| Full name: methionine sulfoxide reductase A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 4482 | HGNC ID: HGNC:7377 | Ensembl Gene: ENSG00000175806 | OMIM ID: 601250 |
Expression of MSRA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSRA | 4482 | 219281_at | -0.7388 | 0.0340 | |
| GSE20347 | MSRA | 4482 | 219281_at | -1.0786 | 0.0000 | |
| GSE23400 | MSRA | 4482 | 219281_at | -0.5997 | 0.0000 | |
| GSE26886 | MSRA | 4482 | 219281_at | -0.7705 | 0.0016 | |
| GSE29001 | MSRA | 4482 | 219281_at | -1.2833 | 0.0000 | |
| GSE38129 | MSRA | 4482 | 219281_at | -1.0446 | 0.0000 | |
| GSE45670 | MSRA | 4482 | 219281_at | -0.6908 | 0.0006 | |
| GSE53622 | MSRA | 4482 | 46335 | -1.4289 | 0.0000 | |
| GSE53624 | MSRA | 4482 | 46335 | -1.4467 | 0.0000 | |
| GSE63941 | MSRA | 4482 | 219281_at | -1.6818 | 0.0194 | |
| GSE77861 | MSRA | 4482 | 219281_at | -0.9876 | 0.0078 | |
| GSE97050 | MSRA | 4482 | A_23_P61426 | -0.6259 | 0.1313 | |
| SRP007169 | MSRA | 4482 | RNAseq | -2.2685 | 0.0001 | |
| SRP064894 | MSRA | 4482 | RNAseq | -0.4698 | 0.1598 | |
| SRP133303 | MSRA | 4482 | RNAseq | -1.2209 | 0.0000 | |
| SRP159526 | MSRA | 4482 | RNAseq | -0.7330 | 0.0196 | |
| SRP193095 | MSRA | 4482 | RNAseq | -1.1469 | 0.0000 | |
| SRP219564 | MSRA | 4482 | RNAseq | -0.7549 | 0.1508 | |
| TCGA | MSRA | 4482 | RNAseq | -0.6286 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by MSRA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MSRA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MSRA | 4482 | 4 | 11 | 15 | |
| GSE20123 | MSRA | 4482 | 4 | 11 | 15 | |
| GSE43470 | MSRA | 4482 | 4 | 9 | 30 | |
| GSE46452 | MSRA | 4482 | 12 | 14 | 33 | |
| GSE47630 | MSRA | 4482 | 10 | 7 | 23 | |
| GSE54993 | MSRA | 4482 | 3 | 14 | 53 | |
| GSE54994 | MSRA | 4482 | 9 | 19 | 25 | |
| GSE60625 | MSRA | 4482 | 3 | 0 | 8 | |
| GSE74703 | MSRA | 4482 | 4 | 7 | 25 | |
| GSE74704 | MSRA | 4482 | 3 | 7 | 10 | |
| TCGA | MSRA | 4482 | 13 | 40 | 43 |
Total number of gains: 69; Total number of losses: 139; Total Number of normals: 280.
Somatic mutations of MSRA:
Generating mutation plots.
Highly correlated genes for MSRA:
Showing top 20/1816 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSRA | CLEC3B | 0.830183 | 3 | 0 | 3 |
| MSRA | CYP21A2 | 0.785606 | 3 | 0 | 3 |
| MSRA | FBXO8 | 0.782309 | 6 | 0 | 6 |
| MSRA | GPD1L | 0.779256 | 11 | 0 | 11 |
| MSRA | SNORA68 | 0.77836 | 4 | 0 | 4 |
| MSRA | CGNL1 | 0.775083 | 7 | 0 | 7 |
| MSRA | KIAA0232 | 0.771643 | 10 | 0 | 10 |
| MSRA | GPRASP2 | 0.768493 | 3 | 0 | 3 |
| MSRA | ATF7 | 0.76735 | 4 | 0 | 4 |
| MSRA | RBPJL | 0.767189 | 3 | 0 | 3 |
| MSRA | ACOX3 | 0.76684 | 10 | 0 | 10 |
| MSRA | SORBS2 | 0.762829 | 11 | 0 | 11 |
| MSRA | CRYL1 | 0.762322 | 11 | 0 | 10 |
| MSRA | CCL14 | 0.761304 | 3 | 0 | 3 |
| MSRA | UBL3 | 0.756694 | 10 | 0 | 10 |
| MSRA | CAB39L | 0.755398 | 11 | 0 | 11 |
| MSRA | SORCS1 | 0.753842 | 4 | 0 | 4 |
| MSRA | CALCOCO2 | 0.753643 | 11 | 0 | 11 |
| MSRA | EIF4E3 | 0.751779 | 8 | 0 | 7 |
| MSRA | SMDT1 | 0.750576 | 4 | 0 | 4 |
For details and further investigation, click here
