| Full name: CGG triplet repeat binding protein 1 | Alias Symbol: p20-CGGBP|CGGBP | ||
| Type: protein-coding gene | Cytoband: 3p11.1 | ||
| Entrez ID: 8545 | HGNC ID: HGNC:1888 | Ensembl Gene: ENSG00000163320 | OMIM ID: 603363 |
| Drug and gene relationship at DGIdb | |||
Expression of CGGBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CGGBP1 | 8545 | 224599_at | -0.4595 | 0.0808 | |
| GSE20347 | CGGBP1 | 8545 | 206861_s_at | -0.2663 | 0.1027 | |
| GSE23400 | CGGBP1 | 8545 | 206861_s_at | -0.0376 | 0.6165 | |
| GSE26886 | CGGBP1 | 8545 | 224599_at | -1.0619 | 0.0001 | |
| GSE29001 | CGGBP1 | 8545 | 206861_s_at | -0.2388 | 0.4329 | |
| GSE38129 | CGGBP1 | 8545 | 206861_s_at | -0.2611 | 0.0654 | |
| GSE45670 | CGGBP1 | 8545 | 224599_at | -0.3425 | 0.0225 | |
| GSE53622 | CGGBP1 | 8545 | 151326 | -0.4478 | 0.0000 | |
| GSE53624 | CGGBP1 | 8545 | 151326 | -0.6126 | 0.0000 | |
| GSE63941 | CGGBP1 | 8545 | 224599_at | -1.0139 | 0.0289 | |
| GSE77861 | CGGBP1 | 8545 | 224599_at | -0.3697 | 0.0209 | |
| GSE97050 | CGGBP1 | 8545 | A_23_P363163 | -0.5072 | 0.1042 | |
| SRP007169 | CGGBP1 | 8545 | RNAseq | -1.1476 | 0.0014 | |
| SRP008496 | CGGBP1 | 8545 | RNAseq | -0.9072 | 0.0000 | |
| SRP064894 | CGGBP1 | 8545 | RNAseq | -0.1848 | 0.2723 | |
| SRP133303 | CGGBP1 | 8545 | RNAseq | 0.3793 | 0.2206 | |
| SRP159526 | CGGBP1 | 8545 | RNAseq | -0.1127 | 0.7609 | |
| SRP193095 | CGGBP1 | 8545 | RNAseq | -0.5986 | 0.0000 | |
| SRP219564 | CGGBP1 | 8545 | RNAseq | -0.5720 | 0.0485 | |
| TCGA | CGGBP1 | 8545 | RNAseq | -0.1575 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CGGBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CGGBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CGGBP1 | 8545 | 3 | 15 | 12 | |
| GSE20123 | CGGBP1 | 8545 | 3 | 16 | 11 | |
| GSE43470 | CGGBP1 | 8545 | 4 | 19 | 20 | |
| GSE46452 | CGGBP1 | 8545 | 3 | 16 | 40 | |
| GSE47630 | CGGBP1 | 8545 | 4 | 18 | 18 | |
| GSE54993 | CGGBP1 | 8545 | 4 | 3 | 63 | |
| GSE54994 | CGGBP1 | 8545 | 3 | 27 | 23 | |
| GSE60625 | CGGBP1 | 8545 | 0 | 6 | 5 | |
| GSE74703 | CGGBP1 | 8545 | 4 | 17 | 15 | |
| GSE74704 | CGGBP1 | 8545 | 2 | 11 | 7 | |
| TCGA | CGGBP1 | 8545 | 3 | 70 | 23 |
Total number of gains: 33; Total number of losses: 218; Total Number of normals: 237.
Somatic mutations of CGGBP1:
Generating mutation plots.
Highly correlated genes for CGGBP1:
Showing top 20/1224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CGGBP1 | APOB | 0.779498 | 3 | 0 | 3 |
| CGGBP1 | PITHD1 | 0.772914 | 4 | 0 | 4 |
| CGGBP1 | CCNYL1 | 0.757833 | 3 | 0 | 3 |
| CGGBP1 | HDHD2 | 0.753373 | 5 | 0 | 4 |
| CGGBP1 | MOB3B | 0.751767 | 3 | 0 | 3 |
| CGGBP1 | HOXA4 | 0.743676 | 4 | 0 | 3 |
| CGGBP1 | XPC | 0.743424 | 4 | 0 | 4 |
| CGGBP1 | CD59 | 0.735017 | 5 | 0 | 4 |
| CGGBP1 | SPAG17 | 0.730612 | 3 | 0 | 3 |
| CGGBP1 | AMOTL1 | 0.72848 | 4 | 0 | 3 |
| CGGBP1 | KDM5D | 0.727092 | 3 | 0 | 3 |
| CGGBP1 | TRERF1 | 0.722252 | 4 | 0 | 3 |
| CGGBP1 | SLC12A6 | 0.71975 | 4 | 0 | 3 |
| CGGBP1 | ZNF416 | 0.718472 | 4 | 0 | 3 |
| CGGBP1 | PPP2R5C | 0.715772 | 3 | 0 | 3 |
| CGGBP1 | GNG5 | 0.715358 | 3 | 0 | 3 |
| CGGBP1 | PPID | 0.713407 | 3 | 0 | 3 |
| CGGBP1 | ZNF436 | 0.712982 | 4 | 0 | 4 |
| CGGBP1 | SNX17 | 0.712714 | 3 | 0 | 3 |
| CGGBP1 | ZHX1 | 0.710651 | 5 | 0 | 4 |
For details and further investigation, click here
