| Full name: thyroid hormone receptor interactor 4 | Alias Symbol: HsT17391|ZC2HC5|ASC-1 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 9325 | HGNC ID: HGNC:12310 | Ensembl Gene: ENSG00000103671 | OMIM ID: 604501 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIP4 | 9325 | 203732_at | -0.3288 | 0.3888 | |
| GSE20347 | TRIP4 | 9325 | 203732_at | -0.3381 | 0.0172 | |
| GSE23400 | TRIP4 | 9325 | 203732_at | -0.1365 | 0.0573 | |
| GSE26886 | TRIP4 | 9325 | 203732_at | -0.9551 | 0.0001 | |
| GSE29001 | TRIP4 | 9325 | 203732_at | -0.4456 | 0.1179 | |
| GSE38129 | TRIP4 | 9325 | 203732_at | -0.2012 | 0.1075 | |
| GSE45670 | TRIP4 | 9325 | 203732_at | -0.0585 | 0.7328 | |
| GSE53622 | TRIP4 | 9325 | 55472 | -0.2510 | 0.0006 | |
| GSE53624 | TRIP4 | 9325 | 55472 | -0.4160 | 0.0003 | |
| GSE63941 | TRIP4 | 9325 | 203732_at | -0.1695 | 0.6651 | |
| GSE77861 | TRIP4 | 9325 | 203732_at | -0.0793 | 0.7874 | |
| GSE97050 | TRIP4 | 9325 | A_23_P152028 | -0.0781 | 0.8048 | |
| SRP007169 | TRIP4 | 9325 | RNAseq | -1.3074 | 0.0007 | |
| SRP008496 | TRIP4 | 9325 | RNAseq | -1.2327 | 0.0000 | |
| SRP064894 | TRIP4 | 9325 | RNAseq | -0.2727 | 0.0278 | |
| SRP133303 | TRIP4 | 9325 | RNAseq | -0.0488 | 0.7597 | |
| SRP159526 | TRIP4 | 9325 | RNAseq | -0.5265 | 0.1159 | |
| SRP193095 | TRIP4 | 9325 | RNAseq | -0.2341 | 0.0593 | |
| SRP219564 | TRIP4 | 9325 | RNAseq | -0.4000 | 0.0896 | |
| TCGA | TRIP4 | 9325 | RNAseq | 0.0123 | 0.8261 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TRIP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIP4 | 9325 | 7 | 4 | 19 | |
| GSE20123 | TRIP4 | 9325 | 7 | 4 | 19 | |
| GSE43470 | TRIP4 | 9325 | 4 | 6 | 33 | |
| GSE46452 | TRIP4 | 9325 | 3 | 7 | 49 | |
| GSE47630 | TRIP4 | 9325 | 8 | 10 | 22 | |
| GSE54993 | TRIP4 | 9325 | 5 | 6 | 59 | |
| GSE54994 | TRIP4 | 9325 | 6 | 7 | 40 | |
| GSE60625 | TRIP4 | 9325 | 4 | 0 | 7 | |
| GSE74703 | TRIP4 | 9325 | 4 | 3 | 29 | |
| GSE74704 | TRIP4 | 9325 | 3 | 4 | 13 | |
| TCGA | TRIP4 | 9325 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 67; Total Number of normals: 360.
Somatic mutations of TRIP4:
Generating mutation plots.
Highly correlated genes for TRIP4:
Showing top 20/1041 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIP4 | TRIP11 | 0.790559 | 5 | 0 | 5 |
| TRIP4 | ESYT2 | 0.764737 | 3 | 0 | 3 |
| TRIP4 | CTCF | 0.760103 | 3 | 0 | 3 |
| TRIP4 | APPL2 | 0.754059 | 3 | 0 | 3 |
| TRIP4 | C11orf54 | 0.748199 | 3 | 0 | 3 |
| TRIP4 | HDHD2 | 0.742514 | 3 | 0 | 3 |
| TRIP4 | NAPG | 0.740076 | 3 | 0 | 3 |
| TRIP4 | ALKBH3 | 0.739164 | 3 | 0 | 3 |
| TRIP4 | PAIP2 | 0.732627 | 3 | 0 | 3 |
| TRIP4 | ACSL3 | 0.727435 | 5 | 0 | 4 |
| TRIP4 | ARGLU1 | 0.724509 | 3 | 0 | 3 |
| TRIP4 | MXI1 | 0.722452 | 3 | 0 | 3 |
| TRIP4 | FAM83D | 0.720656 | 4 | 0 | 4 |
| TRIP4 | UBE2W | 0.715018 | 3 | 0 | 3 |
| TRIP4 | THAP2 | 0.71389 | 4 | 0 | 3 |
| TRIP4 | KIF21A | 0.712548 | 4 | 0 | 4 |
| TRIP4 | PTGR1 | 0.711899 | 3 | 0 | 3 |
| TRIP4 | GPKOW | 0.711686 | 3 | 0 | 3 |
| TRIP4 | WDR73 | 0.706108 | 3 | 0 | 3 |
| TRIP4 | CCDC66 | 0.705904 | 3 | 0 | 3 |
For details and further investigation, click here
