| Full name: NSF attachment protein alpha | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 8775 | HGNC ID: HGNC:7641 | Ensembl Gene: ENSG00000105402 | OMIM ID: 603215 |
| Drug and gene relationship at DGIdb | |||
Expression of NAPA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAPA | 8775 | 206491_s_at | -0.5135 | 0.1737 | |
| GSE20347 | NAPA | 8775 | 206491_s_at | -1.2739 | 0.0000 | |
| GSE23400 | NAPA | 8775 | 206491_s_at | -0.6823 | 0.0000 | |
| GSE26886 | NAPA | 8775 | 206491_s_at | -1.7066 | 0.0000 | |
| GSE29001 | NAPA | 8775 | 206491_s_at | -0.5751 | 0.0079 | |
| GSE38129 | NAPA | 8775 | 206491_s_at | -0.7971 | 0.0000 | |
| GSE45670 | NAPA | 8775 | 206491_s_at | -0.1922 | 0.3056 | |
| GSE53622 | NAPA | 8775 | 719 | -0.8238 | 0.0000 | |
| GSE53624 | NAPA | 8775 | 719 | -1.0165 | 0.0000 | |
| GSE63941 | NAPA | 8775 | 206491_s_at | 2.0412 | 0.0001 | |
| GSE77861 | NAPA | 8775 | 206491_s_at | -1.0658 | 0.0036 | |
| GSE97050 | NAPA | 8775 | A_23_P55990 | -0.6529 | 0.1140 | |
| SRP007169 | NAPA | 8775 | RNAseq | -1.9035 | 0.0000 | |
| SRP008496 | NAPA | 8775 | RNAseq | -1.8439 | 0.0000 | |
| SRP064894 | NAPA | 8775 | RNAseq | -0.5827 | 0.0137 | |
| SRP133303 | NAPA | 8775 | RNAseq | -0.7530 | 0.0001 | |
| SRP159526 | NAPA | 8775 | RNAseq | -0.7768 | 0.0013 | |
| SRP193095 | NAPA | 8775 | RNAseq | -0.9571 | 0.0000 | |
| SRP219564 | NAPA | 8775 | RNAseq | -0.5916 | 0.0088 | |
| TCGA | NAPA | 8775 | RNAseq | -0.0698 | 0.1249 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by NAPA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAPA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAPA | 8775 | 4 | 4 | 22 | |
| GSE20123 | NAPA | 8775 | 4 | 3 | 23 | |
| GSE43470 | NAPA | 8775 | 3 | 10 | 30 | |
| GSE46452 | NAPA | 8775 | 45 | 1 | 13 | |
| GSE47630 | NAPA | 8775 | 8 | 7 | 25 | |
| GSE54993 | NAPA | 8775 | 17 | 4 | 49 | |
| GSE54994 | NAPA | 8775 | 4 | 14 | 35 | |
| GSE60625 | NAPA | 8775 | 9 | 0 | 2 | |
| GSE74703 | NAPA | 8775 | 3 | 7 | 26 | |
| GSE74704 | NAPA | 8775 | 4 | 1 | 15 | |
| TCGA | NAPA | 8775 | 14 | 18 | 64 |
Total number of gains: 115; Total number of losses: 69; Total Number of normals: 304.
Somatic mutations of NAPA:
Generating mutation plots.
Highly correlated genes for NAPA:
Showing top 20/1621 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAPA | IQCF1 | 0.820729 | 3 | 0 | 3 |
| NAPA | SCNN1B | 0.809022 | 10 | 0 | 10 |
| NAPA | ZFAND2B | 0.790885 | 7 | 0 | 7 |
| NAPA | TRIP10 | 0.79082 | 12 | 0 | 12 |
| NAPA | NAGK | 0.78562 | 11 | 0 | 10 |
| NAPA | SMIM5 | 0.782207 | 7 | 0 | 7 |
| NAPA | SNORA68 | 0.773804 | 4 | 0 | 4 |
| NAPA | CASC3 | 0.773715 | 3 | 0 | 3 |
| NAPA | GDPD3 | 0.773305 | 10 | 0 | 10 |
| NAPA | EVPL | 0.772875 | 11 | 0 | 11 |
| NAPA | RMND5B | 0.771392 | 12 | 0 | 11 |
| NAPA | FCHO2 | 0.769103 | 7 | 0 | 7 |
| NAPA | CA13 | 0.768371 | 3 | 0 | 3 |
| NAPA | LNX1 | 0.766848 | 6 | 0 | 6 |
| NAPA | CRABP2 | 0.765704 | 9 | 0 | 9 |
| NAPA | BARX2 | 0.763758 | 10 | 0 | 10 |
| NAPA | PRSS27 | 0.763646 | 7 | 0 | 7 |
| NAPA | ARHGEF10L | 0.762399 | 11 | 0 | 10 |
| NAPA | RANBP9 | 0.760527 | 11 | 0 | 10 |
| NAPA | CRCT1 | 0.758137 | 10 | 0 | 10 |
For details and further investigation, click here
