| Full name: periostin | Alias Symbol: OSF-2|PN|periostin | ||
| Type: protein-coding gene | Cytoband: 13q13.3 | ||
| Entrez ID: 10631 | HGNC ID: HGNC:16953 | Ensembl Gene: ENSG00000133110 | OMIM ID: 608777 |
| Drug and gene relationship at DGIdb | |||
Expression of POSTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POSTN | 10631 | 210809_s_at | 1.7702 | 0.1335 | |
| GSE20347 | POSTN | 10631 | 210809_s_at | 3.8196 | 0.0000 | |
| GSE23400 | POSTN | 10631 | 210809_s_at | 3.2860 | 0.0000 | |
| GSE26886 | POSTN | 10631 | 210809_s_at | 5.4234 | 0.0000 | |
| GSE29001 | POSTN | 10631 | 210809_s_at | 3.2137 | 0.0000 | |
| GSE38129 | POSTN | 10631 | 210809_s_at | 3.5803 | 0.0000 | |
| GSE45670 | POSTN | 10631 | 210809_s_at | 0.3891 | 0.7699 | |
| GSE53622 | POSTN | 10631 | 50577 | 4.2345 | 0.0000 | |
| GSE53624 | POSTN | 10631 | 50577 | 4.0565 | 0.0000 | |
| GSE63941 | POSTN | 10631 | 210809_s_at | -7.7523 | 0.0001 | |
| GSE77861 | POSTN | 10631 | 210809_s_at | 1.6974 | 0.1883 | |
| GSE97050 | POSTN | 10631 | A_33_P3511265 | 3.6994 | 0.0454 | |
| SRP007169 | POSTN | 10631 | RNAseq | 8.0156 | 0.0000 | |
| SRP008496 | POSTN | 10631 | RNAseq | 7.8825 | 0.0000 | |
| SRP064894 | POSTN | 10631 | RNAseq | 4.4028 | 0.0000 | |
| SRP133303 | POSTN | 10631 | RNAseq | 4.8450 | 0.0000 | |
| SRP159526 | POSTN | 10631 | RNAseq | 3.0357 | 0.0000 | |
| SRP193095 | POSTN | 10631 | RNAseq | 2.2243 | 0.0009 | |
| TCGA | POSTN | 10631 | RNAseq | 0.1466 | 0.3044 |
Upregulated datasets: 14; Downregulated datasets: 1.
Survival by POSTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POSTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POSTN | 10631 | 0 | 16 | 14 | |
| GSE20123 | POSTN | 10631 | 0 | 15 | 15 | |
| GSE43470 | POSTN | 10631 | 3 | 13 | 27 | |
| GSE46452 | POSTN | 10631 | 0 | 33 | 26 | |
| GSE47630 | POSTN | 10631 | 2 | 27 | 11 | |
| GSE54993 | POSTN | 10631 | 12 | 2 | 56 | |
| GSE54994 | POSTN | 10631 | 1 | 17 | 35 | |
| GSE60625 | POSTN | 10631 | 0 | 3 | 8 | |
| GSE74703 | POSTN | 10631 | 3 | 10 | 23 | |
| GSE74704 | POSTN | 10631 | 0 | 12 | 8 | |
| TCGA | POSTN | 10631 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 188; Total Number of normals: 272.
Somatic mutations of POSTN:
Generating mutation plots.
Highly correlated genes for POSTN:
Showing top 20/1140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POSTN | COL3A1 | 0.902844 | 13 | 0 | 13 |
| POSTN | VCAN | 0.888697 | 13 | 0 | 13 |
| POSTN | COL6A3 | 0.88196 | 13 | 0 | 13 |
| POSTN | COL1A2 | 0.874786 | 13 | 0 | 13 |
| POSTN | SPARC | 0.87007 | 13 | 0 | 12 |
| POSTN | COL5A2 | 0.866567 | 13 | 0 | 13 |
| POSTN | COL5A1 | 0.851033 | 13 | 0 | 13 |
| POSTN | FAP | 0.834793 | 11 | 0 | 11 |
| POSTN | NID2 | 0.8319 | 10 | 0 | 10 |
| POSTN | SULF1 | 0.830334 | 13 | 0 | 13 |
| POSTN | FN1 | 0.820591 | 12 | 0 | 12 |
| POSTN | CTSK | 0.815203 | 13 | 0 | 13 |
| POSTN | THY1 | 0.815105 | 13 | 0 | 13 |
| POSTN | CDH11 | 0.813431 | 13 | 0 | 12 |
| POSTN | COL10A1 | 0.813204 | 12 | 0 | 12 |
| POSTN | CTHRC1 | 0.810349 | 9 | 0 | 9 |
| POSTN | THBS2 | 0.807716 | 13 | 0 | 13 |
| POSTN | MMP11 | 0.804136 | 10 | 0 | 10 |
| POSTN | BGN | 0.797528 | 13 | 0 | 13 |
| POSTN | INHBA | 0.787548 | 12 | 0 | 12 |
For details and further investigation, click here
