| Full name: zinc finger FYVE-type containing 28 | Alias Symbol: KIAA1643 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 57732 | HGNC ID: HGNC:29334 | Ensembl Gene: ENSG00000159733 | OMIM ID: 614176 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFYVE28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFYVE28 | 57732 | 232408_at | -0.0549 | 0.9006 | |
| GSE26886 | ZFYVE28 | 57732 | 232408_at | 0.0422 | 0.7735 | |
| GSE45670 | ZFYVE28 | 57732 | 1569369_at | 0.3499 | 0.0291 | |
| GSE53622 | ZFYVE28 | 57732 | 45280 | -1.0666 | 0.0000 | |
| GSE53624 | ZFYVE28 | 57732 | 45280 | -0.8426 | 0.0000 | |
| GSE63941 | ZFYVE28 | 57732 | 232408_at | 0.1906 | 0.3818 | |
| GSE77861 | ZFYVE28 | 57732 | 232408_at | -0.0472 | 0.7843 | |
| GSE97050 | ZFYVE28 | 57732 | A_32_P104746 | -0.0436 | 0.9134 | |
| SRP064894 | ZFYVE28 | 57732 | RNAseq | -0.4255 | 0.0833 | |
| SRP133303 | ZFYVE28 | 57732 | RNAseq | -0.5255 | 0.1465 | |
| SRP159526 | ZFYVE28 | 57732 | RNAseq | -0.6477 | 0.1074 | |
| SRP193095 | ZFYVE28 | 57732 | RNAseq | -0.3848 | 0.1025 | |
| SRP219564 | ZFYVE28 | 57732 | RNAseq | 0.1462 | 0.8037 | |
| TCGA | ZFYVE28 | 57732 | RNAseq | -0.7149 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZFYVE28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFYVE28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFYVE28 | 57732 | 0 | 16 | 14 | |
| GSE20123 | ZFYVE28 | 57732 | 0 | 16 | 14 | |
| GSE43470 | ZFYVE28 | 57732 | 0 | 17 | 26 | |
| GSE46452 | ZFYVE28 | 57732 | 1 | 36 | 22 | |
| GSE47630 | ZFYVE28 | 57732 | 1 | 19 | 20 | |
| GSE54993 | ZFYVE28 | 57732 | 11 | 0 | 59 | |
| GSE54994 | ZFYVE28 | 57732 | 3 | 12 | 38 | |
| GSE60625 | ZFYVE28 | 57732 | 0 | 0 | 11 | |
| GSE74703 | ZFYVE28 | 57732 | 0 | 13 | 23 | |
| GSE74704 | ZFYVE28 | 57732 | 0 | 8 | 12 | |
| TCGA | ZFYVE28 | 57732 | 9 | 47 | 40 |
Total number of gains: 25; Total number of losses: 184; Total Number of normals: 279.
Somatic mutations of ZFYVE28:
Generating mutation plots.
Highly correlated genes for ZFYVE28:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFYVE28 | CPEB3 | 0.720933 | 3 | 0 | 3 |
| ZFYVE28 | SLC35A4 | 0.701316 | 3 | 0 | 3 |
| ZFYVE28 | MAPT-AS1 | 0.679679 | 3 | 0 | 3 |
| ZFYVE28 | RTP3 | 0.6635 | 3 | 0 | 3 |
| ZFYVE28 | BOK | 0.648694 | 3 | 0 | 3 |
| ZFYVE28 | DEF6 | 0.636587 | 4 | 0 | 4 |
| ZFYVE28 | SMIM14 | 0.625436 | 3 | 0 | 3 |
| ZFYVE28 | ATP10B | 0.617521 | 3 | 0 | 3 |
| ZFYVE28 | ATP6AP1 | 0.614896 | 4 | 0 | 3 |
| ZFYVE28 | KCNK16 | 0.614679 | 3 | 0 | 3 |
| ZFYVE28 | STIM1 | 0.612302 | 3 | 0 | 3 |
| ZFYVE28 | CLINT1 | 0.60445 | 3 | 0 | 3 |
| ZFYVE28 | MSRA | 0.597254 | 3 | 0 | 3 |
| ZFYVE28 | NPBWR2 | 0.592828 | 3 | 0 | 3 |
| ZFYVE28 | TMEM200C | 0.591365 | 3 | 0 | 3 |
| ZFYVE28 | RBM47 | 0.589167 | 3 | 0 | 3 |
| ZFYVE28 | ZZEF1 | 0.587489 | 3 | 0 | 3 |
| ZFYVE28 | LDHD | 0.587133 | 3 | 0 | 3 |
| ZFYVE28 | BATF | 0.583744 | 3 | 0 | 3 |
| ZFYVE28 | FCER1A | 0.582587 | 4 | 0 | 3 |
For details and further investigation, click here
