| Full name: chromosome 4 open reading frame 3 | Alias Symbol: HCVFTP1|ALN | ||
| Type: protein-coding gene | Cytoband: 4q26 | ||
| Entrez ID: 401152 | HGNC ID: HGNC:19225 | Ensembl Gene: ENSG00000164096 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C4orf3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C4orf3 | 401152 | 224602_at | -1.2406 | 0.0947 | |
| GSE26886 | C4orf3 | 401152 | 224604_at | -1.0456 | 0.0002 | |
| GSE45670 | C4orf3 | 401152 | 224602_at | -0.9233 | 0.0028 | |
| GSE53622 | C4orf3 | 401152 | 93569 | -1.3251 | 0.0000 | |
| GSE53624 | C4orf3 | 401152 | 93569 | -1.6682 | 0.0000 | |
| GSE63941 | C4orf3 | 401152 | 224602_at | -0.7285 | 0.2604 | |
| GSE77861 | C4orf3 | 401152 | 224602_at | -1.7349 | 0.0060 | |
| GSE97050 | C4orf3 | 401152 | A_33_P3285824 | -0.7662 | 0.2151 | |
| SRP007169 | C4orf3 | 401152 | RNAseq | -3.0731 | 0.0000 | |
| SRP008496 | C4orf3 | 401152 | RNAseq | -2.7670 | 0.0000 | |
| SRP064894 | C4orf3 | 401152 | RNAseq | -1.9348 | 0.0000 | |
| SRP133303 | C4orf3 | 401152 | RNAseq | -1.4993 | 0.0000 | |
| SRP159526 | C4orf3 | 401152 | RNAseq | -1.7988 | 0.0000 | |
| SRP193095 | C4orf3 | 401152 | RNAseq | -2.3168 | 0.0000 | |
| SRP219564 | C4orf3 | 401152 | RNAseq | -2.1392 | 0.0001 | |
| TCGA | C4orf3 | 401152 | RNAseq | -0.0770 | 0.2250 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by C4orf3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C4orf3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C4orf3 | 401152 | 1 | 13 | 16 | |
| GSE20123 | C4orf3 | 401152 | 1 | 13 | 16 | |
| GSE43470 | C4orf3 | 401152 | 0 | 13 | 30 | |
| GSE46452 | C4orf3 | 401152 | 1 | 36 | 22 | |
| GSE47630 | C4orf3 | 401152 | 0 | 22 | 18 | |
| GSE54993 | C4orf3 | 401152 | 9 | 0 | 61 | |
| GSE54994 | C4orf3 | 401152 | 1 | 10 | 42 | |
| GSE60625 | C4orf3 | 401152 | 0 | 1 | 10 | |
| GSE74703 | C4orf3 | 401152 | 0 | 11 | 25 | |
| GSE74704 | C4orf3 | 401152 | 0 | 7 | 13 | |
| TCGA | C4orf3 | 401152 | 9 | 34 | 53 |
Total number of gains: 22; Total number of losses: 160; Total Number of normals: 306.
Somatic mutations of C4orf3:
Generating mutation plots.
Highly correlated genes for C4orf3:
Showing top 20/1505 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C4orf3 | SASH1 | 0.819901 | 7 | 0 | 7 |
| C4orf3 | KRT78 | 0.818307 | 7 | 0 | 7 |
| C4orf3 | CA13 | 0.814628 | 3 | 0 | 3 |
| C4orf3 | PRSS2 | 0.809496 | 4 | 0 | 4 |
| C4orf3 | GYS2 | 0.8088 | 6 | 0 | 6 |
| C4orf3 | PSCA | 0.806281 | 4 | 0 | 4 |
| C4orf3 | RANBP9 | 0.805283 | 7 | 0 | 7 |
| C4orf3 | ANXA9 | 0.802183 | 7 | 0 | 7 |
| C4orf3 | CCNG2 | 0.800548 | 8 | 0 | 8 |
| C4orf3 | C18orf25 | 0.800333 | 7 | 0 | 7 |
| C4orf3 | USP6NL | 0.79963 | 7 | 0 | 7 |
| C4orf3 | CLIC3 | 0.797615 | 5 | 0 | 5 |
| C4orf3 | BLNK | 0.797604 | 7 | 0 | 7 |
| C4orf3 | SPNS2 | 0.797564 | 5 | 0 | 5 |
| C4orf3 | ATP6V1C2 | 0.79576 | 4 | 0 | 4 |
| C4orf3 | SLC16A6 | 0.794677 | 7 | 0 | 7 |
| C4orf3 | NUCB2 | 0.794474 | 7 | 0 | 7 |
| C4orf3 | CPPED1 | 0.793553 | 7 | 0 | 7 |
| C4orf3 | NAGK | 0.792463 | 7 | 0 | 7 |
| C4orf3 | ENDOU | 0.786805 | 7 | 0 | 7 |
For details and further investigation, click here
