| Full name: mitochondrial ribosomal protein S31 | Alias Symbol: IMOGN38 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 10240 | HGNC ID: HGNC:16632 | Ensembl Gene: ENSG00000102738 | OMIM ID: 611992 |
| Drug and gene relationship at DGIdb | |||
Expression of MRPS31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS31 | 10240 | 212603_at | -0.2829 | 0.6423 | |
| GSE20347 | MRPS31 | 10240 | 212603_at | -0.3770 | 0.0019 | |
| GSE23400 | MRPS31 | 10240 | 212603_at | 0.0172 | 0.8288 | |
| GSE26886 | MRPS31 | 10240 | 212603_at | 0.6714 | 0.0061 | |
| GSE29001 | MRPS31 | 10240 | 212603_at | -0.3176 | 0.3574 | |
| GSE38129 | MRPS31 | 10240 | 212603_at | -0.2740 | 0.0023 | |
| GSE45670 | MRPS31 | 10240 | 212603_at | -0.0614 | 0.5985 | |
| GSE53622 | MRPS31 | 10240 | 36449 | -0.2909 | 0.0000 | |
| GSE53624 | MRPS31 | 10240 | 36449 | -0.2126 | 0.0000 | |
| GSE63941 | MRPS31 | 10240 | 212603_at | 0.8558 | 0.0072 | |
| GSE77861 | MRPS31 | 10240 | 212603_at | -0.0928 | 0.7142 | |
| GSE97050 | MRPS31 | 10240 | A_23_P162807 | -0.0419 | 0.8533 | |
| SRP007169 | MRPS31 | 10240 | RNAseq | -0.3480 | 0.6995 | |
| SRP064894 | MRPS31 | 10240 | RNAseq | -0.0988 | 0.5464 | |
| SRP133303 | MRPS31 | 10240 | RNAseq | -0.4335 | 0.0012 | |
| SRP159526 | MRPS31 | 10240 | RNAseq | -0.7408 | 0.0002 | |
| SRP193095 | MRPS31 | 10240 | RNAseq | -0.5049 | 0.0000 | |
| SRP219564 | MRPS31 | 10240 | RNAseq | -0.5414 | 0.0477 | |
| TCGA | MRPS31 | 10240 | RNAseq | -0.0247 | 0.7081 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS31 | 10240 | 0 | 15 | 15 | |
| GSE20123 | MRPS31 | 10240 | 0 | 14 | 16 | |
| GSE43470 | MRPS31 | 10240 | 3 | 13 | 27 | |
| GSE46452 | MRPS31 | 10240 | 0 | 33 | 26 | |
| GSE47630 | MRPS31 | 10240 | 2 | 27 | 11 | |
| GSE54993 | MRPS31 | 10240 | 12 | 2 | 56 | |
| GSE54994 | MRPS31 | 10240 | 1 | 16 | 36 | |
| GSE60625 | MRPS31 | 10240 | 0 | 3 | 8 | |
| GSE74703 | MRPS31 | 10240 | 3 | 10 | 23 | |
| GSE74704 | MRPS31 | 10240 | 0 | 11 | 9 | |
| TCGA | MRPS31 | 10240 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 184; Total Number of normals: 276.
Somatic mutations of MRPS31:
Generating mutation plots.
Highly correlated genes for MRPS31:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS31 | DNAJC1 | 0.786478 | 3 | 0 | 3 |
| MRPS31 | SIN3A | 0.783125 | 3 | 0 | 3 |
| MRPS31 | INTS4 | 0.778864 | 3 | 0 | 3 |
| MRPS31 | GNPAT | 0.757769 | 3 | 0 | 3 |
| MRPS31 | MARK1 | 0.741655 | 3 | 0 | 3 |
| MRPS31 | EIF3E | 0.731427 | 3 | 0 | 3 |
| MRPS31 | PLEKHH1 | 0.729242 | 4 | 0 | 3 |
| MRPS31 | ZNF585A | 0.728781 | 3 | 0 | 3 |
| MRPS31 | CDADC1 | 0.727614 | 3 | 0 | 3 |
| MRPS31 | NMT1 | 0.726846 | 3 | 0 | 3 |
| MRPS31 | EIF2S2 | 0.722922 | 3 | 0 | 3 |
| MRPS31 | CPSF6 | 0.717232 | 3 | 0 | 3 |
| MRPS31 | STARD3NL | 0.716375 | 3 | 0 | 3 |
| MRPS31 | UHRF1BP1 | 0.712681 | 3 | 0 | 3 |
| MRPS31 | PGLS | 0.709958 | 3 | 0 | 3 |
| MRPS31 | ACER3 | 0.70116 | 3 | 0 | 3 |
| MRPS31 | GNG5 | 0.699682 | 3 | 0 | 3 |
| MRPS31 | SNW1 | 0.695597 | 4 | 0 | 4 |
| MRPS31 | F12 | 0.691869 | 3 | 0 | 3 |
| MRPS31 | CYCS | 0.691571 | 3 | 0 | 3 |
For details and further investigation, click here
