| Full name: zinc finger and BTB domain containing 5 | Alias Symbol: KIAA0354 | ||
| Type: protein-coding gene | Cytoband: 9p13.2 | ||
| Entrez ID: 9925 | HGNC ID: HGNC:23836 | Ensembl Gene: ENSG00000168795 | OMIM ID: 616590 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB5 | 9925 | 203026_at | -0.6415 | 0.1161 | |
| GSE20347 | ZBTB5 | 9925 | 203026_at | -0.7479 | 0.0000 | |
| GSE23400 | ZBTB5 | 9925 | 203026_at | -0.4463 | 0.0000 | |
| GSE26886 | ZBTB5 | 9925 | 203026_at | -1.0804 | 0.0000 | |
| GSE29001 | ZBTB5 | 9925 | 203026_at | -0.5698 | 0.0152 | |
| GSE38129 | ZBTB5 | 9925 | 203026_at | -0.4697 | 0.0026 | |
| GSE45670 | ZBTB5 | 9925 | 203026_at | -0.4929 | 0.0051 | |
| GSE53622 | ZBTB5 | 9925 | 20296 | -0.9198 | 0.0000 | |
| GSE53624 | ZBTB5 | 9925 | 20296 | -0.8861 | 0.0000 | |
| GSE63941 | ZBTB5 | 9925 | 203026_at | 0.5377 | 0.2749 | |
| GSE77861 | ZBTB5 | 9925 | 203026_at | -0.7682 | 0.0027 | |
| GSE97050 | ZBTB5 | 9925 | A_23_P216476 | -0.5179 | 0.2296 | |
| SRP007169 | ZBTB5 | 9925 | RNAseq | -1.4404 | 0.0001 | |
| SRP008496 | ZBTB5 | 9925 | RNAseq | -0.9193 | 0.0003 | |
| SRP064894 | ZBTB5 | 9925 | RNAseq | -1.0759 | 0.0000 | |
| SRP133303 | ZBTB5 | 9925 | RNAseq | -1.2123 | 0.0000 | |
| SRP159526 | ZBTB5 | 9925 | RNAseq | -0.9170 | 0.0000 | |
| SRP193095 | ZBTB5 | 9925 | RNAseq | -1.1990 | 0.0000 | |
| SRP219564 | ZBTB5 | 9925 | RNAseq | -0.3940 | 0.4700 | |
| TCGA | ZBTB5 | 9925 | RNAseq | 0.0039 | 0.9516 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ZBTB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB5 | 9925 | 3 | 13 | 14 | |
| GSE20123 | ZBTB5 | 9925 | 3 | 13 | 14 | |
| GSE43470 | ZBTB5 | 9925 | 1 | 12 | 30 | |
| GSE46452 | ZBTB5 | 9925 | 6 | 15 | 38 | |
| GSE47630 | ZBTB5 | 9925 | 1 | 20 | 19 | |
| GSE54993 | ZBTB5 | 9925 | 6 | 0 | 64 | |
| GSE54994 | ZBTB5 | 9925 | 5 | 13 | 35 | |
| GSE60625 | ZBTB5 | 9925 | 0 | 0 | 11 | |
| GSE74703 | ZBTB5 | 9925 | 1 | 8 | 27 | |
| GSE74704 | ZBTB5 | 9925 | 0 | 10 | 10 | |
| TCGA | ZBTB5 | 9925 | 14 | 44 | 38 |
Total number of gains: 40; Total number of losses: 148; Total Number of normals: 300.
Somatic mutations of ZBTB5:
Generating mutation plots.
Highly correlated genes for ZBTB5:
Showing top 20/1540 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB5 | SNORA68 | 0.809644 | 4 | 0 | 4 |
| ZBTB5 | GBP6 | 0.776685 | 4 | 0 | 4 |
| ZBTB5 | SAMD5 | 0.773907 | 7 | 0 | 7 |
| ZBTB5 | HDHD2 | 0.770677 | 5 | 0 | 5 |
| ZBTB5 | SFTA2 | 0.769706 | 4 | 0 | 4 |
| ZBTB5 | CGNL1 | 0.763676 | 7 | 0 | 7 |
| ZBTB5 | PAQR8 | 0.763097 | 7 | 0 | 7 |
| ZBTB5 | SH3BGRL2 | 0.761327 | 7 | 0 | 7 |
| ZBTB5 | NAGK | 0.760936 | 10 | 0 | 10 |
| ZBTB5 | BRK1 | 0.758578 | 7 | 0 | 7 |
| ZBTB5 | SLC46A2 | 0.758459 | 7 | 0 | 7 |
| ZBTB5 | SPINK7 | 0.754633 | 6 | 0 | 6 |
| ZBTB5 | KLB | 0.75361 | 6 | 0 | 6 |
| ZBTB5 | PLEKHA7 | 0.75303 | 7 | 0 | 7 |
| ZBTB5 | USP54 | 0.750266 | 7 | 0 | 7 |
| ZBTB5 | FCHO2 | 0.748186 | 7 | 0 | 7 |
| ZBTB5 | C18orf25 | 0.747988 | 11 | 0 | 11 |
| ZBTB5 | TMEM218 | 0.747044 | 3 | 0 | 3 |
| ZBTB5 | ZNF214 | 0.746756 | 4 | 0 | 4 |
| ZBTB5 | SHROOM3 | 0.745682 | 7 | 0 | 7 |
For details and further investigation, click here
