| Full name: F-box protein 10 | Alias Symbol: FBX10 | ||
| Type: protein-coding gene | Cytoband: 9p13.2 | ||
| Entrez ID: 26267 | HGNC ID: HGNC:13589 | Ensembl Gene: ENSG00000147912 | OMIM ID: 609092 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO10 | 26267 | 227222_at | -0.0689 | 0.8667 | |
| GSE26886 | FBXO10 | 26267 | 227222_at | -0.4309 | 0.0018 | |
| GSE45670 | FBXO10 | 26267 | 227222_at | 0.1640 | 0.2502 | |
| GSE53622 | FBXO10 | 26267 | 12461 | -0.9286 | 0.0000 | |
| GSE53624 | FBXO10 | 26267 | 12461 | -0.6216 | 0.0000 | |
| GSE63941 | FBXO10 | 26267 | 227222_at | -0.3763 | 0.1369 | |
| GSE77861 | FBXO10 | 26267 | 227222_at | -0.4596 | 0.0019 | |
| GSE97050 | FBXO10 | 26267 | A_33_P3259507 | -0.2436 | 0.2987 | |
| SRP007169 | FBXO10 | 26267 | RNAseq | -1.4757 | 0.0137 | |
| SRP008496 | FBXO10 | 26267 | RNAseq | -0.4213 | 0.3919 | |
| SRP064894 | FBXO10 | 26267 | RNAseq | -0.0968 | 0.5755 | |
| SRP133303 | FBXO10 | 26267 | RNAseq | -0.5088 | 0.0224 | |
| SRP159526 | FBXO10 | 26267 | RNAseq | -0.7494 | 0.0025 | |
| SRP193095 | FBXO10 | 26267 | RNAseq | -0.4556 | 0.0081 | |
| SRP219564 | FBXO10 | 26267 | RNAseq | -0.2783 | 0.3756 | |
| TCGA | FBXO10 | 26267 | RNAseq | -0.2430 | 0.0085 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FBXO10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO10 | 26267 | 4 | 13 | 13 | |
| GSE20123 | FBXO10 | 26267 | 4 | 13 | 13 | |
| GSE43470 | FBXO10 | 26267 | 1 | 12 | 30 | |
| GSE46452 | FBXO10 | 26267 | 6 | 15 | 38 | |
| GSE47630 | FBXO10 | 26267 | 1 | 20 | 19 | |
| GSE54993 | FBXO10 | 26267 | 6 | 0 | 64 | |
| GSE54994 | FBXO10 | 26267 | 5 | 13 | 35 | |
| GSE60625 | FBXO10 | 26267 | 0 | 0 | 11 | |
| GSE74703 | FBXO10 | 26267 | 1 | 8 | 27 | |
| GSE74704 | FBXO10 | 26267 | 1 | 9 | 10 | |
| TCGA | FBXO10 | 26267 | 14 | 44 | 38 |
Total number of gains: 43; Total number of losses: 147; Total Number of normals: 298.
Somatic mutations of FBXO10:
Generating mutation plots.
Highly correlated genes for FBXO10:
Showing top 20/786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO10 | GNG5 | 0.82079 | 3 | 0 | 3 |
| FBXO10 | NPRL2 | 0.805568 | 3 | 0 | 3 |
| FBXO10 | ALKBH7 | 0.793508 | 3 | 0 | 3 |
| FBXO10 | SCFD2 | 0.792766 | 3 | 0 | 3 |
| FBXO10 | NDST2 | 0.787942 | 3 | 0 | 3 |
| FBXO10 | UQCRQ | 0.776007 | 3 | 0 | 3 |
| FBXO10 | ID4 | 0.772654 | 3 | 0 | 3 |
| FBXO10 | ZNF35 | 0.764979 | 3 | 0 | 3 |
| FBXO10 | ARL6IP5 | 0.759343 | 4 | 0 | 4 |
| FBXO10 | RAB5B | 0.752372 | 4 | 0 | 4 |
| FBXO10 | CD59 | 0.750363 | 3 | 0 | 3 |
| FBXO10 | BRK1 | 0.746544 | 4 | 0 | 4 |
| FBXO10 | UBE4B | 0.745391 | 3 | 0 | 3 |
| FBXO10 | HOXA2 | 0.74493 | 3 | 0 | 3 |
| FBXO10 | MRPS36 | 0.743487 | 3 | 0 | 3 |
| FBXO10 | MBLAC2 | 0.743461 | 3 | 0 | 3 |
| FBXO10 | RNLS | 0.743239 | 3 | 0 | 3 |
| FBXO10 | POLH | 0.736645 | 3 | 0 | 3 |
| FBXO10 | PRKAR2A | 0.736491 | 4 | 0 | 4 |
| FBXO10 | ANGPTL6 | 0.735965 | 3 | 0 | 3 |
For details and further investigation, click here
