| Full name: metastasis associated 1 family member 3 | Alias Symbol: KIAA1266 | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 57504 | HGNC ID: HGNC:23784 | Ensembl Gene: ENSG00000057935 | OMIM ID: 609050 |
| Drug and gene relationship at DGIdb | |||
Expression of MTA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTA3 | 57504 | 223311_s_at | -0.2401 | 0.6144 | |
| GSE26886 | MTA3 | 57504 | 223311_s_at | -1.2981 | 0.0000 | |
| GSE45670 | MTA3 | 57504 | 223311_s_at | -0.0866 | 0.5835 | |
| GSE53622 | MTA3 | 57504 | 85812 | -0.2046 | 0.0011 | |
| GSE53624 | MTA3 | 57504 | 85812 | -0.3224 | 0.0000 | |
| GSE63941 | MTA3 | 57504 | 223311_s_at | 0.4123 | 0.2587 | |
| GSE77861 | MTA3 | 57504 | 223311_s_at | -0.2938 | 0.2159 | |
| GSE97050 | MTA3 | 57504 | A_23_P154522 | -0.2490 | 0.2990 | |
| SRP007169 | MTA3 | 57504 | RNAseq | -1.2352 | 0.0014 | |
| SRP008496 | MTA3 | 57504 | RNAseq | -1.0916 | 0.0000 | |
| SRP064894 | MTA3 | 57504 | RNAseq | -0.5160 | 0.0002 | |
| SRP133303 | MTA3 | 57504 | RNAseq | -0.3400 | 0.0339 | |
| SRP159526 | MTA3 | 57504 | RNAseq | -0.1379 | 0.5844 | |
| SRP193095 | MTA3 | 57504 | RNAseq | -0.4102 | 0.0002 | |
| SRP219564 | MTA3 | 57504 | RNAseq | -0.5146 | 0.1122 | |
| TCGA | MTA3 | 57504 | RNAseq | -0.0614 | 0.2252 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by MTA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTA3 | 57504 | 12 | 1 | 17 | |
| GSE20123 | MTA3 | 57504 | 11 | 1 | 18 | |
| GSE43470 | MTA3 | 57504 | 3 | 0 | 40 | |
| GSE46452 | MTA3 | 57504 | 1 | 4 | 54 | |
| GSE47630 | MTA3 | 57504 | 7 | 0 | 33 | |
| GSE54993 | MTA3 | 57504 | 0 | 5 | 65 | |
| GSE54994 | MTA3 | 57504 | 10 | 0 | 43 | |
| GSE60625 | MTA3 | 57504 | 0 | 3 | 8 | |
| GSE74703 | MTA3 | 57504 | 3 | 0 | 33 | |
| GSE74704 | MTA3 | 57504 | 10 | 1 | 9 | |
| TCGA | MTA3 | 57504 | 35 | 2 | 59 |
Total number of gains: 92; Total number of losses: 17; Total Number of normals: 379.
Somatic mutations of MTA3:
Generating mutation plots.
Highly correlated genes for MTA3:
Showing top 20/660 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTA3 | USP16 | 0.817143 | 3 | 0 | 3 |
| MTA3 | HDHD2 | 0.808925 | 3 | 0 | 3 |
| MTA3 | RAD23B | 0.806342 | 3 | 0 | 3 |
| MTA3 | ZNF717 | 0.802346 | 3 | 0 | 3 |
| MTA3 | CLIP4 | 0.796335 | 3 | 0 | 3 |
| MTA3 | XG | 0.783179 | 3 | 0 | 3 |
| MTA3 | PRPF38A | 0.771946 | 3 | 0 | 3 |
| MTA3 | HUS1 | 0.771222 | 3 | 0 | 3 |
| MTA3 | SREBF2 | 0.766308 | 3 | 0 | 3 |
| MTA3 | CHMP2B | 0.760981 | 4 | 0 | 4 |
| MTA3 | CTBS | 0.760016 | 3 | 0 | 3 |
| MTA3 | B3GAT2 | 0.754933 | 3 | 0 | 3 |
| MTA3 | PITPNM3 | 0.752469 | 3 | 0 | 3 |
| MTA3 | ZNF585B | 0.741295 | 3 | 0 | 3 |
| MTA3 | JDP2 | 0.740096 | 3 | 0 | 3 |
| MTA3 | APOB | 0.740009 | 3 | 0 | 3 |
| MTA3 | DDX52 | 0.738083 | 3 | 0 | 3 |
| MTA3 | UBA3 | 0.737918 | 4 | 0 | 4 |
| MTA3 | LNX2 | 0.731024 | 4 | 0 | 4 |
| MTA3 | FOXN1 | 0.728502 | 3 | 0 | 3 |
For details and further investigation, click here
