| Full name: zinc finger protein 462 | Alias Symbol: DKFZP762N2316|KIAA1803|Zfp462 | ||
| Type: protein-coding gene | Cytoband: 9q31.2 | ||
| Entrez ID: 58499 | HGNC ID: HGNC:21684 | Ensembl Gene: ENSG00000148143 | OMIM ID: 617371 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF462:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF462 | 58499 | 226575_at | -0.6277 | 0.4778 | |
| GSE26886 | ZNF462 | 58499 | 226575_at | 0.1328 | 0.7030 | |
| GSE45670 | ZNF462 | 58499 | 226575_at | -0.3135 | 0.1540 | |
| GSE53622 | ZNF462 | 58499 | 75343 | -0.5407 | 0.0000 | |
| GSE53624 | ZNF462 | 58499 | 75343 | -0.4793 | 0.0000 | |
| GSE63941 | ZNF462 | 58499 | 226575_at | 0.0200 | 0.9803 | |
| GSE77861 | ZNF462 | 58499 | 226575_at | 0.0041 | 0.9880 | |
| GSE97050 | ZNF462 | 58499 | A_23_P60499 | -0.4651 | 0.3924 | |
| SRP007169 | ZNF462 | 58499 | RNAseq | 0.5443 | 0.1582 | |
| SRP008496 | ZNF462 | 58499 | RNAseq | 0.6310 | 0.0414 | |
| SRP064894 | ZNF462 | 58499 | RNAseq | -0.8184 | 0.0008 | |
| SRP133303 | ZNF462 | 58499 | RNAseq | -0.8324 | 0.0020 | |
| SRP159526 | ZNF462 | 58499 | RNAseq | -0.2843 | 0.5749 | |
| SRP193095 | ZNF462 | 58499 | RNAseq | -0.4957 | 0.0103 | |
| SRP219564 | ZNF462 | 58499 | RNAseq | -0.7903 | 0.1232 | |
| TCGA | ZNF462 | 58499 | RNAseq | 0.2299 | 0.0370 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF462 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF462:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF462 | 58499 | 4 | 10 | 16 | |
| GSE20123 | ZNF462 | 58499 | 5 | 9 | 16 | |
| GSE43470 | ZNF462 | 58499 | 7 | 3 | 33 | |
| GSE46452 | ZNF462 | 58499 | 6 | 13 | 40 | |
| GSE47630 | ZNF462 | 58499 | 1 | 17 | 22 | |
| GSE54993 | ZNF462 | 58499 | 3 | 3 | 64 | |
| GSE54994 | ZNF462 | 58499 | 9 | 10 | 34 | |
| GSE60625 | ZNF462 | 58499 | 0 | 0 | 11 | |
| GSE74703 | ZNF462 | 58499 | 6 | 3 | 27 | |
| GSE74704 | ZNF462 | 58499 | 2 | 6 | 12 | |
| TCGA | ZNF462 | 58499 | 26 | 21 | 49 |
Total number of gains: 69; Total number of losses: 95; Total Number of normals: 324.
Somatic mutations of ZNF462:
Generating mutation plots.
Highly correlated genes for ZNF462:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF462 | CDC42BPA | 0.722392 | 3 | 0 | 3 |
| ZNF462 | ZNF566 | 0.711874 | 3 | 0 | 3 |
| ZNF462 | ZNF721 | 0.690777 | 3 | 0 | 3 |
| ZNF462 | DDX42 | 0.685805 | 3 | 0 | 3 |
| ZNF462 | NUDT17 | 0.683797 | 3 | 0 | 3 |
| ZNF462 | NDST1 | 0.674476 | 3 | 0 | 3 |
| ZNF462 | ZNF461 | 0.673662 | 3 | 0 | 3 |
| ZNF462 | RXRA | 0.671496 | 3 | 0 | 3 |
| ZNF462 | ZBTB5 | 0.667311 | 3 | 0 | 3 |
| ZNF462 | SEPSECS | 0.655189 | 4 | 0 | 3 |
| ZNF462 | MEGF6 | 0.647326 | 3 | 0 | 3 |
| ZNF462 | PPIG | 0.641888 | 3 | 0 | 3 |
| ZNF462 | ZZEF1 | 0.640776 | 4 | 0 | 3 |
| ZNF462 | COBLL1 | 0.635303 | 3 | 0 | 3 |
| ZNF462 | FAM193B | 0.632136 | 3 | 0 | 3 |
| ZNF462 | UPF3A | 0.631425 | 4 | 0 | 3 |
| ZNF462 | MRPS31 | 0.620734 | 3 | 0 | 3 |
| ZNF462 | CREG1 | 0.61998 | 3 | 0 | 3 |
| ZNF462 | CDC16 | 0.618676 | 4 | 0 | 3 |
| ZNF462 | PKIA | 0.612298 | 4 | 0 | 3 |
For details and further investigation, click here
