815971 | 10 | 0 | 10 |
| HEBP2 | SCNN1B | 0.802652 | 10 | 0 | 10 |
| HEBP2 | BLNK | 0.801666 | 11 | 0 | 11 |
| HEBP2 | RMND5B | 0.799656 | 11 | 0 | 11 |
| HEBP2 | EHD3 | 0.797397 | 11 | 0 | 11 |
| HEBP2 | EPGN | 0.792834 | 3 | 0 | 3 |
| HEBP2 | RAB11A | 0.792064 | 11 | 0 | 11 |
| HEBP2 | GYS2 | 0.791415 | 10 | 0 | 10 |
| HEBP2 | HPGD | 0.790334 | 11 | 0 | 11 |
| HEBP2 | ZFAND2B | 0.789706 | 7 | 0 | 7 |
| HEBP2 | KLB | 0.786792 | 6 | 0 | 6 |
| HEBP2 | NT5C2 | 0.786106 | 11 | 0 | 11 |
| HEBP2 | TMPRSS11E | 0.785691 | 9 | 0 | 9 |
| HEBP2 | SLC37A1 | 0.78415 | 10 | 0 | 10 |
| HEBP2 | PRSS27 | 0.781023 | 6 | 0 | 6 |
| HEBP2 | ABLIM1 | 0.779492 | 11 | 0 | 11 |
| HEBP2 | SMIM5 | 0.777623 | 6 | 0 | 6 |
| HEBP2 | NAGK | 0.777558 | 11 | 0 | 11 |
| HEBP2 | FAM214A | 0.776604 | 7 | 0 | 7 |
| HEBP2 | CRISP3 | 0.77561 | 11 | 0 | 11 |
For details and further investigation, click here
