| Full name: ADP ribosylation factor like GTPase 4C | Alias Symbol: LAK | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 10123 | HGNC ID: HGNC:698 | Ensembl Gene: ENSG00000188042 | OMIM ID: 604787 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL4C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL4C | 10123 | 202207_at | -0.4048 | 0.3483 | |
| GSE20347 | ARL4C | 10123 | 202207_at | -0.1337 | 0.6577 | |
| GSE23400 | ARL4C | 10123 | 202207_at | 0.2082 | 0.1225 | |
| GSE26886 | ARL4C | 10123 | 202207_at | -0.2909 | 0.3999 | |
| GSE29001 | ARL4C | 10123 | 202207_at | 0.0222 | 0.9632 | |
| GSE38129 | ARL4C | 10123 | 202207_at | 0.4697 | 0.0739 | |
| GSE45670 | ARL4C | 10123 | 202207_at | -0.4990 | 0.0828 | |
| GSE53622 | ARL4C | 10123 | 78398 | 0.2792 | 0.0280 | |
| GSE53624 | ARL4C | 10123 | 78398 | 0.0239 | 0.7854 | |
| GSE63941 | ARL4C | 10123 | 202207_at | -0.3736 | 0.6447 | |
| GSE77861 | ARL4C | 10123 | 202207_at | 0.0258 | 0.9563 | |
| GSE97050 | ARL4C | 10123 | A_33_P3323722 | 0.4685 | 0.4956 | |
| SRP007169 | ARL4C | 10123 | RNAseq | -0.1273 | 0.7887 | |
| SRP008496 | ARL4C | 10123 | RNAseq | -0.0299 | 0.9052 | |
| SRP064894 | ARL4C | 10123 | RNAseq | 0.4909 | 0.0323 | |
| SRP133303 | ARL4C | 10123 | RNAseq | 0.2005 | 0.4309 | |
| SRP159526 | ARL4C | 10123 | RNAseq | 0.1972 | 0.5379 | |
| SRP193095 | ARL4C | 10123 | RNAseq | -0.5619 | 0.0066 | |
| SRP219564 | ARL4C | 10123 | RNAseq | 0.9848 | 0.0591 | |
| TCGA | ARL4C | 10123 | RNAseq | 0.4986 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARL4C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL4C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL4C | 10123 | 1 | 11 | 18 | |
| GSE20123 | ARL4C | 10123 | 1 | 11 | 18 | |
| GSE43470 | ARL4C | 10123 | 1 | 9 | 33 | |
| GSE46452 | ARL4C | 10123 | 0 | 5 | 54 | |
| GSE47630 | ARL4C | 10123 | 4 | 5 | 31 | |
| GSE54993 | ARL4C | 10123 | 3 | 2 | 65 | |
| GSE54994 | ARL4C | 10123 | 6 | 10 | 37 | |
| GSE60625 | ARL4C | 10123 | 0 | 3 | 8 | |
| GSE74703 | ARL4C | 10123 | 1 | 7 | 28 | |
| GSE74704 | ARL4C | 10123 | 1 | 5 | 14 | |
| TCGA | ARL4C | 10123 | 11 | 28 | 57 |
Total number of gains: 29; Total number of losses: 96; Total Number of normals: 363.
Somatic mutations of ARL4C:
Generating mutation plots.
Highly correlated genes for ARL4C:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL4C | ZFP36L2 | 0.738295 | 3 | 0 | 3 |
| ARL4C | RPS14 | 0.735758 | 4 | 0 | 4 |
| ARL4C | MAT2B | 0.729456 | 3 | 0 | 3 |
| ARL4C | OSBPL10 | 0.719679 | 3 | 0 | 3 |
| ARL4C | MAP1LC3B | 0.711579 | 3 | 0 | 3 |
| ARL4C | RARS2 | 0.708918 | 3 | 0 | 3 |
| ARL4C | RNF145 | 0.705676 | 3 | 0 | 3 |
| ARL4C | MLLT10 | 0.705043 | 3 | 0 | 3 |
| ARL4C | MCFD2 | 0.70401 | 3 | 0 | 3 |
| ARL4C | PPP1R3B | 0.691448 | 4 | 0 | 4 |
| ARL4C | MTPN | 0.687759 | 3 | 0 | 3 |
| ARL4C | IL1RAP | 0.683099 | 3 | 0 | 3 |
| ARL4C | INTU | 0.681303 | 3 | 0 | 3 |
| ARL4C | TERF2IP | 0.681252 | 3 | 0 | 3 |
| ARL4C | RNF183 | 0.675833 | 3 | 0 | 3 |
| ARL4C | PPP2R2A | 0.672366 | 3 | 0 | 3 |
| ARL4C | SDHB | 0.669647 | 3 | 0 | 3 |
| ARL4C | GCNT1 | 0.669192 | 3 | 0 | 3 |
| ARL4C | SLITRK6 | 0.666636 | 4 | 0 | 3 |
| ARL4C | DNAJC1 | 0.665823 | 4 | 0 | 3 |
For details and further investigation, click here
