| Full name: general transcription factor IIIC subunit 4 | Alias Symbol: TFIIIC90|KAT12 | ||
| Type: protein-coding gene | Cytoband: 9q34.13 | ||
| Entrez ID: 9329 | HGNC ID: HGNC:4667 | Ensembl Gene: ENSG00000125484 | OMIM ID: 604892 |
| Drug and gene relationship at DGIdb | |||
Expression of GTF3C4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF3C4 | 9329 | 225543_at | 0.2114 | 0.7071 | |
| GSE20347 | GTF3C4 | 9329 | 219198_at | 0.3206 | 0.0043 | |
| GSE23400 | GTF3C4 | 9329 | 219198_at | 0.2033 | 0.0001 | |
| GSE26886 | GTF3C4 | 9329 | 225543_at | 0.1881 | 0.5499 | |
| GSE29001 | GTF3C4 | 9329 | 219198_at | 0.1882 | 0.1134 | |
| GSE38129 | GTF3C4 | 9329 | 219198_at | 0.3856 | 0.0004 | |
| GSE45670 | GTF3C4 | 9329 | 225543_at | -0.0347 | 0.8588 | |
| GSE53622 | GTF3C4 | 9329 | 9446 | 0.1360 | 0.0855 | |
| GSE53624 | GTF3C4 | 9329 | 110938 | 0.4229 | 0.0000 | |
| GSE63941 | GTF3C4 | 9329 | 225543_at | 0.0541 | 0.9377 | |
| GSE77861 | GTF3C4 | 9329 | 225543_at | 0.0946 | 0.4528 | |
| GSE97050 | GTF3C4 | 9329 | A_23_P20732 | 0.3301 | 0.3291 | |
| SRP007169 | GTF3C4 | 9329 | RNAseq | 0.8148 | 0.0488 | |
| SRP008496 | GTF3C4 | 9329 | RNAseq | 0.9093 | 0.0001 | |
| SRP064894 | GTF3C4 | 9329 | RNAseq | 0.2474 | 0.2154 | |
| SRP133303 | GTF3C4 | 9329 | RNAseq | 0.3188 | 0.0648 | |
| SRP159526 | GTF3C4 | 9329 | RNAseq | 0.4660 | 0.0346 | |
| SRP193095 | GTF3C4 | 9329 | RNAseq | 0.1608 | 0.1106 | |
| SRP219564 | GTF3C4 | 9329 | RNAseq | 0.0598 | 0.8292 | |
| TCGA | GTF3C4 | 9329 | RNAseq | 0.1053 | 0.1233 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF3C4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF3C4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF3C4 | 9329 | 5 | 7 | 18 | |
| GSE20123 | GTF3C4 | 9329 | 5 | 7 | 18 | |
| GSE43470 | GTF3C4 | 9329 | 4 | 7 | 32 | |
| GSE46452 | GTF3C4 | 9329 | 6 | 13 | 40 | |
| GSE47630 | GTF3C4 | 9329 | 4 | 15 | 21 | |
| GSE54993 | GTF3C4 | 9329 | 3 | 3 | 64 | |
| GSE54994 | GTF3C4 | 9329 | 12 | 9 | 32 | |
| GSE60625 | GTF3C4 | 9329 | 0 | 0 | 11 | |
| GSE74703 | GTF3C4 | 9329 | 4 | 5 | 27 | |
| GSE74704 | GTF3C4 | 9329 | 3 | 5 | 12 | |
| TCGA | GTF3C4 | 9329 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of GTF3C4:
Generating mutation plots.
Highly correlated genes for GTF3C4:
Showing top 20/916 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF3C4 | MANEA | 0.784508 | 3 | 0 | 3 |
| GTF3C4 | DIP2B | 0.776317 | 3 | 0 | 3 |
| GTF3C4 | SLC30A7 | 0.773775 | 3 | 0 | 3 |
| GTF3C4 | TPM3 | 0.754797 | 3 | 0 | 3 |
| GTF3C4 | ACBD5 | 0.750822 | 3 | 0 | 3 |
| GTF3C4 | INTS10 | 0.74796 | 4 | 0 | 4 |
| GTF3C4 | KDELR2 | 0.74752 | 3 | 0 | 3 |
| GTF3C4 | RPP38 | 0.738323 | 4 | 0 | 4 |
| GTF3C4 | ZDHHC16 | 0.737779 | 4 | 0 | 4 |
| GTF3C4 | ANKIB1 | 0.735915 | 3 | 0 | 3 |
| GTF3C4 | ANKRD49 | 0.734761 | 3 | 0 | 3 |
| GTF3C4 | MAN1A2 | 0.733261 | 3 | 0 | 3 |
| GTF3C4 | TRUB1 | 0.726948 | 4 | 0 | 3 |
| GTF3C4 | CHAMP1 | 0.725933 | 3 | 0 | 3 |
| GTF3C4 | EID2 | 0.718595 | 3 | 0 | 3 |
| GTF3C4 | AASDHPPT | 0.713569 | 3 | 0 | 3 |
| GTF3C4 | ASCC3 | 0.713103 | 3 | 0 | 3 |
| GTF3C4 | LARS2 | 0.711289 | 3 | 0 | 3 |
| GTF3C4 | CHD2 | 0.711159 | 4 | 0 | 3 |
| GTF3C4 | PDRG1 | 0.708567 | 3 | 0 | 3 |
For details and further investigation, click here
