| Full name: zinc finger protein 117 | Alias Symbol: HPF9|H-plk | ||
| Type: protein-coding gene | Cytoband: 7q11.21 | ||
| Entrez ID: 51351 | HGNC ID: HGNC:12897 | Ensembl Gene: ENSG00000152926 | OMIM ID: 194624 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF117:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF117 | 51351 | 235408_x_at | 0.9616 | 0.4042 | |
| GSE20347 | ZNF117 | 51351 | 207605_x_at | 0.1950 | 0.6057 | |
| GSE23400 | ZNF117 | 51351 | 207605_x_at | 0.0328 | 0.7782 | |
| GSE26886 | ZNF117 | 51351 | 235408_x_at | -1.1440 | 0.0177 | |
| GSE29001 | ZNF117 | 51351 | 207605_x_at | -0.2885 | 0.6974 | |
| GSE38129 | ZNF117 | 51351 | 207605_x_at | 0.2989 | 0.3453 | |
| GSE45670 | ZNF117 | 51351 | 235408_x_at | 0.3141 | 0.4461 | |
| GSE53622 | ZNF117 | 51351 | 29038 | -0.6721 | 0.0000 | |
| GSE53624 | ZNF117 | 51351 | 29038 | -0.8460 | 0.0000 | |
| GSE63941 | ZNF117 | 51351 | 207605_x_at | -0.0886 | 0.9377 | |
| GSE77861 | ZNF117 | 51351 | 207605_x_at | -0.6637 | 0.2611 | |
| GSE97050 | ZNF117 | 51351 | A_33_P3222744 | 0.0335 | 0.9243 | |
| SRP007169 | ZNF117 | 51351 | RNAseq | 0.3975 | 0.6670 | |
| SRP008496 | ZNF117 | 51351 | RNAseq | 2.7414 | 0.0030 | |
| SRP064894 | ZNF117 | 51351 | RNAseq | 0.3546 | 0.4265 | |
| SRP133303 | ZNF117 | 51351 | RNAseq | -0.2456 | 0.3349 | |
| SRP159526 | ZNF117 | 51351 | RNAseq | -0.4170 | 0.4245 | |
| SRP193095 | ZNF117 | 51351 | RNAseq | -0.2330 | 0.3244 | |
| SRP219564 | ZNF117 | 51351 | RNAseq | -0.1713 | 0.6641 | |
| TCGA | ZNF117 | 51351 | RNAseq | 0.1308 | 0.3258 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ZNF117 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF117:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF117 | 51351 | 11 | 2 | 17 | |
| GSE20123 | ZNF117 | 51351 | 10 | 2 | 18 | |
| GSE43470 | ZNF117 | 51351 | 2 | 1 | 40 | |
| GSE46452 | ZNF117 | 51351 | 13 | 0 | 46 | |
| GSE47630 | ZNF117 | 51351 | 7 | 1 | 32 | |
| GSE54993 | ZNF117 | 51351 | 2 | 7 | 61 | |
| GSE54994 | ZNF117 | 51351 | 12 | 4 | 37 | |
| GSE60625 | ZNF117 | 51351 | 0 | 0 | 11 | |
| GSE74703 | ZNF117 | 51351 | 2 | 1 | 33 | |
| GSE74704 | ZNF117 | 51351 | 5 | 1 | 14 | |
| TCGA | ZNF117 | 51351 | 46 | 5 | 45 |
Total number of gains: 110; Total number of losses: 24; Total Number of normals: 354.
Somatic mutations of ZNF117:
Generating mutation plots.
Highly correlated genes for ZNF117:
Showing top 20/324 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF117 | MARS2 | 0.725896 | 3 | 0 | 3 |
| ZNF117 | XRN1 | 0.713244 | 3 | 0 | 3 |
| ZNF117 | FASTKD3 | 0.69411 | 3 | 0 | 3 |
| ZNF117 | ZNF439 | 0.685901 | 3 | 0 | 3 |
| ZNF117 | CCDC85C | 0.679576 | 3 | 0 | 3 |
| ZNF117 | FBXO27 | 0.676771 | 4 | 0 | 3 |
| ZNF117 | NUDT19 | 0.66536 | 3 | 0 | 3 |
| ZNF117 | TMCO6 | 0.66182 | 4 | 0 | 3 |
| ZNF117 | SMURF1 | 0.660356 | 3 | 0 | 3 |
| ZNF117 | ZNF165 | 0.66012 | 3 | 0 | 3 |
| ZNF117 | GPBP1 | 0.655809 | 4 | 0 | 4 |
| ZNF117 | EPM2AIP1 | 0.653011 | 4 | 0 | 4 |
| ZNF117 | MTPAP | 0.652762 | 3 | 0 | 3 |
| ZNF117 | SOS2 | 0.647464 | 3 | 0 | 3 |
| ZNF117 | SPIN4 | 0.644207 | 5 | 0 | 4 |
| ZNF117 | LMTK2 | 0.64288 | 3 | 0 | 3 |
| ZNF117 | CPEB4 | 0.638297 | 5 | 0 | 4 |
| ZNF117 | FBXO10 | 0.638246 | 4 | 0 | 3 |
| ZNF117 | RXRA | 0.636099 | 4 | 0 | 3 |
| ZNF117 | SCYL3 | 0.633504 | 5 | 0 | 4 |
For details and further investigation, click here
