SNAP29

 

Full name: synaptosome associated protein 29 Alias Symbol: SNAP-29|CEDNIK
Type: protein-coding gene Cytoband: 22q11.21
Entrez ID: 9342 HGNC ID: HGNC:11133 Ensembl Gene: ENSG00000099940 OMIM ID: 604202
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SNAP29:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNAP29 9342 218327_s_at 0.1092 0.7999
GSE20347 SNAP29 9342 218327_s_at -0.6933 0.0008
GSE23400 SNAP29 9342 218327_s_at -0.2398 0.0098
GSE26886 SNAP29 9342 218327_s_at 0.2042 0.5108
GSE29001 SNAP29 9342 218327_s_at -0.6209 0.0327
GSE38129 SNAP29 9342 218327_s_at -0.3759 0.0604
GSE45670 SNAP29 9342 218327_s_at 0.0820 0.8467
GSE53622 SNAP29 9342 70706 -0.1896 0.0257
GSE53624 SNAP29 9342 70706 -0.2125 0.0013
GSE63941 SNAP29 9342 218327_s_at 0.4020 0.5965
GSE77861 SNAP29 9342 218327_s_at -0.3034 0.3698
GSE97050 SNAP29 9342 A_24_P48862 -0.2566 0.3157
SRP007169 SNAP29 9342 RNAseq -0.1105 0.8220
SRP008496 SNAP29 9342 RNAseq -0.0040 0.9910
SRP064894 SNAP29 9342 RNAseq -0.3236 0.0453
SRP133303 SNAP29 9342 RNAseq -0.2381 0.0180
SRP159526 SNAP29 9342 RNAseq -0.4722 0.0503
SRP193095 SNAP29 9342 RNAseq -0.4594 0.0000
SRP219564 SNAP29 9342 RNAseq -0.2490 0.5195
TCGA SNAP29 9342 RNAseq -0.1013 0.0387

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SNAP29 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SNAP29:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNAP29 9342 6 7 17
GSE20123 SNAP29 9342 6 7 17
GSE43470 SNAP29 9342 4 7 32
GSE46452 SNAP29 9342 33 1 25
GSE47630 SNAP29 9342 8 5 27
GSE54993 SNAP29 9342 3 6 61
GSE54994 SNAP29 9342 11 7 35
GSE60625 SNAP29 9342 5 0 6
GSE74703 SNAP29 9342 4 5 27
GSE74704 SNAP29 9342 3 4 13
TCGA SNAP29 9342 27 17 52

Total number of gains: 110; Total number of losses: 66; Total Number of normals: 312.  


 

Somatic mutations of SNAP29:

 

Generating mutation plots.

 

Highly correlated genes for SNAP29:

 

Showing top 20/424 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNAP29EAF10.758598303
SNAP29ITCH0.728575707
SNAP29ZNF5940.726485303
SNAP29IPMK0.721355303
SNAP29CTR90.720855303
SNAP29BCAP290.717833504
SNAP29THUMPD30.713664404
SNAP29C6orf1630.703171303
SNAP29RIOK20.702551403
SNAP29FEM1C0.699448504
SNAP29ZFP36L20.693502303
SNAP29YWHAG0.692758303
SNAP29TRAPPC2L0.68615303
SNAP29ATG2B0.685224303
SNAP29APC0.68473505
SNAP29MTA30.683067303
SNAP29SOS20.682996403
SNAP29UBE2F0.682293303
SNAP29ATF70.68204303
SNAP29SLC25A460.6815504

For details and further investigation, click here