| Full name: synaptojanin 1 | Alias Symbol: INPP5G|PARK20 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 8867 | HGNC ID: HGNC:11503 | Ensembl Gene: ENSG00000159082 | OMIM ID: 604297 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNJ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNJ1 | 8867 | 212990_at | 0.1077 | 0.8358 | |
| GSE20347 | SYNJ1 | 8867 | 212990_at | -0.2103 | 0.1343 | |
| GSE23400 | SYNJ1 | 8867 | 212990_at | -0.0161 | 0.8232 | |
| GSE26886 | SYNJ1 | 8867 | 212990_at | -0.2223 | 0.5597 | |
| GSE29001 | SYNJ1 | 8867 | 212990_at | 0.0980 | 0.8680 | |
| GSE38129 | SYNJ1 | 8867 | 212990_at | -0.2573 | 0.0574 | |
| GSE45670 | SYNJ1 | 8867 | 212990_at | -0.1004 | 0.5466 | |
| GSE53622 | SYNJ1 | 8867 | 16041 | -0.2869 | 0.0014 | |
| GSE53624 | SYNJ1 | 8867 | 16041 | -0.2880 | 0.0022 | |
| GSE63941 | SYNJ1 | 8867 | 212990_at | -1.0410 | 0.1160 | |
| GSE77861 | SYNJ1 | 8867 | 207594_s_at | -0.1236 | 0.1974 | |
| GSE97050 | SYNJ1 | 8867 | A_23_P324718 | 0.0423 | 0.8499 | |
| SRP007169 | SYNJ1 | 8867 | RNAseq | 0.6725 | 0.0933 | |
| SRP008496 | SYNJ1 | 8867 | RNAseq | 0.1147 | 0.7028 | |
| SRP064894 | SYNJ1 | 8867 | RNAseq | 0.2088 | 0.4765 | |
| SRP133303 | SYNJ1 | 8867 | RNAseq | -0.0579 | 0.7199 | |
| SRP159526 | SYNJ1 | 8867 | RNAseq | -0.4359 | 0.1276 | |
| SRP193095 | SYNJ1 | 8867 | RNAseq | -0.0796 | 0.4278 | |
| SRP219564 | SYNJ1 | 8867 | RNAseq | 0.0057 | 0.9826 | |
| TCGA | SYNJ1 | 8867 | RNAseq | -0.1523 | 0.0139 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYNJ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYNJ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNJ1 | 8867 | 2 | 7 | 21 | |
| GSE20123 | SYNJ1 | 8867 | 2 | 8 | 20 | |
| GSE43470 | SYNJ1 | 8867 | 3 | 9 | 31 | |
| GSE46452 | SYNJ1 | 8867 | 1 | 21 | 37 | |
| GSE47630 | SYNJ1 | 8867 | 6 | 17 | 17 | |
| GSE54993 | SYNJ1 | 8867 | 9 | 1 | 60 | |
| GSE54994 | SYNJ1 | 8867 | 1 | 8 | 44 | |
| GSE60625 | SYNJ1 | 8867 | 0 | 0 | 11 | |
| GSE74703 | SYNJ1 | 8867 | 3 | 6 | 27 | |
| GSE74704 | SYNJ1 | 8867 | 1 | 4 | 15 | |
| TCGA | SYNJ1 | 8867 | 9 | 36 | 51 |
Total number of gains: 37; Total number of losses: 117; Total Number of normals: 334.
Somatic mutations of SYNJ1:
Generating mutation plots.
Highly correlated genes for SYNJ1:
Showing top 20/600 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNJ1 | POP5 | 0.771808 | 3 | 0 | 3 |
| SYNJ1 | ZNF578 | 0.758204 | 3 | 0 | 3 |
| SYNJ1 | ZNF334 | 0.730846 | 3 | 0 | 3 |
| SYNJ1 | MON1A | 0.729808 | 3 | 0 | 3 |
| SYNJ1 | GIMAP5 | 0.723238 | 3 | 0 | 3 |
| SYNJ1 | CLCC1 | 0.722912 | 4 | 0 | 4 |
| SYNJ1 | MSH2 | 0.707987 | 3 | 0 | 3 |
| SYNJ1 | C21orf91 | 0.707416 | 3 | 0 | 3 |
| SYNJ1 | LMBRD2 | 0.706927 | 5 | 0 | 4 |
| SYNJ1 | AP3S2 | 0.705724 | 3 | 0 | 3 |
| SYNJ1 | THAP2 | 0.705609 | 4 | 0 | 4 |
| SYNJ1 | SCLT1 | 0.699106 | 3 | 0 | 3 |
| SYNJ1 | GNB4 | 0.697024 | 3 | 0 | 3 |
| SYNJ1 | GOLGA5 | 0.696812 | 4 | 0 | 3 |
| SYNJ1 | MEA1 | 0.694558 | 3 | 0 | 3 |
| SYNJ1 | ANKRD54 | 0.693347 | 3 | 0 | 3 |
| SYNJ1 | TXNDC16 | 0.691689 | 4 | 0 | 4 |
| SYNJ1 | FOXP4 | 0.689965 | 3 | 0 | 3 |
| SYNJ1 | SPA17 | 0.685939 | 3 | 0 | 3 |
| SYNJ1 | CDC37 | 0.685083 | 3 | 0 | 3 |
For details and further investigation, click here
