ZSWIM6

 

Full name: zinc finger SWIM-type containing 6 Alias Symbol: KIAA1577
Type: protein-coding gene Cytoband: 5q12.1
Entrez ID: 57688 HGNC ID: HGNC:29316 Ensembl Gene: ENSG00000130449 OMIM ID: 615951
Drug and gene relationship at DGIdb

 

Expression of ZSWIM6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZSWIM6 57688 226208_at -0.4486 0.3943
GSE26886 ZSWIM6 57688 226208_at -0.3440 0.1399
GSE45670 ZSWIM6 57688 226208_at -0.4010 0.0034
GSE53622 ZSWIM6 57688 72789 -0.5967 0.0000
GSE53624 ZSWIM6 57688 72789 -0.7932 0.0000
GSE63941 ZSWIM6 57688 226208_at -0.9390 0.1179
GSE77861 ZSWIM6 57688 226208_at -0.3551 0.0870
GSE97050 ZSWIM6 A_19_P00803333 -0.1025 0.6716
SRP007169 ZSWIM6 57688 RNAseq -1.0909 0.0061
SRP008496 ZSWIM6 57688 RNAseq -0.8981 0.0000
SRP064894 ZSWIM6 57688 RNAseq -0.9482 0.0023
SRP133303 ZSWIM6 57688 RNAseq -0.3132 0.0091
SRP159526 ZSWIM6 57688 RNAseq -0.7755 0.0241
SRP193095 ZSWIM6 57688 RNAseq -0.8501 0.0000
SRP219564 ZSWIM6 57688 RNAseq -0.4843 0.2753
TCGA ZSWIM6 57688 RNAseq -0.2731 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by ZSWIM6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZSWIM6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZSWIM6 57688 0 13 17
GSE20123 ZSWIM6 57688 0 13 17
GSE43470 ZSWIM6 57688 1 12 30
GSE46452 ZSWIM6 57688 0 28 31
GSE47630 ZSWIM6 57688 2 17 21
GSE54993 ZSWIM6 57688 8 1 61
GSE54994 ZSWIM6 57688 1 19 33
GSE60625 ZSWIM6 57688 0 0 11
GSE74703 ZSWIM6 57688 1 9 26
GSE74704 ZSWIM6 57688 0 6 14
TCGA ZSWIM6 57688 5 49 42

Total number of gains: 18; Total number of losses: 167; Total Number of normals: 303.  


 

Somatic mutations of ZSWIM6:

 

Generating mutation plots.

 

Highly correlated genes for ZSWIM6:

 

Showing top 20/791 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZSWIM6DLL10.750092303
ZSWIM6TBCA0.738022404
ZSWIM6ZFY0.73231303
ZSWIM6UCHL30.731635303
ZSWIM6PLXNA20.707533404
ZSWIM6CA130.702084303
ZSWIM6FPGT0.699695303
ZSWIM6NDUFA130.698025303
ZSWIM6UBE2R20.697694303
ZSWIM6TEX20.690131403
ZSWIM6BBIP10.687749403
ZSWIM6PDZD110.684161403
ZSWIM6HLA-DQB20.681957303
ZSWIM6ITPKC0.681867605
ZSWIM6RRAD0.681411404
ZSWIM6CHM0.680573303
ZSWIM6USP320.680027303
ZSWIM6NSA20.678951504
ZSWIM6SRGAP20.677509403
ZSWIM6ACADVL0.676478504

For details and further investigation, click here