| Full name: cadherin 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p13.3 | ||
| Entrez ID: 1004 | HGNC ID: HGNC:1765 | Ensembl Gene: ENSG00000113361 | OMIM ID: 603007 |
| Drug and gene relationship at DGIdb | |||
Expression of CDH6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDH6 | 1004 | 214803_at | -0.2157 | 0.7396 | |
| GSE20347 | CDH6 | 1004 | 210601_at | 0.1189 | 0.2011 | |
| GSE23400 | CDH6 | 1004 | 210601_at | -0.0581 | 0.0774 | |
| GSE26886 | CDH6 | 1004 | 210601_at | 0.3170 | 0.0839 | |
| GSE29001 | CDH6 | 1004 | 214803_at | -0.4626 | 0.0199 | |
| GSE38129 | CDH6 | 1004 | 210601_at | -0.1733 | 0.1199 | |
| GSE45670 | CDH6 | 1004 | 214803_at | -0.6273 | 0.0352 | |
| GSE53622 | CDH6 | 1004 | 14588 | -0.4975 | 0.0001 | |
| GSE53624 | CDH6 | 1004 | 14588 | -0.3238 | 0.0260 | |
| GSE63941 | CDH6 | 1004 | 214803_at | -6.8940 | 0.0000 | |
| GSE77861 | CDH6 | 1004 | 214803_at | 0.1670 | 0.2363 | |
| GSE97050 | CDH6 | 1004 | A_23_P214011 | -0.0359 | 0.9725 | |
| SRP007169 | CDH6 | 1004 | RNAseq | 1.8427 | 0.0076 | |
| SRP008496 | CDH6 | 1004 | RNAseq | 1.8768 | 0.0008 | |
| SRP064894 | CDH6 | 1004 | RNAseq | 0.0140 | 0.9629 | |
| SRP133303 | CDH6 | 1004 | RNAseq | -0.4666 | 0.0036 | |
| SRP159526 | CDH6 | 1004 | RNAseq | -0.2060 | 0.5428 | |
| SRP193095 | CDH6 | 1004 | RNAseq | 0.7804 | 0.0000 | |
| SRP219564 | CDH6 | 1004 | RNAseq | 0.2160 | 0.7143 | |
| TCGA | CDH6 | 1004 | RNAseq | -0.0015 | 0.9937 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CDH6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDH6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDH6 | 1004 | 12 | 0 | 18 | |
| GSE20123 | CDH6 | 1004 | 12 | 0 | 18 | |
| GSE43470 | CDH6 | 1004 | 16 | 3 | 24 | |
| GSE46452 | CDH6 | 1004 | 6 | 21 | 32 | |
| GSE47630 | CDH6 | 1004 | 6 | 12 | 22 | |
| GSE54993 | CDH6 | 1004 | 5 | 4 | 61 | |
| GSE54994 | CDH6 | 1004 | 27 | 2 | 24 | |
| GSE60625 | CDH6 | 1004 | 0 | 0 | 11 | |
| GSE74703 | CDH6 | 1004 | 13 | 2 | 21 | |
| GSE74704 | CDH6 | 1004 | 11 | 0 | 9 | |
| TCGA | CDH6 | 1004 | 50 | 7 | 39 |
Total number of gains: 158; Total number of losses: 51; Total Number of normals: 279.
Somatic mutations of CDH6:
Generating mutation plots.
Highly correlated genes for CDH6:
Showing top 20/558 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDH6 | A1BG | 0.777357 | 3 | 0 | 3 |
| CDH6 | ATF7 | 0.75692 | 3 | 0 | 3 |
| CDH6 | ATL1 | 0.744581 | 3 | 0 | 3 |
| CDH6 | ZNF583 | 0.743084 | 3 | 0 | 3 |
| CDH6 | PKD2 | 0.727621 | 4 | 0 | 4 |
| CDH6 | RBPJ | 0.727334 | 3 | 0 | 3 |
| CDH6 | SEMA6A | 0.713244 | 5 | 0 | 4 |
| CDH6 | NR2F1 | 0.71132 | 3 | 0 | 3 |
| CDH6 | SYNC | 0.706514 | 3 | 0 | 3 |
| CDH6 | DOCK7 | 0.705072 | 3 | 0 | 3 |
| CDH6 | SGTB | 0.703379 | 4 | 0 | 4 |
| CDH6 | PCDH18 | 0.700615 | 8 | 0 | 8 |
| CDH6 | CDIPT | 0.699655 | 3 | 0 | 3 |
| CDH6 | C11orf96 | 0.699213 | 4 | 0 | 4 |
| CDH6 | FBN1 | 0.695815 | 6 | 0 | 5 |
| CDH6 | TCTN3 | 0.695018 | 3 | 0 | 3 |
| CDH6 | WFDC1 | 0.694922 | 9 | 0 | 8 |
| CDH6 | TBX5-AS1 | 0.693249 | 4 | 0 | 4 |
| CDH6 | ANGPTL2 | 0.688125 | 6 | 0 | 6 |
| CDH6 | SGIP1 | 0.68732 | 6 | 0 | 6 |
For details and further investigation, click here
