| Full name: WASP family member 2 | Alias Symbol: WAVE2|SCAR2 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 10163 | HGNC ID: HGNC:12733 | Ensembl Gene: ENSG00000158195 | OMIM ID: 605875 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
WASF2 involved pathways:
Expression of WASF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WASF2 | 10163 | 224562_at | -0.0649 | 0.8649 | |
| GSE20347 | WASF2 | 10163 | 221725_at | -0.6177 | 0.0003 | |
| GSE23400 | WASF2 | 10163 | 221725_at | -0.4457 | 0.0000 | |
| GSE26886 | WASF2 | 10163 | 221725_at | -1.3384 | 0.0000 | |
| GSE29001 | WASF2 | 10163 | 221725_at | -0.7480 | 0.0009 | |
| GSE38129 | WASF2 | 10163 | 221725_at | -0.6038 | 0.0000 | |
| GSE45670 | WASF2 | 10163 | 224562_at | -0.1729 | 0.3067 | |
| GSE53622 | WASF2 | 10163 | 110634 | -0.8875 | 0.0000 | |
| GSE53624 | WASF2 | 10163 | 110634 | -0.6143 | 0.0000 | |
| GSE63941 | WASF2 | 10163 | 224562_at | 0.3938 | 0.2973 | |
| GSE77861 | WASF2 | 10163 | 224562_at | -0.2423 | 0.5243 | |
| GSE97050 | WASF2 | 10163 | A_24_P76546 | -0.5656 | 0.1162 | |
| SRP007169 | WASF2 | 10163 | RNAseq | -0.8819 | 0.0220 | |
| SRP008496 | WASF2 | 10163 | RNAseq | -1.2067 | 0.0000 | |
| SRP064894 | WASF2 | 10163 | RNAseq | -0.7458 | 0.0000 | |
| SRP133303 | WASF2 | 10163 | RNAseq | -0.6276 | 0.0014 | |
| SRP159526 | WASF2 | 10163 | RNAseq | -0.8107 | 0.0002 | |
| SRP193095 | WASF2 | 10163 | RNAseq | -0.8154 | 0.0000 | |
| SRP219564 | WASF2 | 10163 | RNAseq | -1.0478 | 0.0084 | |
| TCGA | WASF2 | 10163 | RNAseq | -0.0052 | 0.9094 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by WASF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WASF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WASF2 | 10163 | 0 | 6 | 24 | |
| GSE20123 | WASF2 | 10163 | 0 | 5 | 25 | |
| GSE43470 | WASF2 | 10163 | 4 | 6 | 33 | |
| GSE46452 | WASF2 | 10163 | 5 | 1 | 53 | |
| GSE47630 | WASF2 | 10163 | 8 | 3 | 29 | |
| GSE54993 | WASF2 | 10163 | 2 | 1 | 67 | |
| GSE54994 | WASF2 | 10163 | 10 | 4 | 39 | |
| GSE60625 | WASF2 | 10163 | 0 | 0 | 11 | |
| GSE74703 | WASF2 | 10163 | 3 | 4 | 29 | |
| GSE74704 | WASF2 | 10163 | 0 | 0 | 20 | |
| TCGA | WASF2 | 10163 | 11 | 23 | 62 |
Total number of gains: 43; Total number of losses: 53; Total Number of normals: 392.
Somatic mutations of WASF2:
Generating mutation plots.
Highly correlated genes for WASF2:
Showing top 20/1060 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WASF2 | ZNF175 | 0.809468 | 3 | 0 | 3 |
| WASF2 | RSPH3 | 0.789971 | 3 | 0 | 3 |
| WASF2 | ULK3 | 0.780985 | 5 | 0 | 5 |
| WASF2 | UQCRC2 | 0.773253 | 3 | 0 | 3 |
| WASF2 | GGA3 | 0.769593 | 4 | 0 | 4 |
| WASF2 | ZNF681 | 0.748805 | 3 | 0 | 3 |
| WASF2 | ZFAND6 | 0.745226 | 3 | 0 | 3 |
| WASF2 | NIPSNAP3A | 0.740845 | 3 | 0 | 3 |
| WASF2 | DDI2 | 0.740676 | 3 | 0 | 3 |
| WASF2 | ANO8 | 0.740201 | 3 | 0 | 3 |
| WASF2 | TADA3 | 0.740143 | 3 | 0 | 3 |
| WASF2 | CHMP1B | 0.726645 | 3 | 0 | 3 |
| WASF2 | AP3M1 | 0.724393 | 3 | 0 | 3 |
| WASF2 | TXLNA | 0.720606 | 3 | 0 | 3 |
| WASF2 | FAM71F2 | 0.719848 | 3 | 0 | 3 |
| WASF2 | TAB3 | 0.717958 | 4 | 0 | 4 |
| WASF2 | FCHO2 | 0.717902 | 5 | 0 | 5 |
| WASF2 | KRT78 | 0.716965 | 4 | 0 | 4 |
| WASF2 | ABLIM2 | 0.714994 | 6 | 0 | 5 |
| WASF2 | CNFN | 0.712223 | 4 | 0 | 4 |
For details and further investigation, click here
