| Full name: sec1 family domain containing 1 | Alias Symbol: RA410|KIAA0917|STXBP1L2|SLY1 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 23256 | HGNC ID: HGNC:20726 | Ensembl Gene: ENSG00000092108 | OMIM ID: 618207 |
| Drug and gene relationship at DGIdb | |||
Expression of SCFD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCFD1 | 23256 | 215548_s_at | 0.3284 | 0.6904 | |
| GSE20347 | SCFD1 | 23256 | 215548_s_at | -0.1780 | 0.2961 | |
| GSE23400 | SCFD1 | 23256 | 215548_s_at | 0.1748 | 0.0226 | |
| GSE26886 | SCFD1 | 23256 | 215548_s_at | -0.1300 | 0.5783 | |
| GSE29001 | SCFD1 | 23256 | 215548_s_at | -0.2682 | 0.5884 | |
| GSE38129 | SCFD1 | 23256 | 215548_s_at | -0.0343 | 0.8289 | |
| GSE45670 | SCFD1 | 23256 | 215548_s_at | 0.0032 | 0.9867 | |
| GSE53622 | SCFD1 | 23256 | 19508 | 0.0984 | 0.1046 | |
| GSE53624 | SCFD1 | 23256 | 19508 | 0.0111 | 0.8345 | |
| GSE63941 | SCFD1 | 23256 | 215548_s_at | -0.2368 | 0.6821 | |
| GSE77861 | SCFD1 | 23256 | 215548_s_at | -0.0249 | 0.9638 | |
| GSE97050 | SCFD1 | 23256 | A_33_P3311637 | 0.2526 | 0.2502 | |
| SRP007169 | SCFD1 | 23256 | RNAseq | -0.6260 | 0.0517 | |
| SRP008496 | SCFD1 | 23256 | RNAseq | -0.6503 | 0.0035 | |
| SRP064894 | SCFD1 | 23256 | RNAseq | -0.0718 | 0.6475 | |
| SRP133303 | SCFD1 | 23256 | RNAseq | 0.4826 | 0.0351 | |
| SRP159526 | SCFD1 | 23256 | RNAseq | -0.4893 | 0.0815 | |
| SRP193095 | SCFD1 | 23256 | RNAseq | -0.3871 | 0.0019 | |
| SRP219564 | SCFD1 | 23256 | RNAseq | 0.0392 | 0.9234 | |
| TCGA | SCFD1 | 23256 | RNAseq | 0.0278 | 0.5879 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCFD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCFD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCFD1 | 23256 | 9 | 4 | 17 | |
| GSE20123 | SCFD1 | 23256 | 9 | 4 | 17 | |
| GSE43470 | SCFD1 | 23256 | 10 | 2 | 31 | |
| GSE46452 | SCFD1 | 23256 | 16 | 2 | 41 | |
| GSE47630 | SCFD1 | 23256 | 11 | 10 | 19 | |
| GSE54993 | SCFD1 | 23256 | 3 | 11 | 56 | |
| GSE54994 | SCFD1 | 23256 | 19 | 5 | 29 | |
| GSE60625 | SCFD1 | 23256 | 0 | 2 | 9 | |
| GSE74703 | SCFD1 | 23256 | 9 | 2 | 25 | |
| GSE74704 | SCFD1 | 23256 | 3 | 3 | 14 | |
| TCGA | SCFD1 | 23256 | 31 | 14 | 51 |
Total number of gains: 120; Total number of losses: 59; Total Number of normals: 309.
Somatic mutations of SCFD1:
Generating mutation plots.
Highly correlated genes for SCFD1:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCFD1 | IRAK4 | 0.778183 | 3 | 0 | 3 |
| SCFD1 | BTF3L4 | 0.770392 | 3 | 0 | 3 |
| SCFD1 | C2orf76 | 0.756764 | 3 | 0 | 3 |
| SCFD1 | THOC1 | 0.742188 | 3 | 0 | 3 |
| SCFD1 | EXOC8 | 0.734229 | 3 | 0 | 3 |
| SCFD1 | NAA15 | 0.728475 | 3 | 0 | 3 |
| SCFD1 | VAMP3 | 0.726714 | 3 | 0 | 3 |
| SCFD1 | MRPS5 | 0.722151 | 3 | 0 | 3 |
| SCFD1 | BPNT1 | 0.720668 | 3 | 0 | 3 |
| SCFD1 | PTPN4 | 0.718515 | 3 | 0 | 3 |
| SCFD1 | SUB1 | 0.715303 | 3 | 0 | 3 |
| SCFD1 | ZNF562 | 0.71435 | 3 | 0 | 3 |
| SCFD1 | LRIF1 | 0.713791 | 3 | 0 | 3 |
| SCFD1 | EIF1AX | 0.712734 | 3 | 0 | 3 |
| SCFD1 | ZYG11A | 0.710625 | 3 | 0 | 3 |
| SCFD1 | FASTKD3 | 0.706965 | 3 | 0 | 3 |
| SCFD1 | COQ4 | 0.699863 | 3 | 0 | 3 |
| SCFD1 | DTD2 | 0.693577 | 3 | 0 | 3 |
| SCFD1 | PNP | 0.693528 | 6 | 0 | 6 |
| SCFD1 | CETN3 | 0.691186 | 3 | 0 | 3 |
For details and further investigation, click here
