| Full name: F-box protein 27 | Alias Symbol: Fbg5|Fbx27 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 126433 | HGNC ID: HGNC:18753 | Ensembl Gene: | OMIM ID: 609099 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO27 | 126433 | 235169_at | 0.1342 | 0.6837 | |
| GSE26886 | FBXO27 | 126433 | 235169_at | 0.1076 | 0.5333 | |
| GSE45670 | FBXO27 | 126433 | 235169_at | 0.1154 | 0.3902 | |
| GSE53622 | FBXO27 | 126433 | 93584 | -0.1102 | 0.6151 | |
| GSE53624 | FBXO27 | 126433 | 93584 | 0.1053 | 0.5058 | |
| GSE63941 | FBXO27 | 126433 | 235169_at | 0.8273 | 0.0591 | |
| GSE77861 | FBXO27 | 126433 | 235169_at | 0.1599 | 0.4068 | |
| GSE97050 | FBXO27 | 126433 | A_24_P113264 | -0.1704 | 0.5979 | |
| SRP007169 | FBXO27 | 126433 | RNAseq | 0.7860 | 0.3073 | |
| SRP064894 | FBXO27 | 126433 | RNAseq | 0.0024 | 0.9929 | |
| SRP133303 | FBXO27 | 126433 | RNAseq | -0.0809 | 0.6375 | |
| SRP159526 | FBXO27 | 126433 | RNAseq | -0.0300 | 0.9429 | |
| SRP193095 | FBXO27 | 126433 | RNAseq | -0.2700 | 0.1805 | |
| SRP219564 | FBXO27 | 126433 | RNAseq | -0.2789 | 0.5230 | |
| TCGA | FBXO27 | 126433 | RNAseq | 0.4071 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO27 | 126433 | 7 | 4 | 19 | |
| GSE20123 | FBXO27 | 126433 | 7 | 3 | 20 | |
| GSE43470 | FBXO27 | 126433 | 4 | 10 | 29 | |
| GSE46452 | FBXO27 | 126433 | 47 | 2 | 10 | |
| GSE47630 | FBXO27 | 126433 | 9 | 5 | 26 | |
| GSE54993 | FBXO27 | 126433 | 17 | 3 | 50 | |
| GSE54994 | FBXO27 | 126433 | 6 | 9 | 38 | |
| GSE60625 | FBXO27 | 126433 | 9 | 0 | 2 | |
| GSE74703 | FBXO27 | 126433 | 4 | 6 | 26 | |
| GSE74704 | FBXO27 | 126433 | 7 | 1 | 12 | |
| TCGA | FBXO27 | 126433 | 14 | 16 | 66 |
Total number of gains: 131; Total number of losses: 59; Total Number of normals: 298.
Somatic mutations of FBXO27:
Generating mutation plots.
Highly correlated genes for FBXO27:
Showing top 20/173 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO27 | HHAT | 0.795261 | 3 | 0 | 3 |
| FBXO27 | GATAD2B | 0.703852 | 4 | 0 | 4 |
| FBXO27 | RAB25 | 0.684573 | 3 | 0 | 3 |
| FBXO27 | ZNF117 | 0.676771 | 4 | 0 | 3 |
| FBXO27 | SLC10A3 | 0.667811 | 4 | 0 | 4 |
| FBXO27 | CHD3 | 0.663552 | 3 | 0 | 3 |
| FBXO27 | IL17C | 0.659944 | 3 | 0 | 3 |
| FBXO27 | PLD2 | 0.645802 | 3 | 0 | 3 |
| FBXO27 | EIF3H | 0.638926 | 3 | 0 | 3 |
| FBXO27 | MDFI | 0.638122 | 3 | 0 | 3 |
| FBXO27 | PPAT | 0.635861 | 3 | 0 | 3 |
| FBXO27 | TMEM63C | 0.633453 | 3 | 0 | 3 |
| FBXO27 | RIMS2 | 0.630826 | 4 | 0 | 3 |
| FBXO27 | BCL11A | 0.629731 | 3 | 0 | 3 |
| FBXO27 | KCTD13 | 0.628992 | 4 | 0 | 3 |
| FBXO27 | PTER | 0.628991 | 3 | 0 | 3 |
| FBXO27 | E2F3 | 0.627441 | 3 | 0 | 3 |
| FBXO27 | UBQLN4 | 0.625172 | 3 | 0 | 3 |
| FBXO27 | CHD7 | 0.625103 | 4 | 0 | 3 |
| FBXO27 | CDK5R1 | 0.625016 | 3 | 0 | 3 |
For details and further investigation, click here
