| Full name: interleukin 20 | Alias Symbol: ZCYTO10|IL10D|IL-20 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 50604 | HGNC ID: HGNC:6002 | Ensembl Gene: ENSG00000162891 | OMIM ID: 605619 |
| Drug and gene relationship at DGIdb | |||
IL20 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of IL20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL20 | 50604 | 224071_at | 0.4853 | 0.6326 | |
| GSE26886 | IL20 | 50604 | 224071_at | 0.4685 | 0.0349 | |
| GSE45670 | IL20 | 50604 | 224071_at | 0.4518 | 0.1562 | |
| GSE53622 | IL20 | 50604 | 126269 | 0.7056 | 0.0000 | |
| GSE53624 | IL20 | 50604 | 126269 | 1.0191 | 0.0000 | |
| GSE63941 | IL20 | 50604 | 224071_at | -0.1570 | 0.5695 | |
| GSE77861 | IL20 | 50604 | 224071_at | -0.0890 | 0.3921 | |
| GSE97050 | IL20 | 50604 | A_23_P46482 | 0.0514 | 0.8180 | |
| TCGA | IL20 | 50604 | RNAseq | 5.2387 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by IL20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL20 | 50604 | 11 | 0 | 19 | |
| GSE20123 | IL20 | 50604 | 11 | 0 | 19 | |
| GSE43470 | IL20 | 50604 | 7 | 0 | 36 | |
| GSE46452 | IL20 | 50604 | 3 | 1 | 55 | |
| GSE47630 | IL20 | 50604 | 14 | 0 | 26 | |
| GSE54993 | IL20 | 50604 | 0 | 6 | 64 | |
| GSE54994 | IL20 | 50604 | 14 | 0 | 39 | |
| GSE60625 | IL20 | 50604 | 0 | 0 | 11 | |
| GSE74703 | IL20 | 50604 | 7 | 0 | 29 | |
| GSE74704 | IL20 | 50604 | 5 | 0 | 15 | |
| TCGA | IL20 | 50604 | 45 | 3 | 48 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of IL20:
Generating mutation plots.
Highly correlated genes for IL20:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL20 | NID2 | 0.786187 | 3 | 0 | 3 |
| IL20 | RIMS4 | 0.758874 | 3 | 0 | 3 |
| IL20 | SPTA1 | 0.75693 | 4 | 0 | 3 |
| IL20 | CDRT15 | 0.729216 | 3 | 0 | 3 |
| IL20 | BPIFC | 0.716393 | 4 | 0 | 4 |
| IL20 | ZFHX2 | 0.713642 | 3 | 0 | 3 |
| IL20 | AGRP | 0.699467 | 3 | 0 | 3 |
| IL20 | TRH | 0.680492 | 3 | 0 | 3 |
| IL20 | CHD5 | 0.680348 | 3 | 0 | 3 |
| IL20 | OR7A17 | 0.675953 | 3 | 0 | 3 |
| IL20 | SCN1B | 0.666247 | 3 | 0 | 3 |
| IL20 | IL24 | 0.66522 | 6 | 0 | 6 |
| IL20 | NACAD | 0.664566 | 3 | 0 | 3 |
| IL20 | S100A5 | 0.661501 | 4 | 0 | 3 |
| IL20 | ZNF697 | 0.657873 | 4 | 0 | 3 |
| IL20 | NLRP5 | 0.657044 | 4 | 0 | 3 |
| IL20 | MYL7 | 0.651975 | 3 | 0 | 3 |
| IL20 | PPP1R12C | 0.638525 | 3 | 0 | 3 |
| IL20 | CCDC8 | 0.632282 | 3 | 0 | 3 |
| IL20 | RASL11B | 0.627845 | 3 | 0 | 3 |
For details and further investigation, click here
