| Full name: centrosomal protein 70 | Alias Symbol: BITE|FLJ13036 | ||
| Type: protein-coding gene | Cytoband: 3q22.3 | ||
| Entrez ID: 80321 | HGNC ID: HGNC:29972 | Ensembl Gene: ENSG00000114107 | OMIM ID: 614310 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CEP70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP70 | 80321 | 219036_at | 0.7161 | 0.2257 | |
| GSE20347 | CEP70 | 80321 | 219036_at | 0.4916 | 0.0965 | |
| GSE23400 | CEP70 | 80321 | 219036_at | 0.1401 | 0.0508 | |
| GSE26886 | CEP70 | 80321 | 219036_at | -0.0291 | 0.9165 | |
| GSE29001 | CEP70 | 80321 | 219036_at | 0.5715 | 0.1521 | |
| GSE38129 | CEP70 | 80321 | 219036_at | 0.3465 | 0.1085 | |
| GSE45670 | CEP70 | 80321 | 219036_at | 0.1434 | 0.6031 | |
| GSE53622 | CEP70 | 80321 | 80427 | -0.0799 | 0.5179 | |
| GSE53624 | CEP70 | 80321 | 80427 | 0.1060 | 0.2592 | |
| GSE63941 | CEP70 | 80321 | 219036_at | 0.7100 | 0.0725 | |
| GSE77861 | CEP70 | 80321 | 219036_at | 0.1333 | 0.8553 | |
| GSE97050 | CEP70 | 80321 | A_23_P21473 | -0.2367 | 0.4980 | |
| SRP007169 | CEP70 | 80321 | RNAseq | 0.0330 | 0.9301 | |
| SRP008496 | CEP70 | 80321 | RNAseq | 0.1447 | 0.6401 | |
| SRP064894 | CEP70 | 80321 | RNAseq | 0.0113 | 0.9586 | |
| SRP133303 | CEP70 | 80321 | RNAseq | 0.4688 | 0.0066 | |
| SRP159526 | CEP70 | 80321 | RNAseq | 0.8736 | 0.0011 | |
| SRP193095 | CEP70 | 80321 | RNAseq | -0.0560 | 0.7412 | |
| SRP219564 | CEP70 | 80321 | RNAseq | -0.1662 | 0.5238 | |
| TCGA | CEP70 | 80321 | RNAseq | 0.0683 | 0.4038 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CEP70 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEP70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP70 | 80321 | 17 | 0 | 13 | |
| GSE20123 | CEP70 | 80321 | 17 | 0 | 13 | |
| GSE43470 | CEP70 | 80321 | 22 | 0 | 21 | |
| GSE46452 | CEP70 | 80321 | 15 | 4 | 40 | |
| GSE47630 | CEP70 | 80321 | 18 | 3 | 19 | |
| GSE54993 | CEP70 | 80321 | 2 | 8 | 60 | |
| GSE54994 | CEP70 | 80321 | 32 | 1 | 20 | |
| GSE60625 | CEP70 | 80321 | 0 | 6 | 5 | |
| GSE74703 | CEP70 | 80321 | 19 | 0 | 17 | |
| GSE74704 | CEP70 | 80321 | 11 | 0 | 9 | |
| TCGA | CEP70 | 80321 | 62 | 4 | 30 |
Total number of gains: 215; Total number of losses: 26; Total Number of normals: 247.
Somatic mutations of CEP70:
Generating mutation plots.
Highly correlated genes for CEP70:
Showing top 20/260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP70 | CLEC2B | 0.769798 | 3 | 0 | 3 |
| CEP70 | MRPL36 | 0.742301 | 3 | 0 | 3 |
| CEP70 | TRUB1 | 0.741365 | 3 | 0 | 3 |
| CEP70 | TCEA1 | 0.740377 | 3 | 0 | 3 |
| CEP70 | UGGT2 | 0.731703 | 3 | 0 | 3 |
| CEP70 | ASPH | 0.725239 | 3 | 0 | 3 |
| CEP70 | DPM1 | 0.724636 | 3 | 0 | 3 |
| CEP70 | ORC2 | 0.722267 | 3 | 0 | 3 |
| CEP70 | RBMXL1 | 0.72131 | 3 | 0 | 3 |
| CEP70 | SOX18 | 0.719481 | 3 | 0 | 3 |
| CEP70 | ARHGEF2 | 0.716024 | 3 | 0 | 3 |
| CEP70 | TTC21B | 0.71418 | 3 | 0 | 3 |
| CEP70 | MTRR | 0.697322 | 3 | 0 | 3 |
| CEP70 | BHLHB9 | 0.695501 | 5 | 0 | 5 |
| CEP70 | CAPN12 | 0.688846 | 3 | 0 | 3 |
| CEP70 | ZNHIT3 | 0.688196 | 3 | 0 | 3 |
| CEP70 | NENF | 0.687779 | 4 | 0 | 3 |
| CEP70 | CISD2 | 0.687462 | 4 | 0 | 3 |
| CEP70 | HACL1 | 0.687153 | 3 | 0 | 3 |
| CEP70 | UGDH | 0.687123 | 3 | 0 | 3 |
For details and further investigation, click here
