| Full name: lipin 2 | Alias Symbol: KIAA0249 | ||
| Type: protein-coding gene | Cytoband: 18p11.31 | ||
| Entrez ID: 9663 | HGNC ID: HGNC:14450 | Ensembl Gene: ENSG00000101577 | OMIM ID: 605519 |
| Drug and gene relationship at DGIdb | |||
Expression of LPIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPIN2 | 9663 | 202460_s_at | -0.1980 | 0.7571 | |
| GSE20347 | LPIN2 | 9663 | 202460_s_at | -0.5011 | 0.0546 | |
| GSE23400 | LPIN2 | 9663 | 202459_s_at | -0.5898 | 0.0000 | |
| GSE26886 | LPIN2 | 9663 | 202460_s_at | -1.7488 | 0.0000 | |
| GSE29001 | LPIN2 | 9663 | 202460_s_at | -0.8728 | 0.0492 | |
| GSE38129 | LPIN2 | 9663 | 202460_s_at | -0.6009 | 0.0011 | |
| GSE45670 | LPIN2 | 9663 | 202460_s_at | -0.4880 | 0.1613 | |
| GSE53622 | LPIN2 | 9663 | 33048 | -0.8021 | 0.0000 | |
| GSE53624 | LPIN2 | 9663 | 33048 | -1.0407 | 0.0000 | |
| GSE63941 | LPIN2 | 9663 | 202460_s_at | -2.0427 | 0.0137 | |
| GSE77861 | LPIN2 | 9663 | 202460_s_at | -0.6748 | 0.0414 | |
| GSE97050 | LPIN2 | 9663 | A_24_P301557 | 0.0186 | 0.9661 | |
| SRP007169 | LPIN2 | 9663 | RNAseq | -1.2895 | 0.0193 | |
| SRP008496 | LPIN2 | 9663 | RNAseq | -1.8037 | 0.0000 | |
| SRP064894 | LPIN2 | 9663 | RNAseq | -0.7344 | 0.0262 | |
| SRP133303 | LPIN2 | 9663 | RNAseq | -0.4021 | 0.0583 | |
| SRP159526 | LPIN2 | 9663 | RNAseq | -0.4059 | 0.2611 | |
| SRP193095 | LPIN2 | 9663 | RNAseq | -1.3516 | 0.0000 | |
| SRP219564 | LPIN2 | 9663 | RNAseq | -0.5229 | 0.2350 | |
| TCGA | LPIN2 | 9663 | RNAseq | -0.6350 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by LPIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPIN2 | 9663 | 7 | 2 | 21 | |
| GSE20123 | LPIN2 | 9663 | 7 | 2 | 21 | |
| GSE43470 | LPIN2 | 9663 | 2 | 5 | 36 | |
| GSE46452 | LPIN2 | 9663 | 3 | 20 | 36 | |
| GSE47630 | LPIN2 | 9663 | 8 | 17 | 15 | |
| GSE54993 | LPIN2 | 9663 | 6 | 4 | 60 | |
| GSE54994 | LPIN2 | 9663 | 11 | 8 | 34 | |
| GSE60625 | LPIN2 | 9663 | 0 | 4 | 7 | |
| GSE74703 | LPIN2 | 9663 | 2 | 3 | 31 | |
| GSE74704 | LPIN2 | 9663 | 5 | 2 | 13 | |
| TCGA | LPIN2 | 9663 | 35 | 18 | 43 |
Total number of gains: 86; Total number of losses: 85; Total Number of normals: 317.
Somatic mutations of LPIN2:
Generating mutation plots.
Highly correlated genes for LPIN2:
Showing top 20/829 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPIN2 | ZNF681 | 0.834568 | 3 | 0 | 3 |
| LPIN2 | CCNY | 0.763056 | 3 | 0 | 3 |
| LPIN2 | VPS53 | 0.754224 | 3 | 0 | 3 |
| LPIN2 | MRPL20 | 0.747845 | 3 | 0 | 3 |
| LPIN2 | PPP4R2 | 0.74641 | 4 | 0 | 4 |
| LPIN2 | RBM15B | 0.740901 | 3 | 0 | 3 |
| LPIN2 | RRAGB | 0.727136 | 3 | 0 | 3 |
| LPIN2 | DCP1B | 0.725204 | 3 | 0 | 3 |
| LPIN2 | IMPACT | 0.718596 | 3 | 0 | 3 |
| LPIN2 | SLC35B3 | 0.718389 | 4 | 0 | 4 |
| LPIN2 | ZFP62 | 0.708235 | 3 | 0 | 3 |
| LPIN2 | CHL1 | 0.705835 | 3 | 0 | 3 |
| LPIN2 | CNST | 0.705746 | 4 | 0 | 4 |
| LPIN2 | COG3 | 0.704129 | 3 | 0 | 3 |
| LPIN2 | ESYT2 | 0.703329 | 4 | 0 | 3 |
| LPIN2 | MLLT3 | 0.697635 | 3 | 0 | 3 |
| LPIN2 | CAPZA2 | 0.694465 | 3 | 0 | 3 |
| LPIN2 | POLR3GL | 0.691781 | 3 | 0 | 3 |
| LPIN2 | C5orf51 | 0.690137 | 3 | 0 | 3 |
| LPIN2 | ABHD12 | 0.689984 | 4 | 0 | 3 |
For details and further investigation, click here
