| Full name: zinc finger HIT-type containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 9326 | HGNC ID: HGNC:12309 | Ensembl Gene: ENSG00000273611 | OMIM ID: 604500 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNHIT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNHIT3 | 9326 | 212544_at | -0.0360 | 0.9348 | |
| GSE20347 | ZNHIT3 | 9326 | 212544_at | 0.3088 | 0.1554 | |
| GSE23400 | ZNHIT3 | 9326 | 212544_at | 0.5248 | 0.0000 | |
| GSE26886 | ZNHIT3 | 9326 | 212544_at | 0.3126 | 0.3167 | |
| GSE29001 | ZNHIT3 | 9326 | 212544_at | 0.3286 | 0.4976 | |
| GSE38129 | ZNHIT3 | 9326 | 212544_at | 0.4659 | 0.0145 | |
| GSE45670 | ZNHIT3 | 9326 | 212544_at | 0.0214 | 0.9074 | |
| GSE53622 | ZNHIT3 | 9326 | 82827 | 0.3369 | 0.0000 | |
| GSE53624 | ZNHIT3 | 9326 | 82827 | 0.3550 | 0.0000 | |
| GSE63941 | ZNHIT3 | 9326 | 212544_at | 0.5543 | 0.0499 | |
| GSE77861 | ZNHIT3 | 9326 | 212544_at | 0.3749 | 0.0656 | |
| GSE97050 | ZNHIT3 | 9326 | A_23_P383435 | 0.0481 | 0.8689 | |
| SRP007169 | ZNHIT3 | 9326 | RNAseq | -0.1715 | 0.6043 | |
| SRP008496 | ZNHIT3 | 9326 | RNAseq | -0.2668 | 0.2828 | |
| SRP064894 | ZNHIT3 | 9326 | RNAseq | 0.2090 | 0.3169 | |
| SRP133303 | ZNHIT3 | 9326 | RNAseq | 0.2251 | 0.1836 | |
| SRP159526 | ZNHIT3 | 9326 | RNAseq | 0.0339 | 0.9060 | |
| SRP193095 | ZNHIT3 | 9326 | RNAseq | -0.2761 | 0.0164 | |
| SRP219564 | ZNHIT3 | 9326 | RNAseq | -0.3358 | 0.0880 | |
| TCGA | ZNHIT3 | 9326 | RNAseq | 0.0733 | 0.1815 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNHIT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNHIT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNHIT3 | 9326 | 5 | 1 | 24 | |
| GSE20123 | ZNHIT3 | 9326 | 5 | 1 | 24 | |
| GSE43470 | ZNHIT3 | 9326 | 1 | 2 | 40 | |
| GSE46452 | ZNHIT3 | 9326 | 34 | 0 | 25 | |
| GSE47630 | ZNHIT3 | 9326 | 8 | 1 | 31 | |
| GSE54993 | ZNHIT3 | 9326 | 3 | 3 | 64 | |
| GSE54994 | ZNHIT3 | 9326 | 8 | 6 | 39 | |
| GSE60625 | ZNHIT3 | 9326 | 4 | 0 | 7 | |
| GSE74703 | ZNHIT3 | 9326 | 1 | 1 | 34 | |
| GSE74704 | ZNHIT3 | 9326 | 3 | 1 | 16 | |
| TCGA | ZNHIT3 | 9326 | 20 | 9 | 67 |
Total number of gains: 92; Total number of losses: 25; Total Number of normals: 371.
Somatic mutations of ZNHIT3:
Generating mutation plots.
Highly correlated genes for ZNHIT3:
Showing top 20/1066 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNHIT3 | MCPH1 | 0.760598 | 3 | 0 | 3 |
| ZNHIT3 | ZNF655 | 0.733513 | 3 | 0 | 3 |
| ZNHIT3 | SPOPL | 0.709627 | 3 | 0 | 3 |
| ZNHIT3 | MRPS18A | 0.704619 | 4 | 0 | 4 |
| ZNHIT3 | DCUN1D4 | 0.697376 | 3 | 0 | 3 |
| ZNHIT3 | CCNY | 0.695017 | 3 | 0 | 3 |
| ZNHIT3 | PARP8 | 0.690521 | 3 | 0 | 3 |
| ZNHIT3 | CEP70 | 0.688196 | 3 | 0 | 3 |
| ZNHIT3 | GTF3C4 | 0.687867 | 4 | 0 | 4 |
| ZNHIT3 | BCAS3 | 0.687266 | 4 | 0 | 4 |
| ZNHIT3 | ZNF830 | 0.682556 | 4 | 0 | 3 |
| ZNHIT3 | HSPA5 | 0.681316 | 6 | 0 | 6 |
| ZNHIT3 | PIGS | 0.681271 | 3 | 0 | 3 |
| ZNHIT3 | ANKRD40 | 0.679118 | 4 | 0 | 3 |
| ZNHIT3 | CYFIP1 | 0.677598 | 3 | 0 | 3 |
| ZNHIT3 | BOD1 | 0.677134 | 6 | 0 | 5 |
| ZNHIT3 | CCDC28A | 0.672052 | 5 | 0 | 5 |
| ZNHIT3 | WDR77 | 0.671111 | 3 | 0 | 3 |
| ZNHIT3 | NDUFA12 | 0.670199 | 5 | 0 | 5 |
| ZNHIT3 | ATG3 | 0.667602 | 6 | 0 | 6 |
For details and further investigation, click here
